| date |
work |
doi |
| 2022-12-01 |
ABO blood group is involved in the quality of the specific immune response anti-SARS-CoV-2 (edit) |
10.1080/21505594.2021.2019959 |
| 2022-12-01 |
Computational investigation of potent inhibitors against SARS-CoV-2 2′-O-methyltransferase (nsp16): Structure-based pharmacophore modeling, molecular docking, molecular dynamics simulations and binding free energy calculations (edit) |
10.1016/J.JMGM.2022.108306 |
| 2022-09-01 |
Frequent occurrence of mutations in nsp3 and nsp4 of SARS-CoV-2, presumably caused by the inhaled asthma drug ciclesonide (edit) |
10.1093/PNASNEXUS/PGAC197 |
| 2022-08-18 |
In silico identification of novel SARS-CoV-2 main protease and non-structural protein 13 (nsp13) inhibitors through consensus docking and free binding energy calculations. (edit) |
10.2174/1386207325666220818141112 |
| 2022-05-27 |
The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature (edit) |
10.1126/SCIADV.ABO5083 |
| 2022-05-26 |
Parsing the role of NSP1 in SARS-CoV-2 infection (edit) |
|
| 2022-05-20 |
Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity (edit) |
10.1016/J.STR.2022.04.014 |
| 2022-05-12 |
The role of NSP6 in the biogenesis of the SARS-CoV-2 replication organelle (edit) |
10.1038/S41586-022-04835-6 |
| 2022-05-11 |
SARS-CoV-2 Variants of Concern Hijack IFITM2 for Efficient Replication in Human Lung Cells (edit) |
10.1128/JVI.00594-22 |
| 2022-05-09 |
A glucose-like metabolite deficient in diabetes inhibits cellular entry of SARS-CoV-2 (edit) |
10.1038/S42255-022-00567-Z |
| 2022-05-08 |
ADAM10 and ADAM17 promote SARS‐CoV‐2 cell entry and spike protein‐mediated lung cell fusion (edit) |
10.15252/EMBR.202154305 |
| 2022-05-01 |
Recognition and Cleavage of Human tRNA Methyltransferase TRMT1 by the SARS‐CoV‐2 Main Protease (edit) |
10.1096/FASEBJ.2022.36.S1.R4632 |
| 2022-05-01 |
The Effect of Glycosylation Modulators on the Trafficking and Interaction of Spike Protein S1 Subunit and Angiotensin‐Converting Enzyme 2 (edit) |
10.1096/FASEBJ.2022.36.S1.R3340 |
| 2022-05-01 |
Going viral in the islet: mediators of SARS-CoV-2 entry beyond ACE2 (edit) |
10.1530/JME-21-0282 |
| 2022-05-01 |
Variation in ORF3a Protein of SARS‐CoV‐2 Decreases The Severity of Host Cell Damage (edit) |
10.1096/FASEBJ.2022.36.S1.R4149 |
| 2022-05-01 |
Synthesis of the transmembrane domain of the accessory protein ORF7a of SARS‐CoV‐2 using solid phase peptide synthesis and analyzing the oligomerization state (edit) |
10.1096/FASEBJ.2022.36.S1.R3870 |
| 2022-04-25 |
Histamine Potentiates SARS-CoV-2 Spike Protein Entry Into Endothelial Cells (edit) |
10.3389/FPHAR.2022.872736 |
| 2022-04-19 |
Potent Inhibition of SARS-CoV-2 nsp14 N7-Methyltransferase by Sulfonamide-Based Bisubstrate Analogues (edit) |
10.1021/ACS.JMEDCHEM.2C00120 |
| 2022-04-17 |
Clinically observed deletions in SARS-CoV-2 Nsp1 affect its stability and ability to inhibit translation (edit) |
10.1002/1873-3468.14354 |
| 2022-04-12 |
SARS-CoV-2 spike protein–induced cell fusion activates the cGAS-STING pathway and the interferon response (edit) |
10.1126/SCISIGNAL.ABG8744 |
| 2022-04-07 |
SARS-CoV-2 nsp5 Exhibits Stronger Catalytic Activity and Interferon Antagonism than Its SARS-CoV Ortholog (edit) |
10.1128/JVI.00037-22 |
| 2022-04-05 |
Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2 (edit) |
10.1073/PNAS.2117142119 |
| 2022-04-05 |
Online Hydrophilic Interaction Chromatography (HILIC) Enhanced Top-Down Mass Spectrometry Characterization of the SARS-CoV-2 Spike Receptor-Binding Domain (edit) |
10.1021/ACS.ANALCHEM.2C00139 |
| 2022-04-05 |
pH- and Calcium-Dependent Aromatic Network in the SARS-CoV-2 Envelope Protein (edit) |
10.1021/JACS.2C00973 |
| 2022-03-29 |
Intranasal administration of a single dose of a candidate live attenuated vaccine derived from an NSP16-deficient SARS-CoV-2 strain confers sterilizing immunity in animals (edit) |
10.1038/S41423-022-00855-4 |
| 2022-03-28 |
SARS-CoV-2 pseudovirus enters the host cells through spike protein-CD147 in Arf6-dependent manner (edit) |
10.1080/22221751.2022.2059403 |
| 2022-03-28 |
Distinctive Roles of Furin and TMPRSS2 in SARS-CoV-2 Infectivity (edit) |
10.1128/JVI.00128-22 |
| 2022-03-28 |
Viral Mimicry of Interleukin-17A by SARS-CoV-2 ORF8 (edit) |
10.1128/MBIO.00402-22 |
| 2022-03-22 |
SARS-CoV-2 NSP13 helicase suppresses interferon signaling by perturbing JAK1 phosphorylation of STAT1 (edit) |
10.1186/S13578-022-00770-1 |
| 2022-03-22 |
In Silico Insights towards the Identification of SARS-CoV-2 NSP13 Helicase Druggable Pockets (edit) |
10.3390/BIOM12040482 |
| 2022-03-17 |
The SARS-CoV-2 Entry Inhibition Mechanisms of Serine Protease Inhibitors, OM-85, Heparin and Soluble HS Might Be Linked to HS Attachment Sites (edit) |
10.3390/MOLECULES27061947 |
| 2022-03-16 |
Free ISG15 and protein ISGylation emerging in SARS-CoV-2 infection (edit) |
10.2174/1389450123666220316094720 |
| 2022-03-16 |
Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry (edit) |
10.7554/ELIFE.77444 |
| 2022-03-16 |
SARS-CoV-2: Receptor and Co-receptor Tropism Probability (edit) |
10.1007/S00284-022-02807-7 |
| 2022-03-16 |
SARS-CoV-2 Nsp14 mediates the effects of viral infection on the host cell transcriptome (edit) |
10.7554/ELIFE.71945 |
| 2022-03-14 |
When cyclin‐dependent kinases meet viral infections, including SARS‐CoV‐2 (edit) |
10.1002/JMV.27719 |
| 2022-03-08 |
An intra-cytoplasmic route for SARS-CoV-2 transmission unveiled by Helium-ion microscopy (edit) |
10.1038/S41598-022-07867-0 |
| 2022-03-08 |
Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication–transcription complex (edit) |
10.1038/S41594-022-00734-6 |
| 2022-03-07 |
Cytoplasmic domain and enzymatic activity of ACE2 are not required for PI4KB dependent endocytosis entry of SARS-CoV-2 into host cells (edit) |
10.1016/J.VIRS.2022.03.003 |
| 2022-03-03 |
SARS-CoV-2 ORF3a induces RETREG1/FAM134B-dependent reticulophagy and triggers sequential ER stress and inflammatory responses during SARS-CoV-2 infection (edit) |
10.1080/15548627.2022.2039992 |
| 2022-03-01 |
Modulation of the monomer-dimer equilibrium and catalytic activity of SARS-CoV-2 main protease by a transition-state analog inhibitor (edit) |
10.1038/S42003-022-03084-7 |
| 2022-03-01 |
The key features of SARS-CoV-2 leader and NSP1 required for viral escape of NSP1-mediated repression (edit) |
10.1261/RNA.079086.121 |
| 2022-02-28 |
Optimizing peptide inhibitors of SARS-Cov-2 nsp10/nsp16 methyltransferase predicted through molecular simulation and machine learning (edit) |
10.1016/J.IMU.2022.100886 |
| 2022-02-28 |
SARS-CoV-2 nucleocapsid protein targets a conserved surface groove of the NTF2-like domain of G3BP1 (edit) |
10.1016/J.JMB.2022.167516 |
| 2022-02-25 |
A Deadly Embrace: Hemagglutination Mediated by SARS-CoV-2 Spike Protein at Its 22 N-Glycosylation Sites, Red Blood Cell Surface Sialoglycoproteins, and Antibody (edit) |
10.3390/IJMS23052558 |
| 2022-02-24 |
Targeting SARS-CoV-2 Proteases and Polymerase for COVID-19 Treatment: State of the Art and Future Opportunities (edit) |
10.1021/ACS.JMEDCHEM.0C01140 |
| 2022-02-24 |
Viroporins: structure, function, and their role in the life cycle of SARS-CoV-2 (edit) |
10.1016/J.BIOCEL.2022.106185 |
| 2022-02-23 |
Neuropilin‐1‐Mediated SARS‐CoV‐2 Infection in Bone Marrow‐Derived Macrophages Inhibits Osteoclast Differentiation (edit) |
10.1002/ADBI.202200007 |
| 2022-02-23 |
Interactions of Severe Acute Respiratory Syndrome Coronavirus 2 Protein E With Cell Junctions and Polarity PSD-95/Dlg/ZO-1-Containing Proteins (edit) |
10.3389/FMICB.2022.829094 |
| 2022-02-23 |
The stalk domain of SARS-CoV-2 NSP13 is essential for its helicase activity (edit) |
10.1016/J.BBRC.2022.02.068 |
| 2022-02-22 |
The SARS‐CoV‐2 Spike Glycoprotein Directly Binds Exogeneous Sialic Acids: A NMR View (edit) |
10.1002/ANIE.202201432 |
| 2022-02-22 |
Identification of a SARS-CoV-2 host metalloproteinase-dependent entry pathway differentially used by SARS-CoV-2 and variants of concern Alpha, Delta, and Omicron (edit) |
10.1101/2022.02.19.481107 |
| 2022-02-21 |
Decoupling SARS-CoV-2 ORF6 localization and interferon antagonism (edit) |
10.1242/JCS.259666 |
| 2022-02-21 |
SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells (edit) |
10.1016/J.CELREP.2022.110503 |
| 2022-02-18 |
Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity (edit) |
10.1101/2022.02.17.480845 |
| 2022-02-16 |
Lipid and Nucleocapsid N-Protein Accumulation in COVID-19 Patient Lung and Infected Cells (edit) |
10.1128/SPECTRUM.01271-21 |
| 2022-02-15 |
Inhibition of Protein Glycosylation Blocks SARS-CoV-2 Infection (edit) |
10.1128/MBIO.03718-21 |
| 2022-02-14 |
Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN (edit) |
10.1073/PNAS.2106379119 |
| 2022-02-14 |
Strikingly Different Roles of SARS-CoV-2 Fusion Peptides Uncovered by Neutron Scattering (edit) |
10.1021/JACS.1C09856 |
| 2022-02-14 |
Structural polymorphism of coiled‐coils from the stalk domain of SARS‐CoV‐2 spike protein (edit) |
10.1096/FJ.202101670R |
| 2022-02-11 |
SARS-CoV-2 accessory protein ORF8 is secreted extracellularly as a glycoprotein homodimer (edit) |
10.1016/J.JBC.2022.101724 |
| 2022-02-09 |
Integrin mediates cell entry of the SARS-CoV-2 virus independent of cellular receptor ACE2 (edit) |
10.1016/J.JBC.2022.101710 |
| 2022-02-07 |
Cryo-EM structure of the SARS-CoV-2 Omicron spike (edit) |
10.1016/J.CELREP.2022.110428 |
| 2022-02-07 |
The spike protein of SARS-CoV-2 induces endothelial inflammation through integrin α5β1 and NF-κB signaling (edit) |
10.1016/J.JBC.2022.101695 |
| 2022-02-06 |
Identification of potential target endoribonuclease NSP15 inhibitors of SARS-COV-2 from natural products through high-throughput virtual screening and molecular dynamics simulation (edit) |
10.1111/JFBC.14085 |
| 2022-02-01 |
Molecular Docking Studies to Identify Promising Natural Inhibitors Targeting SARS-CoV-2 Nsp10-Nsp16 Protein Complex (edit) |
10.4274/TJPS.GALENOS.2021.56957 |
| 2022-02-01 |
The nsp15 Nuclease as a Good Target to Combat SARS-CoV-2: Mechanism of Action and Its Inactivation with FDA-Approved Drugs (edit) |
10.3390/MICROORGANISMS10020342 |
| 2022-02-01 |
Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant (edit) |
10.1038/S41586-022-04462-1 |
| 2022-02-01 |
Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts tropism and fusogenicity (edit) |
10.1038/S41586-022-04474-X |
| 2022-02-01 |
The E3 Ubiquitin Ligase RNF5 Facilitates SARS-CoV-2 Membrane Protein-Mediated Virion Release (edit) |
10.1128/MBIO.03168-21 |
| 2022-02-01 |
Genome-wide analyses reveal the detrimental impacts of SARS-CoV-2 viral gene Orf9c on human pluripotent stem cell-derived cardiomyocytes (edit) |
10.1016/J.STEMCR.2022.01.014 |
| 2022-01-29 |
The function of SARS-CoV-2 spike protein is impaired by disulfide-bond disruption with mutation at cysteine-488 and by thiol-reactive N-acetyl-cysteine and glutathione (edit) |
10.1016/J.BBRC.2022.01.106 |
