This pathway is inspired by the LIPID MAPS>Eicosanoids Pathway expended pathway display [https://lipidmaps.org/pathway/pathways_maps] and extended with the bottom left side of Figure 1 from Dennis and Norris (2015 [https://www.ncbi.nlm.nih.gov/pubmed/26139350]).
Eicosanoids are a large group of compounds metabolised from arachidonic acid (AA), either via cyclooxygenases (COX)[https://www.wikipathways.org/index.php/Pathway:WP4347], lipooxygenases(LOX)[https://www.wikipathways.org/index.php/Pathway:WP4348], or cytochrome P450 monooxygenases (CYP)[https://www.wikipathways.org/index.php/Pathway:WP4349].
This pathway visualises the third route, via CYP.

Orange boxes represent peroxisome-proliferator activating receptors (PPARs) potentially activated by the eicosanoids.
This pathway was inferred from Mus musculus pathway [WP4349_106330.gpml] with a 64.0% conversion rate.
New PW, homology converted

[CATALYSIS:idbf713d70]	Invalid interaction type.
[STIMULATION:d5d14]	Invalid interaction type.
[STIMULATION:b6edb]	Invalid interaction type.
[STIMULATION:id807d2b62]	Invalid interaction type.
[STIMULATION:a52d6]	Invalid interaction type.
[PositiveInfluenceReaction:idbf713d70]	Reaction should contain only one reactant and one product.
[Complex:d5816]	Empty element is invalid
[Complex:ce040]	Empty element is invalid