| 2022-01-27 |
Effect of SARS-CoV-2 spike mutations on its activation by TMPRSS2 and TMPRSS13 (edit) |
10.1101/2022.01.26.477969 |
| 2022-01-26 |
Trypsin enhances SARS-CoV-2 infection by facilitating viral entry (edit) |
10.1007/S00705-021-05343-0 |
| 2022-01-25 |
Extracellular vimentin is an attachment factor that facilitates SARS-CoV-2 entry into human endothelial cells (edit) |
10.1073/PNAS.2113874119 |
| 2022-01-25 |
N7-Methylation of the Coronavirus RNA Cap Is Required for Maximal Virulence by Preventing Innate Immune Recognition (edit) |
10.1128/MBIO.03662-21 |
| 2022-01-24 |
SARS-CoV-2 NSP5 and N protein counteract the RIG-I signaling pathway by suppressing the formation of stress granules (edit) |
10.1038/S41392-022-00878-3 |
| 2022-01-22 |
Insights into the specificity for the interaction of the promiscuous SARS-CoV-2 nucleocapsid protein N-terminal domain with deoxyribonucleic acids (edit) |
10.1016/J.IJBIOMAC.2022.01.121 |
| 2022-01-21 |
The intrinsically disordered SARS-CoV-2 nucleoprotein in dynamic complex with its viral partner nsp3a (edit) |
10.1126/SCIADV.ABM4034 |
| 2022-01-17 |
Characterization of the SARS-CoV-2 ExoN (nsp14ExoN–nsp10) complex: implications for its role in viral genome stability and inhibitor identification (edit) |
10.1093/NAR/GKAB1303 |
| 2022-01-14 |
Detection and discrimination of SARS-CoV-2 spike protein-derived peptides using THz metamaterials (edit) |
10.1016/J.BIOS.2022.113981 |
| 2022-01-12 |
Syndecan-4 Is a Key Facilitator of the SARS-CoV-2 Delta Variant's Superior Transmission (edit) |
10.3390/IJMS23020796 |
| 2022-01-12 |
SARS-CoV-2 membrane protein causes the mitochondrial apoptosis and pulmonary edema via targeting BOK (edit) |
10.1038/S41418-022-00928-X |
| 2022-01-11 |
Alpha-Soluble NSF Attachment Protein Prevents the Cleavage of the SARS-CoV-2 Spike Protein by Functioning as an Interferon-Upregulated Furin Inhibitor (edit) |
10.1128/MBIO.02443-21 |
| 2022-01-08 |
SARS-CoV-2 non-structural protein 6 triggers NLRP3-dependent pyroptosis by targeting ATP6AP1 (edit) |
10.1038/S41418-021-00916-7 |
| 2022-01-07 |
SARS-CoV-2 NSP13 Inhibits Type I IFN Production by Degradation of TBK1 via p62-Dependent Selective Autophagy (edit) |
10.4049/JIMMUNOL.2100684 |
| 2022-01-07 |
Toward wide-spectrum antivirals against coronaviruses: Molecular characterization of SARS-CoV-2 NSP13 helicase inhibitors (edit) |
10.1126/SCIADV.ABJ4526 |
| 2022-01-05 |
UV-4B potently inhibits replication of multiple SARS-CoV-2 strains in clinically relevant human cell lines (edit) |
10.31083/J.FBL2701003 |
| 2022-01-04 |
SARS-CoV-2 spike engagement of ACE2 primes S2' site cleavage and fusion initiation (edit) |
10.1073/PNAS.2111199119 |
| 2022-01-03 |
The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanism (edit) |
10.1101/2022.01.03.21268111 |
| 2022-01-01 |
Identification of fragments binding to SARS-CoV-2 nsp10 reveals ligand-binding sites in conserved interfaces between nsp10 and nsp14/nsp16 (edit) |
10.1039/D1CB00135C |
| 2022-01-01 |
Proteolytic activation of SARS-CoV-2 spike protein (edit) |
10.1111/1348-0421.12945 |
| 2022-01-01 |
Glycomimetic ligands block the interaction of SARS-CoV-2 spike protein with C-type lectin co-receptors (edit) |
10.1039/D2CC00121G |
| 2022-01-01 |
D155Y substitution of SARS-CoV-2 ORF3a weakens binding with Caveolin-1 (edit) |
10.1016/J.CSBJ.2022.01.017 |
| 2022-01-01 |
Understanding the Role of SARS-CoV-2 ORF3a in Viral Pathogenesis and COVID-19 (edit) |
10.3389/FMICB.2022.854567 |
| 2021-12-31 |
Cellular miR-150-5p may have a crucial role to play in the biology of SARS-CoV-2 infection by regulating nsp10 gene (edit) |
10.1080/15476286.2021.2010959 |
| 2021-12-30 |
Interactome profiling reveals interaction of SARS-CoV-2 NSP13 with host factor STAT1 to suppress interferon signaling (edit) |
10.1093/JMCB/MJAB068 |
| 2021-12-27 |
The interactions of ZDHHC5/GOLGA7 with SARS-CoV-2 spike (S) protein and their effects on S protein's subcellular localization, palmitoylation and pseudovirus entry (edit) |
10.1186/S12985-021-01722-W |
| 2021-12-24 |
SARS-CoV-2 Omicron variant shows less efficient replication and fusion activity when compared with delta variant in TMPRSS2-expressed cells (edit) |
10.1080/22221751.2021.2023329 |
| 2021-12-24 |
Modulation of the NLRP3 inflammasome by Sars-CoV-2 Envelope protein (edit) |
10.1038/S41598-021-04133-7 |
| 2021-12-22 |
The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147 receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease (edit) |
10.1042/CS20210735 |
| 2021-12-20 |
Activation of the SARS-CoV-2 NSP14 3'-5' exoribonuclease by NSP10 and response to antiviral inhibitors (edit) |
10.1016/J.JBC.2021.101518 |
| 2021-12-17 |
The binding of heparin to spike glycoprotein inhibits SARS-CoV-2 infection by three mechanisms (edit) |
10.1016/J.JBC.2021.101507 |
| 2021-12-17 |
SARS-CoV-2-triggered mast cell rapid degranulation induces alveolar epithelial inflammation and lung injury (edit) |
10.1038/S41392-021-00849-0 |
| 2021-12-15 |
Highly conserved s2m element of SARS-CoV-2 dimerizes via a kissing complex and interacts with host miRNA-1307-3p (edit) |
10.1093/NAR/GKAB1226 |
| 2021-12-15 |
Metalloproteinase-dependent and TMPRSS2-independnt cell surface entry pathway of SARS-CoV-2 requires the furin-cleavage site and the S2 domain of spike protein (edit) |
10.1101/2021.12.14.472513 |
| 2021-12-13 |
Exploring the therapeutic nature of limonoids and triterpenoids against SARS-CoV-2 by targeting nsp13, nsp14, and nsp15 through molecular docking and dynamics simulations (edit) |
10.1016/J.JTCME.2021.12.002 |
| 2021-12-10 |
Membrane fusion and immune evasion by the spike protein of SARS-CoV-2 Delta variant (edit) |
10.1126/SCIENCE.ABL9463 |
| 2021-12-09 |
SARS-CoV-2 ORF3a Induces Incomplete Autophagy via the Unfolded Protein Response (edit) |
10.3390/V13122467 |
| 2021-12-07 |
N-glycosylation profiles of the SARS-CoV-2 spike D614G mutant and its ancestral protein characterized by advanced mass spectrometry (edit) |
10.1038/S41598-021-02904-W |
| 2021-12-07 |
Cell fusion as a link between the SARS-CoV-2 spike protein, COVID-19 complications, and vaccine side effects (edit) |
10.18632/ONCOTARGET.28088 |
| 2021-12-06 |
SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-kB pathway (edit) |
10.7554/ELIFE.68563 |
| 2021-12-06 |
Forced association of SARS-CoV-2 proteins with the yeast proteome perturb vesicle trafficking (edit) |
10.15698/MIC2021.12.766 |
| 2021-12-05 |
Extracellular Vimentin as a Target Against SARS‐CoV‐2 Host Cell Invasion (edit) |
10.1002/SMLL.202105640 |
| 2021-12-04 |
SARS-CoV-2 Nucleocapsid protein attenuates stress granules and interacts with mRNAs to impair host stress response (edit) |
10.1016/J.ISCI.2021.103562 |
| 2021-12-04 |
A structural view of the SARS-CoV-2 virus and its assembly (edit) |
10.1016/J.COVIRO.2021.11.011 |
| 2021-12-03 |
SARS-CoV-2 Nsp5 Protein Causes Acute Lung Inflammation, A Dynamical Mathematical Model (edit) |
10.3389/FSYSB.2021.764155 |
| 2021-12-01 |
Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formation (edit) |
10.1038/S41467-021-27511-1 |
| 2021-12-01 |
Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate (edit) |
10.1080/22221751.2021.1932607 |
| 2021-12-01 |
Pannexin-1 channel opening is critical for COVID-19 pathogenesis (edit) |
10.1016/J.ISCI.2021.103478 |
| 2021-12-01 |
SARS-CoV-2 uses metabotropic glutamate receptor subtype 2 as an internalization factor to infect cells (edit) |
10.1038/S41421-021-00357-Z |
| 2021-12-01 |
The spike protein of SARS-CoV-2 virus induces heme oxygenase-1: Pathophysiologic implications (edit) |
10.1016/J.BBADIS.2021.166322 |
| 2021-12-01 |
SARS-CoV-2 pseudovirus infectivity and expression of viral entry-related factors ACE2, TMPRSS2, Kim-1, and NRP-1 in human cells from the respiratory, urinary, digestive, reproductive, and immune systems (edit) |
10.1002/JMV.27244 |
| 2021-12-01 |
SARS-CoV-2 interaction with Siglec-1 mediates trans-infection by dendritic cells (edit) |
10.1038/S41423-021-00794-6 |
| 2021-12-01 |
The short isoform of the host antiviral protein ZAP acts as an inhibitor of SARS-CoV-2 programmed ribosomal frameshifting (edit) |
10.1038/S41467-021-27431-0 |
| 2021-11-30 |
Multiplex Gene Tagging with CRISPR-Cas9 for Live-Cell Microscopy and Application to Study the Role of SARS-CoV-2 Proteins in Autophagy, Mitochondrial Dynamics, and Cell Growth (edit) |
10.1089/CRISPR.2021.0041 |
| 2021-11-29 |
SARS-CoV-2 ORF10 suppresses the antiviral innate immune response by degrading MAVS through mitophagy (edit) |
10.1038/S41423-021-00807-4 |
| 2021-11-29 |
The SARS-CoV-2 RNA polymerase is a viral RNA capping enzyme (edit) |
10.1093/NAR/GKAB1160 |
| 2021-11-26 |
Oxidative stress transforms 3CLpro into an insoluble and more active form to promote SARS-CoV-2 replication (edit) |
10.1016/J.REDOX.2021.102199 |
| 2021-11-26 |
Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2 (edit) |
10.1038/S41422-021-00595-6 |
| 2021-11-25 |
Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation (edit) |
10.1038/S41586-021-04266-9 |
| 2021-11-24 |
Glycosylation and disulfide bonding of wild-type SARS-CoV-2 spike glycoprotein (edit) |
10.1128/JVI.01626-21 |
| 2021-11-23 |
SARS‐CoV‐2 N Protein Induces Acute Kidney Injury via Smad3‐Dependent G1 Cell Cycle Arrest Mechanism (edit) |
10.1002/ADVS.202103248 |
| 2021-11-22 |
TMPRSS2 promotes SARS-CoV-2 evasion from NCOA7-mediated restriction (edit) |
10.1371/JOURNAL.PPAT.1009820 |
| 2021-11-18 |
Backbone and Ile, Leu, Val methyl group resonance assignment of CoV-Y domain of SARS-CoV-2 non-structural protein 3 (edit) |
10.1007/S12104-021-10059-Y |
| 2021-11-18 |
Clinical Antiviral Drug Arbidol Inhibits Infection by SARS-CoV-2 and Variants through Direct Binding to the Spike Protein (edit) |
10.1021/ACSCHEMBIO.1C00756 |
| 2021-11-18 |
The role of cell surface sialic acids for SARS-CoV-2 infection (edit) |
10.1093/GLYCOB/CWAB032 |
| 2021-11-15 |
The glycosylation in SARS-CoV-2 and its receptor ACE2 (edit) |
10.1038/S41392-021-00809-8 |
| 2021-11-15 |
Nanometer-resolution in situ structure of the SARS-CoV-2 postfusion spike protein (edit) |
10.1073/PNAS.2112703118 |
| 2021-11-15 |
SARS-CoV-2 spike protein removes lipids from model membranes and interferes with the capacity of high density lipoprotein to exchange lipids (edit) |
10.1016/J.JCIS.2021.06.056 |
| 2021-11-15 |
SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis (edit) |
10.1038/S41467-021-26910-8 |
| 2021-11-13 |
SARS-CoV-2 deregulates the vascular and immune functions of brain pericytes via Spike protein (edit) |
10.1016/J.NBD.2021.105561 |
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Disulfide bonds play a critical role in the structure and function of the receptor-binding domain of the SARS-CoV-2 Spike antigen (edit) |
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| 2021-11-11 |
Epigenetic glycosylation of SARS-CoV-2 impact viral infection through DC&L-SIGN receptors (edit) |
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Molecular docking and pharmacokinetic studies of phytocompounds from Nigerian Medicinal Plants as promising inhibitory agents against SARS-CoV-2 methyltransferase (nsp16) (edit) |
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Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2 (edit) |
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In-solution buffer-free digestion allows full-sequence coverage and complete characterization of post-translational modifications of the receptor-binding domain of SARS-CoV-2 in a single ESI–MS spectrum (edit) |
10.1007/S00216-021-03721-W |
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CTD of SARS‐CoV‐2 N protein is a cryptic domain for binding ATP and nucleic acid that interplay in modulating phase separation (edit) |
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Furin cleavage of the SARS-CoV-2 spike is modulated by O-glycosylation (edit) |
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SARS-CoV-2 Spike Protein S1-Mediated Endothelial Injury and Pro-Inflammatory State Is Amplified by Dihydrotestosterone and Prevented by Mineralocorticoid Antagonism (edit) |
10.3390/V13112209 |
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Membranotropic and biological activities of the membrane fusion peptides from SARS-CoV spike glycoprotein: The importance of the complete internal fusion peptide domain (edit) |
10.1016/J.BBAMEM.2021.183697 |
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Zn‐Induced Interactions Between SARS‐CoV‐2 orf7a and BST2/Tetherin (edit) |
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Structural basis for the interaction of SARS‐CoV‐2 virulence factor nsp1 with DNA Polymerase a ‐ Primase (edit) |
10.1002/PRO.4220 |
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SARS-CoV-2 spike protein causes blood coagulation and thrombosis by competitive binding to heparan sulfate (edit) |
10.1016/J.IJBIOMAC.2021.10.112 |
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A natural product compound inhibits coronaviral replication in vitro by binding to the conserved Nsp9 SARS-CoV-2 protein (edit) |
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Structural, Electronic, and Electrostatic Determinants for Inhibitor Binding to Subsites S1 and S2 in SARS-CoV-2 Main Protease (edit) |
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SARS-CoV-2 exploits host DGAT and ADRP for efficient replication (edit) |
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Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CL substrate degradome (edit) |
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Betacoronavirus Assembly: Clues and Perspectives for Elucidating SARS-CoV-2 Particle Formation and Egress (edit) |
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SARS-CoV-2 Spike Protein Disrupts Blood-Brain Barrier Integrity via RhoA Activation (edit) |
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The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells (edit) |
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Micronucleus production, activation of DNA damage response and cGAS-STING signaling in syncytia induced by SARS-CoV-2 infection (edit) |
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Altered ISGylation drives aberrant macrophage-dependent immune responses during SARS-CoV-2 infection (edit) |
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SARS-CoV-2 promotes RIPK1 activation to facilitate viral propagation (edit) |
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Integrin activation is an essential component of SARS-CoV-2 infection (edit) |
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The effect of glycosylation of SARS-CoV-2 spike protein on the virus interaction with the host cell ACE2 receptor (edit) |
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SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro (edit) |
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B.1.617.2 enters and fuses lung cells with increased efficiency and evades antibodies induced by infection and vaccination (edit) |
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SARS-CoV-2 nucleocapsid protein forms condensates with viral genomic RNA (edit) |
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ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress (edit) |
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SARS-CoV-2 spike protein harnesses SNX27-mediated endocytic recycling pathway (edit) |
10.1002/MCO2.92 |
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Highly efficient SARS-CoV-2 infection of human cardiomyocytes: spike protein-mediated cell fusion and its inhibition (edit) |
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Mechanisms of SARS-CoV-2 entry into cells (edit) |
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SARS‐CoV‐2 Alpha, Beta and Delta variants display enhanced Spike‐mediated Syncytia Formation (edit) |
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6-Thioguanine blocks SARS-CoV-2 replication by inhibition of PLpro (edit) |
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The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation (edit) |
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The mechanism and consequences of SARS-CoV-2 spike-mediated fusion and syncytia formation (edit) |
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S-acylation controls SARS-CoV-2 membrane lipid organization and enhances infectivity (edit) |
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O-glycosylation pattern of the SARS-CoV-2 spike protein reveals an "O-Follow-N" rule (edit) |
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An evidence that SARS-Cov-2/COVID-19 spike protein (SP) damages hematopoietic stem/progenitor cells in the mechanism of pyroptosis in Nlrp3 inflammasome-dependent manner (edit) |
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Proteases and variants: context matters for SARS-CoV-2 entry assays (edit) |
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Targeting the coronavirus nucleocapsid protein through GSK-3 inhibition (edit) |
10.1073/PNAS.2113401118 |
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The N-terminal domain of SARS-CoV-2 nsp1 plays key roles in suppression of cellular gene expression and preservation of viral gene expression (edit) |
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ORF3a Protein of Severe Acute Respiratory Syndrome Coronavirus 2 Inhibits Interferon-Activated Janus Kinase/Signal Transducer and Activator of Transcription Signaling via Elevating Suppressor of Cytokine Signaling 1 (edit) |
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Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U (edit) |
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Identifying Distinct Structural Features of the SARS-CoV-2 Spike Protein Fusion Domain Essential for Membrane Interaction (edit) |
10.1021/ACS.BIOCHEM.1C00543 |
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Palmitoylation of SARS‐CoV‐2 S protein is critical for S‐mediated syncytia formation and virus entry (edit) |
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SARS-CoV-2 spike protein receptor-binding domain N-glycans facilitate viral internalization in respiratory epithelial cells (edit) |
10.1016/J.BBRC.2021.09.053 |
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Direct activation of endothelial cells by SARS-CoV-2 nucleocapsid protein is blocked by Simvastatin (edit) |
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Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential (edit) |
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SARS-CoV-2 Nsp5 Demonstrates Two Distinct Mechanisms Targeting RIG-I and MAVS To Evade the Innate Immune Response (edit) |
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SARS-CoV-2 S glycoprotein binding to multiple host receptors enables cell entry and infection (edit) |
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On the weak binding and spectroscopic signature of SARS‐CoV‐2 nsp14 interaction with RNA (edit) |
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A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses (edit) |
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Assessment of the binding interactions of SARS-CoV-2 spike glycoprotein variants (edit) |
10.1016/J.JPHA.2021.09.006 |
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SARS-CoV-2 nucleocapsid suppresses host pyroptosis by blocking Gasdermin D cleavage (edit) |
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MOV10 Helicase Interacts with Coronavirus Nucleocapsid Protein and Has Antiviral Activity (edit) |
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Infection and transmission of SARS‐CoV‐2 depends on heparan sulfate proteoglycans (edit) |
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Sequences in the cytoplasmic tail of SARS-CoV-2 Spike facilitate expression at the cell surface and syncytia formation (edit) |
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A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease (edit) |
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Interactome Analysis of the Nucleocapsid Protein of SARS-CoV-2 Virus (edit) |
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Structure of SARS-CoV-2 spike protein (edit) |
10.1016/J.COVIRO.2021.08.010 |
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Deamidation drives molecular aging of the SARS-CoV-2 spike protein receptor-binding motif (edit) |
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SARS-CoV-2 3C-like protease antagonizes interferon-beta production by facilitating the degradation of IRF3 (edit) |
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Manipulation of autophagy by SARS-CoV-2 proteins (edit) |
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The SARS-CoV-2 Nsp3 macrodomain reverses PARP9/DTX3L-dependent ADP-ribosylation induced by interferon signaling (edit) |
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A dual-role of SARS-CoV-2 nucleocapsid protein in regulating innate immune response (edit) |
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Cellular host factors for SARS-CoV-2 infection (edit) |
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Mechanical activation of spike fosters SARS-CoV-2 viral infection (edit) |
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Impact of temperature on the affinity of SARS-CoV-2 Spike glycoprotein for host ACE2 (edit) |
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D614G Substitution of SARS-CoV-2 Spike Protein Increases Syncytium Formation and Virus Titer via Enhanced Furin-Mediated Spike Cleavage (edit) |
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The nucleotide addition cycle of the SARS-CoV-2 polymerase (edit) |
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Substrate Specificity of SARS-CoV-2 Nsp10-Nsp16 Methyltransferase (edit) |
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Discovering potential inhibitors against SARS-CoV-2 by targeting Nsp13 Helicase (edit) |
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Host ADP-ribosylation and the SARS-CoV-2 macrodomain (edit) |
10.1042/BST20201212 |
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SARS-CoV-2 spike promotes inflammation and apoptosis through autophagy by ROS-suppressed PI3K/AKT/mTOR signaling (edit) |
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Recognition of Divergent Viral Substrates by the SARS-CoV-2 Main Protease (edit) |
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Phosphorylation of SARS-CoV-2 Orf9b Regulates Its Targeting to Two Binding Sites in TOM70 and Recruitment of Hsp90 (edit) |
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SARS-CoV-2 Membrane Glycoprotein M Triggers Apoptosis With the Assistance of Nucleocapsid Protein N in Cells (edit) |
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Targeted in situ cross-linking mass spectrometry and integrative modeling reveal the architectures of three proteins from SARS-CoV-2 (edit) |
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Pyroptosis of syncytia formed by fusion of SARS-CoV-2 spike and ACE2-expressing cells (edit) |
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Multiple Roles of SARS-CoV-2 N Protein Facilitated by Proteoform-Specific Interactions with RNA, Host Proteins, and Convalescent Antibodies (edit) |
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Cell-Free Hemoglobin Does Not Attenuate the Effects of SARS-CoV-2 Spike Protein S1 Subunit in Pulmonary Endothelial Cells (edit) |
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SARS-CoV-2 Proteins Bind to Hemoglobin and Its Metabolites (edit) |
10.3390/IJMS22169035 |
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Genome-wide CRISPR activation screen identifies candidate receptors for SARS-CoV-2 entry (edit) |
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A glycan gate controls opening of the SARS-CoV-2 spike protein (edit) |
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Molecular determinants for regulation of G3BP1/2 phase separation by the SARS-CoV-2 nucleocapsid protein (edit) |
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Regulation of the Dimerization and Activity of SARS-CoV-2 Main Protease through Reversible Glutathionylation of Cysteine 300 (edit) |
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Structure and Function of N-Terminal Zinc Finger Domain of SARS-CoV-2 NSP2 (edit) |
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The challenge of structural heterogeneity in the native mass spectrometry studies of the SARS-CoV-2 spike protein interactions with its host cell-surface receptor (edit) |
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The Structure-Based Design of SARS-CoV-2 nsp14 Methyltransferase Ligands Yields Nanomolar Inhibitors (edit) |
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A distinct ssDNA/RNA binding interface in the Nsp9 protein from SARS-CoV-2 (edit) |
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Role of ATP in the RNA Translocation Mechanism of SARS-CoV-2 NSP13 Helicase (edit) |
10.1021/ACS.JPCB.1C04528 |
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Structural O-Glycoform Heterogeneity of the SARS-CoV-2 Spike Protein Receptor-Binding Domain Revealed by Top-Down Mass Spectrometry (edit) |
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Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase (edit) |
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Contribution of SARS-CoV-2 Accessory Proteins to Viral Pathogenicity in K18 Human ACE2 Transgenic Mice (edit) |
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NMPylation and de-NMPylation of SARS-CoV-2 nsp9 by the NiRAN domain (edit) |
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Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication (edit) |
10.1016/J.BPJ.2021.06.006 |
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SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation (edit) |
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Why All the Fury over Furin? (edit) |
10.1021/ACS.JMEDCHEM.1C00518 |
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Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors (edit) |
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S-acylation of SARS-CoV-2 Spike Protein: Mechanistic Dissection, In Vitro Reconstitution and Role in Viral Infectivity (edit) |
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Predictable fold switching by the SARS-CoV-2 protein ORF9b (edit) |
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Heparin: A simplistic repurposing to prevent SARS-CoV-2 transmission in light of its in-vitro nanomolar efficacy (edit) |
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Quantum simulations of SARS-CoV-2 main protease M enable high-quality scoring of diverse ligands (edit) |
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SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: Implications for microclot formation in COVID-19 (edit) |
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Correlative multi-scale cryo-imaging unveils SARS-CoV-2 assembly and egress (edit) |
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Localization of SARS-CoV-2 Capping Enzymes Revealed by an Antibody against the nsp10 Subunit (edit) |
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SARS-CoV-2 infection induces the activation of tissue factor-mediated coagulation via activation of acid sphingomyelinase (edit) |
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CD209L/L-SIGN and CD209/DC-SIGN Act as Receptors for SARS-CoV-2 (edit) |
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IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro (edit) |
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Structural basis of mismatch recognition by a SARS-CoV-2 proofreading enzyme (edit) |
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SARS-CoV-2 infection triggers widespread host mRNA decay leading to an mRNA export block (edit) |
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SARS-CoV-2 N Protein Targets TRIM25-Mediated RIG-I Activation to Suppress Innate Immunity (edit) |
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The Inherent Dynamics and Interaction Sites of the SARS-CoV-2 Nucleocapsid N-Terminal Region (edit) |
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Experimental Evidence for Enhanced Receptor Binding by Rapidly Spreading SARS-CoV-2 Variants (edit) |
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L-SIGN is a receptor on liver sinusoidal endothelial cells for SARS-CoV-2 virus (edit) |
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Genome-wide analysis of protein-protein interactions and involvement of viral proteins in SARS-CoV-2 replication (edit) |
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The virological impacts of SARS-CoV-2 D614G mutation (edit) |
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Lipid bilayer degradation induced by SARS-CoV-2 spike protein as revealed by neutron reflectometry (edit) |
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Comprehensive O-Glycosylation Analysis of the SARS-CoV-2 Spike Protein with Biomimetic Trp-Arg Materials (edit) |
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp15 endoribonuclease (edit) |
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Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies (edit) |
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp13 helicase (edit) |
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Genomic characterization of SARS-CoV-2 isolates from patients in Turkey reveals the presence of novel mutations in spike and nsp12 proteins (edit) |
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A head-to-head comparison of the inhibitory activities of 15 peptidomimetic SARS-CoV-2 3CLpro inhibitors (edit) |
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Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell (edit) |
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Viral MicroRNAs Encoded by Nucleocapsid Gene of SARS-CoV-2 Are Detected during Infection, and Targeting Metabolic Pathways in Host Cells (edit) |
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Targeting liquid–liquid phase separation of SARS-CoV-2 nucleocapsid protein promotes innate antiviral immunity by elevating MAVS activity (edit) |
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SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction (edit) |
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Determination of intermediate state structures in the opening pathway of SARS-CoV-2 spike using cryo-electron microscopy (edit) |
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Kidney injury molecule-1 is a potential receptor for SARS-CoV-2 (edit) |
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Recombinant SARS-CoV-2 envelope protein traffics to the trans-Golgi network following amphipol-mediated delivery into human cells (edit) |
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease (edit) |
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Implications of Spike-glycoprotein processing at S1/S2 by Furin, at S2’ by Furin and/or TMPRSS2 and shedding of ACE2: cell-to-cell fusion, cell entry and infectivity of SARS-CoV-2 (edit) |
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Site-Specific Steric Control of SARS-CoV-2 Spike Glycosylation (edit) |
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase (edit) |
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Coronavirus genomic nsp14-ExoN, structure, role, mechanism, and potential application as a drug target (edit) |
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SARS-Cov-2 spike protein fragment 674–685 protects mitochondria from releasing cytochrome c in response to apoptogenic influence (edit) |
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A weak COPI binding motif in the cytoplasmic tail of SARS-CoV-2 spike glycoprotein is necessary for its cleavage, glycosylation, and localization (edit) |
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Variations in Orf3a protein of SARS-CoV-2 alter its structure and function (edit) |
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Mutations in SARS-CoV-2 nsp7 and nsp8 proteins and their predicted impact on replication/transcription complex structure (edit) |
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Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors (edit) |
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Binding of the SARS-CoV-2 spike protein to glycans (edit) |
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Exploitation of the Secretory Pathway by SARS-CoV-2 Envelope (edit) |
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Identification of a High-Frequency Intrahost SARS-CoV-2 Spike Variant with Enhanced Cytopathic and Fusogenic Effects (edit) |
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Activation of NF-κB and induction of proinflammatory cytokine expressions mediated by ORF7a protein of SARS-CoV-2 (edit) |
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Allosteric Activation of SARS-CoV-2 RNA-Dependent RNA Polymerase by Remdesivir Triphosphate and Other Phosphorylated Nucleotides (edit) |
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The endogenous cellular protease inhibitor SPINT2 controls SARS-CoV-2 viral infection and is associated to disease severity (edit) |
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Energetic and structural features of SARS-CoV-2 N-protein co-assemblies with nucleic acids (edit) |
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TMPRSS2 expression dictates the entry route used by SARS‐CoV‐2 to infect host cells (edit) |
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SARS-CoV-2 spike protein induces paracrine senescence and leukocyte adhesion in endothelial cells (edit) |
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Deletion of ER-retention motif on SARS-CoV-2 spike protein reduces cell hybrid during cell–cell fusion (edit) |
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Heparan Sulfate Proteoglycans as Attachment Factor for SARS-CoV-2 (edit) |
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Nsp2 has the potential to be a drug target revealed by global identification of SARS-CoV-2 Nsp2-interacting proteins (edit) |
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Impact of Expressing Cells on Glycosylation and Glycan of the SARS-CoV-2 Spike Glycoprotein (edit) |
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Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs (edit) |
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Structure-function relations of the SARS-CoV-2 spike protein and impact of mutations in the variants of concern (edit) |
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Heparan Sulfate Proteoglycans in Viral Infection and Treatment: A Special Focus on SARS-CoV-2 (edit) |
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SARS-CoV-2 NSP12 protein is not an IFN-β antagonist (edit) |
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Mn2+ coordinates Cap-0-RNA to align substrates for efficient 2'--methyl transfer by SARS-CoV-2 nsp16 (edit) |
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Revealing the Structural Plasticity of SARS-CoV-2 nsp7 and nsp8 Using Structural Proteomics (edit) |
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Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain (edit) |
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Endothelial glycocalyx shields the interaction of SARS-CoV-2 spike protein with ACE2 receptors (edit) |
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SARS-CoV-2 Envelope (E) protein interacts with PDZ-domain-2 of host tight junction protein ZO1 (edit) |
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Structural basis for SARS-CoV-2 envelope protein recognition of human cell junction protein PALS1 (edit) |
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10.1016/J.TIBS.2021.06.001 |
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10.1101/2021.06.06.446826 |
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Fe-S cofactors in the SARS-CoV-2 RNA-dependent RNA polymerase are potential antiviral targets (edit) |
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A metal ion orients SARS-CoV-2 mRNA to ensure accurate 2′-O methylation of its first nucleotide (edit) |
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Epigallocatechin Gallate Inhibits the Uridylate-Specific Endoribonuclease Nsp15 and Efficiently Neutralizes the SARS-CoV-2 Strain (edit) |
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Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry (edit) |
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Surface Proteins of SARS-CoV-2 Drive Airway Epithelial Cells to Induce IFN-Dependent Inflammation (edit) |
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Neuropilin-1 Assists SARS-CoV-2 Infection by Stimulating the Separation of Spike Protein Domains S1 and S2 (edit) |
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SARS-CoV-2 mutation 614G creates an elastase cleavage site enhancing its spread in high AAT-deficient regions (edit) |
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Multiple sites on SARS-CoV-2 spike protein are susceptible to proteolysis by cathepsins B, K, L, S, and V (edit) |
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The envelope protein of SARS-CoV-2 increases intra-Golgi pH and forms a cation channel that is regulated by pH (edit) |
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SARS-CoV-2 genomic surveillance identifies naturally occurring truncation of ORF7a that limits immune suppression (edit) |
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ALG-097111, a potent and selective SARS-CoV-2 3-chymotrypsin-like cysteine protease inhibitor exhibits in vivo efficacy in a Syrian Hamster model (edit) |
10.1016/J.BBRC.2021.03.096 |
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Probing effects of the SARS-CoV-2 E protein on membrane curvature and intracellular calcium (edit) |
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Translational shutdown and evasion of the innate immune response by SARS-CoV-2 NSP14 protein (edit) |
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NPC1-regulated dynamic of clathrin-coated pits is essential for viral entry (edit) |
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Similarities and differences in the conformational stability and reversibility of ORF8, an accessory protein of SARS-CoV-2, and its L84S variant (edit) |
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2'-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography (edit) |
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SARS-CoV-2 nucleocapsid protein impairs stress granule formation to promote viral replication (edit) |
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Azelastine inhibits viropexis of SARS-CoV-2 spike pseudovirus by binding to SARS-CoV-2 entry receptor ACE2 (edit) |
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SARS-CoV-2 simulations go exascale to predict dramatic spike opening and cryptic pockets across the proteome (edit) |
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Viewing SARS-CoV-2 Nucleocapsid Protein in Terms of Molecular Flexibility (edit) |
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The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι (edit) |
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Hepatitis C virus drugs that inhibit SARS-CoV-2 papain-like protease synergize with remdesivir to suppress viral replication in cell culture (edit) |
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Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity (edit) |
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Two conserved oligomer interfaces of NSP7 and NSP8 underpin the dynamic assembly of SARS-CoV-2 RdRP (edit) |
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The human pandemic coronaviruses on the show: The spike glycoprotein as the main actor in the coronaviruses play (edit) |
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Heparan sulfates from bat and human lung and their binding to the spike protein of SARS-CoV-2 virus (edit) |
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SARS-CoV-2 Fusion Peptide has a Greater Membrane Perturbating Effect than SARS-CoV with Highly Specific Dependence on Ca (edit) |
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Glucosidase inhibitors suppress SARS-CoV-2 in tissue culture and may potentiate (edit) |
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Crystal structure of SARS-CoV-2 Orf9b in complex with human TOM70 suggests unusual virus-host interactions (edit) |
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Variable post-translational modifications of SARS-CoV-2 nucleocapsid protein (edit) |
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A SARS-CoV-2 antibody curbs viral nucleocapsid protein-induced complement hyperactivation (edit) |
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Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex (edit) |
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A comprehensive library of fluorescent constructs of SARS‐CoV‐2 proteins and their initial characterisation in different cell types (edit) |
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X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease (edit) |
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TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines (edit) |
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The SARS-CoV-2 protein ORF3a inhibits fusion of autophagosomes with lysosomes (edit) |
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Arginine Methylation of SARS-Cov-2 Nucleocapsid Protein Regulates RNA Binding, its Ability to Suppress Stress Granule Formation and Viral Replication (edit) |
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DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist (edit) |
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SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity (edit) |
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Interferon antagonism by SARS-CoV-2: a functional study using reverse genetics (edit) |
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SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2 (edit) |
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Reconstitution and functional characterization of SARS-CoV-2 proofreading complex (edit) |
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SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies (edit) |
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Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity (edit) |
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SARS-CoV-2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING signaling pathways (edit) |
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Coiled-coil heterodimers with increased stability for cellular regulation and sensing SARS-CoV-2 spike protein-mediated cell fusion (edit) |
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The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets (edit) |
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ORF10-Cullin-2-ZYG11B complex is not required for SARS-CoV-2 infection (edit) |
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RNA-induced liquid phase separation of SARS-CoV-2 nucleocapsid protein facilitates NF-κB hyper-activation and inflammation (edit) |
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SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation (edit) |
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ORF8 contributes to cytokine storm during SARS-CoV-2 infection by activating IL-17 pathway (edit) |
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High-throughput screening of the ReFRAME, Pandemic Box, and COVID Box drug repurposing libraries against SARS-CoV-2 nsp15 endoribonuclease to identify small-molecule inhibitors of viral activity (edit) |
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The SARS‐unique domain (SUD) of SARS‐CoV and SARS‐CoV‐2 interacts with human Paip1 to enhance viral RNA translation (edit) |
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SARS-CoV-2 spike protein dictates syncytium-mediated lymphocyte elimination (edit) |
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The Mechanism of SARS-CoV-2 Nucleocapsid Protein Recognition by the Human 14-3-3 Proteins (edit) |
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Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system (edit) |
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A unique view of SARS-COV-2 through the lens of ORF8 protein (edit) |
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SARS-CoV-2 ORF6 Disrupts Bidirectional Nucleocytoplasmic Transport through Interactions with Rae1 and Nup98 (edit) |
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SARS-CoV-2 and SARS-CoV Spike-Mediated Cell-Cell Fusion Differ in Their Requirements for Receptor Expression and Proteolytic Activation (edit) |
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The Polybasic Cleavage Site in SARS-CoV-2 Spike Modulates Viral Sensitivity to Type I Interferon and IFITM2 (edit) |
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Human airway cells prevent SARS-CoV-2 multibasic cleavage site cell culture adaptation (edit) |
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The Spike Glycoprotein of SARS-CoV-2 Binds to β1 Integrins Expressed on the Surface of Lung Epithelial Cells (edit) |
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Structural Insights into Plasticity and Discovery of Remdesivir Metabolite GS-441524 Binding in SARS-CoV-2 Macrodomain (edit) |
10.1021/ACSMEDCHEMLETT.0C00684 |
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The SARS-CoV-2 Nsp3 macrodomain reverses PARP9/DTX3L-dependent ADP-ribosylation induced by interferon signalling (edit) |
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Repositioning of histamine H receptor antagonist: Doxepin inhibits viropexis of SARS-CoV-2 Spike pseudovirus by blocking ACE2 (edit) |
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Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN (edit) |
10.1101/2021.04.02.438274 |
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ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity (edit) |
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Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking (edit) |
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H, C and N backbone chemical shift assignments of SARS-CoV-2 nsp3a (edit) |
10.1007/S12104-020-10001-8 |
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Nucleocapsid and Spike Proteins of SARS-CoV-2 Drive Neutrophil Extracellular Trap Formation (edit) |
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The highly flexible disordered regions of the SARS-CoV-2 nucleocapsid N protein within the 1-248 residue construct: sequence-specific resonance assignments through NMR (edit) |
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Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia (edit) |
10.1016/J.CELL.2021.04.033 |
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Testing of the inhibitory effects of loratadine and desloratadine on SARS-CoV-2 spike pseudotyped virus viropexis (edit) |
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The Role of the SARS-CoV-2 S-Protein Glycosylation in the Interaction of SARS-CoV-2/ACE2 and Immunological Responses (edit) |
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Analysis of glycosylation and disulfide bonding of wild-type SARS-CoV-2 spike glycoprotein (edit) |
10.1101/2021.04.01.438120 |
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The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airways (edit) |
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Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry (edit) |
10.1101/2021.03.31.437960 |
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Crystallographic molecular replacement using an in silico-generated search model of SARS-CoV-2 ORF8 (edit) |
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The ORF8 protein of SARS-CoV-2 induced endoplasmic reticulum stress and mediated immune evasion by antagonizing production of interferon beta (edit) |
10.1016/J.VIRUSRES.2021.198350 |
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SARS-CoV-2 Nsp16 activation mechanism and a cryptic pocket with pan-coronavirus antiviral potential (edit) |
10.1016/J.BPJ.2021.03.024 |
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Multivalent binding of the partially disordered SARS-CoV-2 nucleocapsid phosphoprotein dimer to RNA (edit) |
10.1016/J.BPJ.2021.03.023 |
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The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA (edit) |
10.1038/S41467-021-21953-3 |
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Cathepsin L plays a key role in SARS-CoV-2 infection in humans and humanized mice and is a promising target for new drug development (edit) |
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The nucleotide addition cycle of the SARS-CoV-2 polymerase (edit) |
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Understanding the phase separation characteristics of nucleocapsid protein provides a new therapeutic opportunity against SARS-CoV-2 (edit) |
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SARS-CoV-2 M inhibitors with antiviral activity in a transgenic mouse model (edit) |
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Site-Specific O-Glycosylation Analysis of SARS-CoV-2 Spike Protein Produced in Insect and Human Cells (edit) |
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Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor (edit) |
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Functional analysis of SARS-CoV-2 proteins in Drosophila identifies Orf6-induced pathogenic effects with Selinexor as an effective treatment (edit) |
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In silico studies of selected multi-drug targeting against 3CLpro and nsp12 RNA-dependent RNA-polymerase proteins of SARS-CoV-2 and SARS-CoV (edit) |
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Arginine Methylation Regulates SARS-CoV-2 Nucleocapsid Protein Function and Viral Replication (edit) |
10.1101/2021.03.24.436822 |
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Topography, Spike Dynamics, and Nanomechanics of Individual Native SARS-CoV-2 Virions (edit) |
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Inhibition of HECT E3 ligases as potential therapy for COVID-19 (edit) |
10.1038/S41419-021-03513-1 |
| 2021-03-23 |
SARS-CoV-2 variants lacking ORF8 occurred in farmed mink and pangolin (edit) |
10.1016/J.GENE.2021.145596 |
| 2021-03-19 |
Mass spectrometric based detection of protein nucleotidylation in the RNA polymerase of SARS-CoV-2 (edit) |
10.1038/S42004-021-00476-4 |
| 2021-03-18 |
Sialic acid-Dependent Binding and Viral Entry of SARS-CoV-2 (edit) |
10.21203/RS.3.RS-318912/V1 |
| 2021-03-18 |
Identification of guanylyltransferase activity in the SARS-CoV-2 RNA polymerase (edit) |
10.1101/2021.03.17.435913 |
| 2021-03-16 |
Ca-dependent mechanism of membrane insertion and destabilization by the SARS-CoV-2 fusion peptide (edit) |
10.1016/J.BPJ.2021.02.023 |
| 2021-03-16 |
Neutrophil Elastase and Proteinase 3 Cleavage Sites Are Adjacent to the Polybasic Sequence within the Proteolytic Sensitive Activation Loop of the SARS-CoV-2 Spike Protein (edit) |
10.1021/ACSOMEGA.1C00363 |
| 2021-03-15 |
Unique and complementary suppression of cGAS-STING and RNA sensing- triggered innate immune responses by SARS-CoV-2 proteins (edit) |
10.1038/S41392-021-00515-5 |
| 2021-03-15 |
SARS-CoV-2 Nsp8 N-terminal domain dimerizes and harbors autonomously folded elements (edit) |
10.1101/2021.03.12.435186 |
| 2021-03-15 |
Structure, Mechanism and Crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase (edit) |
10.1101/2021.03.15.435326 |
| 2021-03-12 |
Contribution of SARS-CoV-2 accessory proteins to viral pathogenicity in K18 hACE2 transgenic mice (edit) |
10.1101/2021.03.09.434696 |
| 2021-03-11 |
New targets for drug design: importance of nsp14/nsp10 complex formation for the 3'-5' exoribonucleolytic activity on SARS-CoV-2 (edit) |
10.1111/FEBS.15815 |
| 2021-03-11 |
Immunoinformatic analysis of structural and epitope variations in the spike and Orf8 proteins of SARS-CoV-2/B.1.1.7 (edit) |
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| 2021-03-11 |
SARS-CoV-2 non-structural protein 13 (nsp13) hijacks host deubiquitinase USP13 and counteracts host antiviral immune response (edit) |
10.1038/S41392-021-00509-3 |
| 2021-03-10 |
Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies (edit) |
10.1016/J.CHOM.2021.02.003 |
| 2021-03-10 |
Genomic monitoring of SARS-CoV-2 uncovers an Nsp1 deletion variant that modulates type I interferon response (edit) |
10.1016/J.CHOM.2021.01.015 |
| 2021-03-08 |
Genome-wide CRISPR screening identifies TMEM106B as a proviral host factor for SARS-CoV-2 (edit) |
10.1038/S41588-021-00805-2 |
| 2021-03-05 |
Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2 (edit) |
10.1101/2021.03.05.434000 |
| 2021-03-05 |
RNA-dependent RNA polymerase (RdRp) inhibitors: The current landscape and repurposing for the COVID-19 pandemic (edit) |
10.1016/J.EJMECH.2021.113201 |
| 2021-03-03 |
Heterogeneity of Glycan Processing on Trimeric SARS-CoV-2 Spike Protein Revealed by Charge Detection Mass Spectrometry (edit) |
10.1021/JACS.1C00353 |
| 2021-03-03 |
The SARS-CoV-2 receptor-binding domain preferentially recognizes blood group A (edit) |
10.1182/BLOODADVANCES.2020003259 |
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SARS-CoV-2 Nucleocapsid Protein Targets RIG-I-Like Receptor Pathways to Inhibit the Induction of Interferon Response (edit) |
10.3390/CELLS10030530 |
| 2021-03-02 |
Enhanced Cholesterol-Dependent Hemifusion by Internal Fusion Peptide 1 of SARS Coronavirus-2 Compared to Its N-Terminal Counterpart (edit) |
10.1021/ACS.BIOCHEM.1C00046 |
| 2021-03-01 |
Dual inhibition of SARS-CoV-2 and human rhinovirus with protease inhibitors in clinical development (edit) |
10.1016/J.ANTIVIRAL.2021.105020 |
| 2021-03-01 |
Structural O-Glycoform Heterogeneity of the SARS-CoV-2 Spike Protein Receptor-Binding Domain Revealed by Native Top-Down Mass Spectrometry (edit) |
10.1101/2021.02.28.433291 |
| 2021-03-01 |
Ubiquitination of SARS-CoV-2 ORF7a promotes antagonism of interferon response (edit) |
10.1038/S41423-020-00603-6 |
| 2021-03-01 |
Structural insight reveals SARS-CoV-2 ORF7a as an immunomodulating factor for human CD14+ monocytes (edit) |
10.1016/J.ISCI.2021.102187 |
| 2021-03-01 |
Whole genome analysis of more than 10 000 SARS-CoV-2 virus unveils global genetic diversity and target region of NSP6 (edit) |
10.1093/BIB/BBAB025 |
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Hallmarks of Alpha- and Betacoronavirus non-structural protein 7+8 complexes (edit) |
10.1126/SCIADV.ABF1004 |
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TMPRSS11D and TMPRSS13 Activate the SARS-CoV-2 Spike Protein (edit) |
10.3390/V13030384 |
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SARS-CoV-2 Nonstructural Proteins 1 and 13 Suppress Caspase-1 and the NLRP3 Inflammasome Activation (edit) |
10.3390/MICROORGANISMS9030494 |
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SARS-CoV-2 nsp12 attenuates type I interferon production by inhibiting IRF3 nuclear translocation (edit) |
10.1038/S41423-020-00619-Y |
| 2021-02-24 |
A Biochemical Perspective of the Nonstructural Proteins (NSPs) and the Spike Protein of SARS CoV-2 (edit) |
10.1007/S10930-021-09967-8 |
| 2021-02-24 |
SARS-CoV-2 genomic surveillance identifies naturally occurring truncations of ORF7a that limit immune suppression (edit) |
10.1101/2021.02.22.21252253 |
| 2021-02-24 |
SARS-CoV-2 ORF6 disturbs nucleocytoplasmic trafficking to advance the viral replication (edit) |
10.1101/2021.02.24.432656 |
| 2021-02-23 |
The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation (edit) |
10.1101/2021.02.23.432450 |
| 2021-02-23 |
Structural and functional characterization of SARS-CoV-2 RBD domains produced in mammalian cells (edit) |
10.1101/2021.02.23.432424 |
| 2021-02-22 |
Identification and functional analysis of the SARS-COV-2 nucleocapsid protein (edit) |
10.1186/S12866-021-02107-3 |
| 2021-02-22 |
ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation (edit) |
10.1016/J.DEVCEL.2020.12.010 |
| 2021-02-19 |
Probing the SAM Binding Site of SARS-CoV-2 nsp14 in vitro Using SAM Competitive Inhibitors Guides Developing Selective bi-substrate Inhibitors (edit) |
10.1101/2021.02.19.424337 |
| 2021-02-18 |
SARS-CoV-2 nucleocapsid protein dually regulates innate immune responses (edit) |
10.1101/2021.02.17.431755 |
| 2021-02-18 |
Direct activation of endothelial cells by SARS-CoV-2 nucleocapsid protein is blocked by Simvastatin (edit) |
10.1101/2021.02.14.431174 |
| 2021-02-12 |
Proteolytic Activation of SARS-CoV-2 Spike at the S1/S2 Boundary: Potential Role of Proteases beyond Furin (edit) |
10.1021/ACSINFECDIS.0C00701 |
| 2021-02-11 |
Identification of ebselen and its analogues as potent covalent inhibitors of papain-like protease from SARS-CoV-2 (edit) |
10.1038/S41598-021-83229-6 |
| 2021-02-11 |
A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry (edit) |
10.1038/S41467-021-21213-4 |
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Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2 (edit) |
10.1038/S42003-021-01735-9 |
| 2021-02-09 |
Energetic and structural features of SARS-CoV-2 N-protein co-assemblies with nucleic acids (edit) |
10.1101/2021.02.08.430344 |
| 2021-02-09 |
Dynamic competition between SARS-CoV-2 NSP1 and mRNA on the human ribosome inhibits translation initiation (edit) |
10.1073/PNAS.2017715118 |
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Coronavirus replication-transcription complex: Vital and selective NMPylation of a conserved site in nsp9 by the NiRAN-RdRp subunit (edit) |
10.1073/PNAS.2022310118 |
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SARS-CoV-2 S protein:ACE2 interaction reveals novel allosteric targets (edit) |
10.7554/ELIFE.63646 |
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Targeting CTP Synthetase 1 to Restore Interferon Induction and Impede Nucleotide Synthesis in SARS-CoV-2 Infection (edit) |
10.1101/2021.02.05.429959 |
| 2021-02-05 |
Protein glycosylation is essential for SARS-CoV-2 infection (edit) |
10.1101/2021.02.05.429940 |
| 2021-02-05 |
SARS-CoV-2 ORF7b: is a bat virus protein homologue a major cause of COVID-19 symptoms? (edit) |
10.1101/2021.02.05.428650 |
| 2021-02-04 |
Targeted in situ cross-linking mass spectrometry and integrative modeling reveal the architectures of Nsp1, Nsp2, and Nucleocapsid proteins from SARS-CoV-2 (edit) |
10.1101/2021.02.04.429751 |
| 2021-02-02 |
Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors (edit) |
10.1038/S41467-021-21060-3 |
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Mechanisms of Coronavirus Nsp1-Mediated Control of Host and Viral Gene Expression (edit) |
10.3390/CELLS10020300 |
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Mn2+ coordinates Cap-0-RNA to align substrates for efficient 2′-O-methyl transfer by SARS-CoV-2 nsp16 (edit) |
10.1101/2021.01.31.429023 |
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SARS-CoV-2 spike protein S1 subunit induces pro-inflammatory responses via toll-like receptor 4 signaling in murine and human macrophages (edit) |
10.1016/J.HELIYON.2021.E06187 |
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Multimerization- and glycosylation-dependent receptor binding of SARS-CoV-2 spike proteins (edit) |
10.1371/JOURNAL.PPAT.1009282 |
| 2021-02-01 |
Cold sensitivity of the SARS-CoV-2 spike ectodomain (edit) |
10.1038/S41594-020-00547-5 |
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SARS-CoV-2 ORF9b inhibits RIG-I-MAVS antiviral signaling by interrupting K63-linked ubiquitination of NEMO (edit) |
10.1016/J.CELREP.2021.108761 |
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Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression (edit) |
10.1126/SCIADV.ABE7386 |
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Structural Basis of SARS-CoV-2 Polymerase Inhibition by Favipiravir (edit) |
10.1016/J.XINN.2021.100080 |
| 2021-02-01 |
Force-Dependent Stimulation of RNA Unwinding by SARS-CoV-2 NSP13 Helicase (edit) |
10.1016/J.BPJ.2020.11.772 |
| 2021-01-29 |
RNA-dependent RNA polymerase: Structure, mechanism, and drug discovery for COVID-19 (edit) |
10.1016/J.BBRC.2020.08.116 |
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A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication (edit) |
10.1038/S41467-021-20900-6 |
| 2021-01-28 |
D614G Substitution of SARS-CoV-2 Spike Protein Increases Syncytium Formation and Viral Transmission via Enhanced Furin-mediated Spike Cleavage (edit) |
10.1101/2021.01.27.428541 |
| 2021-01-27 |
Cryo-EM structures of the SARS-CoV-2 endoribonuclease Nsp15 reveal insight into nuclease specificity and dynamics (edit) |
10.1038/S41467-020-20608-Z |
| 2021-01-25 |
Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis (edit) |
10.1038/S41586-021-03237-4 |
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In silico evaluation of lapachol derivatives binding to the Nsp9 of SARS-CoV-2 (edit) |
10.1080/07391102.2021.1875050 |
| 2021-01-21 |
SARS-CoV-2 nucleocapsid protein undergoes liquid-liquid phase separation into stress granules through its N-terminal intrinsically disordered region (edit) |
10.1038/S41421-020-00240-3 |
| 2021-01-21 |
The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein (edit) |
10.1038/S41467-020-20768-Y |
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Insight into molecular characteristics of SARS-CoV-2 spike protein following D614G point mutation, a molecular dynamics study (edit) |
10.1080/07391102.2021.1872418 |
| 2021-01-20 |
The complex structure of GRL0617 and SARS-CoV-2 PLpro reveals a hot spot for antiviral drug discovery (edit) |
10.1038/S41467-020-20718-8 |
| 2021-01-20 |
Biological and Clinical Consequences of Integrin Binding via a Rogue RGD Motif in the SARS CoV-2 Spike Protein (edit) |
10.3390/V13020146 |
| 2021-01-18 |
Fluorescent Glycan Fingerprinting of SARS2 Spike Proteins (edit) |
10.1101/2021.01.16.426965 |
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Nucleocapsid and Spike Proteins of the Coronavirus SARS-CoV-2 Induce IL6 in Monocytes and Macrophages-Potential Implications for Cytokine Storm Syndrome (edit) |
10.3390/VACCINES9010054 |
| 2021-01-12 |
Structural Insight Into the SARS-CoV-2 Nucleocapsid Protein C-Terminal Domain Reveals a Novel Recognition Mechanism for Viral Transcriptional Regulatory Sequences (edit) |
10.3389/FCHEM.2020.624765 |
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Snake venom phospholipases A2 possess a strong virucidal activity against SARS-CoV-2 in vitro and block the cell fusion mediated by spike glycoprotein interaction with the ACE2 receptor (edit) |
10.1101/2021.01.12.426042 |
| 2021-01-12 |
Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis (edit) |
10.1021/ACSOMEGA.0C03512 |
| 2021-01-11 |
No evidence for basigin/CD147 as a direct SARS-CoV-2 spike binding receptor (edit) |
10.1038/S41598-020-80464-1 |
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Stabilizing the closed SARS-CoV-2 spike trimer (edit) |
10.1038/S41467-020-20321-X |
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Functional Analysis of SARS-CoV-2 Proteins in Drosophila Identifies Orf6-induced Pathogenicity Attenuated by Selinexor (edit) |
10.21203/RS.3.RS-141269/V1 |
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AXL is a candidate receptor for SARS-CoV-2 that promotes infection of pulmonary and bronchial epithelial cells (edit) |
10.1038/S41422-020-00460-Y |
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New targets for drug design: Importance of nsp14/nsp10 complex formation for the 3’-5’ exoribonucleolytic activity on SARS-CoV-2 (edit) |
10.1101/2021.01.07.425745 |
| 2021-01-06 |
N- and O-Glycosylation of the SARS-CoV-2 Spike Protein (edit) |
10.1021/ACS.ANALCHEM.0C03173 |
| 2021-01-03 |
Recent advancements in glycoproteomic studies: Glycopeptide enrichment and derivatization, characterization of glycosylation in SARS CoV2, and interacting glycoproteins (edit) |
10.1002/MAS.21679 |
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Spatial and temporal roles of SARS-CoV PLpro -A snapshot (edit) |
10.1096/FJ.202002271 |
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Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs (edit) |
10.1016/J.MCPRO.2021.100120 |
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SARS-CoV-2 nucleocapsid protein phase separates with G3BPs to disassemble stress granules and facilitate viral production (edit) |
10.1016/J.SCIB.2021.01.013 |
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SARS-CoV-2 N Protein Induces Acute Lung Injury in Mice NF-ĸB Activation (edit) |
10.3389/FIMMU.2021.791753 |
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SARS-CoV-2 main protease suppresses type I interferon production by preventing nuclear translocation of phosphorylated IRF3 (edit) |
10.7150/IJBS.59943 |
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Human Surfactant Protein D Binds Spike Protein and Acts as an Entry Inhibitor of SARS-CoV-2 Pseudotyped Viral Particles (edit) |
10.3389/FIMMU.2021.641360 |
| 2021-01-01 |
Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion (edit) |
10.1371/JOURNAL.PPAT.1009246 |
| 2021-01-01 |
The Case for S2: The Potential Benefits of the S2 Subunit of the SARS-CoV-2 Spike Protein as an Immunogen in Fighting the COVID-19 Pandemic (edit) |
10.3389/FIMMU.2021.637651 |
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Glycans of SARS-CoV-2 Spike Protein in Virus Infection and Antibody Production (edit) |
10.3389/FMOLB.2021.629873 |
| 2021-01-01 |
Heparan Sulfate Facilitates Spike Protein-Mediated SARS-CoV-2 Host Cell Invasion and Contributes to Increased Infection of SARS-CoV-2 G614 Mutant and in Lung Cancer (edit) |
10.3389/FMOLB.2021.649575 |
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SARS-CoV-2 Spike Protein Induces Degradation of Junctional Proteins That Maintain Endothelial Barrier Integrity (edit) |
10.3389/FCVM.2021.687783 |
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SARS-CoV-2 variants with mutations at the S1/S2 cleavage site are generated in vitro during propagation in TMPRSS2-deficient cells (edit) |
10.1371/JOURNAL.PPAT.1009233 |
| 2021-01-01 |
The Importance of Glycosylation in COVID-19 Infection (edit) |
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O-Glycosylation Landscapes of SARS-CoV-2 Spike Proteins (edit) |
10.3389/FCHEM.2021.689521 |
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Site-Specific Glycosylation Patterns of the SARS-CoV-2 Spike Protein Derived From Recombinant Protein and Viral WA1 and D614G Strains (edit) |
10.3389/FCHEM.2021.767448 |
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Metformin Suppresses Monocyte Immunometabolic Activation by SARS-CoV-2 Spike Protein Subunit 1 (edit) |
10.3389/FIMMU.2021.733921 |
| 2021-01-01 |
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Membrane (M) and Spike (S) Proteins Antagonize Host Type I Interferon Response (edit) |
10.3389/FCIMB.2021.766922 |
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Cholesterol-Rich Lipid Rafts as Platforms for SARS-CoV-2 Entry (edit) |
10.3389/FIMMU.2021.796855 |
| 2021-01-01 |
Dependence of SARS-CoV-2 infection on cholesterol-rich lipid raft and endosomal acidification (edit) |
10.1016/J.CSBJ.2021.04.001 |
| 2021-01-01 |
COVID-19 and Toll-Like Receptor 4 (TLR4): SARS-CoV-2 May Bind and Activate TLR4 to Increase ACE2 Expression, Facilitating Entry and Causing Hyperinflammation (edit) |
10.1155/2021/8874339 |
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SARS-CoV-2 Spike Antagonizes Innate Antiviral Immunity by Targeting Interferon Regulatory Factor 3 (edit) |
10.3389/FCIMB.2021.789462 |
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SARS-CoV-2 uses major endothelial integrin αvβ3 to cause vascular dysregulation in-vitro during COVID-19 (edit) |
10.1371/JOURNAL.PONE.0253347 |
| 2021-01-01 |
ORF3a-Mediated Incomplete Autophagy Facilitates Severe Acute Respiratory Syndrome Coronavirus-2 Replication (edit) |
10.3389/FCELL.2021.716208 |
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SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1 (edit) |
10.3389/FIMMU.2021.662989 |
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The Landscape of Aminoacyl-tRNA Synthetases Involved in Severe Acute Respiratory Syndrome Coronavirus 2 Infection (edit) |
10.3389/FPHYS.2021.818297 |
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Overexpression of SARS-CoV-2 protein ORF6 dislocates RAE1 and NUP98 from the nuclear pore complex (edit) |
10.1016/J.BBRC.2020.11.115 |
| 2021-01-01 |
The Functional Classification of ORF8 in SARS-CoV-2 Replication, Immune Evasion, and Viral Pathogenesis Inferred through Phylogenetic Profiling (edit) |
10.1177/11769343211003079 |
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SARS-CoV-2 ORF8 Forms Intracellular Aggregates and Inhibits IFNγ-Induced Antiviral Gene Expression in Human Lung Epithelial Cells (edit) |
10.3389/FIMMU.2021.679482 |
| 2021-01-01 |
Structure of SARS-CoV-2 ORF8, a rapidly evolving immune evasion protein (edit) |
10.1073/PNAS.2021785118 |
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RIG-I-Like Receptor-Mediated Recognition of Viral Genomic RNA of Severe Acute Respiratory Syndrome Coronavirus-2 and Viral Escape From the Host Innate Immune Responses (edit) |
10.3389/FIMMU.2021.700926 |
| 2021-01-01 |
SARS-CoV-2 Accessory Protein ORF7b Mediates Tumor Necrosis Factor-α-Induced Apoptosis in Cells (edit) |
10.3389/FMICB.2021.654709 |
| 2021-01-01 |
Structural Analysis of SARS-CoV-2 ORF8 Protein: Pathogenic and Therapeutic Implications (edit) |
10.3389/FGENE.2021.693227 |
| 2021-01-01 |
SARS-CoV-2 NSP1 C-terminal (residues 131–180) is an intrinsically disordered region in isolation (edit) |
10.1016/J.CRVIRO.2021.100007 |
| 2021-01-01 |
SARS-CoV-2 viral proteins NSP1 and NSP13 inhibit interferon activation through distinct mechanisms (edit) |
10.1371/JOURNAL.PONE.0253089 |
| 2021-01-01 |
Coronavirus Nsp1: Immune Response Suppression and Protein Expression Inhibition (edit) |
10.3389/FMICB.2021.752214 |
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A novel virtual screening procedure identifies Pralatrexate as inhibitor of SARS-CoV-2 RdRp and it reduces viral replication in vitro (edit) |
10.1371/JOURNAL.PCBI.1008489 |
| 2020-12-30 |
SARS-CoV-2 Nucleocapsid Protein Interacts with RIG-I and Represses RIG-Mediated IFN-β Production (edit) |
10.3390/V13010047 |
| 2020-12-29 |
SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species (edit) |
10.1080/22221751.2020.1870414 |
| 2020-12-29 |
Environmental Dependence of the Structure of the C-terminal Domain of the SARS-CoV-2 Envelope Protein (edit) |
10.1101/2020.12.29.424646 |
| 2020-12-28 |
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling (edit) |
10.1038/S41392-020-00438-7 |
| 2020-12-26 |
D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction (edit) |
10.1016/J.CELREP.2020.108630 |
| 2020-12-26 |
Genomic diversity of SARS-CoV-2 can be accelerated by a mutation in the nsp14 gene (edit) |
10.1101/2020.12.23.424231 |
| 2020-12-23 |
Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin (edit) |
10.1055/S-0040-1721319 |
| 2020-12-23 |
Host Cell Proteases Drive Early or Late SARS-CoV-2 Penetration (edit) |
10.1101/2020.12.22.423906 |
| 2020-12-21 |
Fatty Acid Synthase inhibition prevents palmitoylation of SARS-CoV2 Spike Protein and improves survival of mice infected with murine hepatitis virus (edit) |
10.1101/2020.12.20.423603 |
| 2020-12-20 |
Implications of Spike-glycoprotein processing at S1/S2 by Furin, at S2’ by Furin and/or TMPRSS2 and shedding of ACE2: cell-to-cell fusion, cell entry and infectivity of SARS-CoV-2 (edit) |
10.1101/2020.12.18.423106 |
| 2020-12-16 |
Subtle influence of ACE2 glycan processing on SARS-CoV-2 recognition (edit) |
10.1016/J.JMB.2020.166762 |
| 2020-12-16 |
The S1 protein of SARS-CoV-2 crosses the blood–brain barrier in mice (edit) |
10.1038/S41593-020-00771-8 |
| 2020-12-16 |
Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase (edit) |
10.1016/J.BPJ.2020.11.2276 |
| 2020-12-11 |
High-Throughput Screening and Quantum Mechanics for Identifying Potent Inhibitors against Mac1 Domain of SARS-CoV-2 Nsp3 (edit) |
10.1109/TCBB.2020.3037136 |
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Spike glycoprotein and host cell determinants of SARS-CoV-2 entry and cytopathic effects (edit) |
10.1128/JVI.02304-20 |
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SARS-CoV-2 Nsp16 activation mechanism and a cryptic pocket with pan-coronavirus antiviral potential (edit) |
10.1101/2020.12.10.420109 |
| 2020-12-10 |
The SARS-CoV-2 ORF10 is not essential in vitro or in vivo in humans (edit) |
10.1371/JOURNAL.PPAT.1008959 |
| 2020-12-09 |
Real-Time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles (edit) |
10.1016/J.CHOM.2020.11.001 |
| 2020-12-09 |
Ritonavir may inhibit exoribonuclease activity of nsp14 from the SARS-CoV-2 virus and potentiate the activity of chain terminating drugs (edit) |
10.1016/J.IJBIOMAC.2020.12.038 |
| 2020-12-07 |
SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cells (edit) |
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An insight into SARS-CoV-2 Membrane protein interaction with Spike, Envelope, and Nucleocapsid proteins (edit) |
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Binding mechanism and structural insights into the identified protein target of COVID-19 and importin-α with in-vitro effective drug ivermectin (edit) |
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Remdesivir targets a structurally analogous region of the Ebola virus and SARS-CoV-2 polymerases (edit) |
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Mass Spectrometry Analysis of Newly Emerging Coronavirus HCoV-19 Spike Protein and Human ACE2 Reveals Camouflaging Glycans and Unique Post-Translational Modifications (edit) |
10.1016/J.ENG.2020.07.014 |
| 2020-08-29 |
The SARS-CoV-2 ORF10 is not essential in vitro or in vivo in humans (edit) |
10.1101/2020.08.29.257360 |
| 2020-08-28 |
In silico structure modelling of SARS-CoV-2 Nsp13 helicase and Nsp14 and repurposing of FDA approved antiviral drugs as dual inhibitors (edit) |
10.1016/J.GENREP.2020.100860 |
| 2020-08-27 |
SARS-CoV-2 Nucleocapsid protein is decorated with multiple N- and O-glycans (edit) |
10.1101/2020.08.26.269043 |
| 2020-08-27 |
Structure of SARS-CoV-2 ORF8, a rapidly evolving coronavirus protein implicated in immune evasion (edit) |
10.1101/2020.08.27.270637 |
| 2020-08-26 |
Room Temperature Structure of SARS-CoV-2 Nsp10/Nsp16 Methyltransferase in a Complex with m7GpppA Cap-0 and SAM Determined by Fixed-Target Serial Crystallography (edit) |
10.2210/PDB7JPE/PDB |
| 2020-08-26 |
Room Temperature Crystal Structure of Nsp10/Nsp16 from SARS-CoV-2 with Substrates and Products of 2'-O-methylation of the Cap-1 (edit) |
10.2210/PDB7JIB/PDB |
| 2020-08-26 |
Room Temperature Structure of SARS-CoV-2 Nsp10/Nsp16 Methyltransferase in a Complex with 2'-O-methylated m7GpppA Cap-1 and SAH Determined by Fixed-Target Serial Crystallography (edit) |
10.2210/PDB7JHE/PDB |
| 2020-08-26 |
Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2 (edit) |
10.15252/EMBJ.2020106275 |
| 2020-08-26 |
SARS-CoV-2 Spike 1 Protein Controls Natural Killer Cell Activation via the HLA-E/NKG2A Pathway (edit) |
10.3390/CELLS9091975 |
| 2020-08-26 |
Crystal Structure of SARS-CoV-2 NSP7-NSP8 complex (edit) |
10.2210/PDB7JLT/PDB |
| 2020-08-25 |
The S1/S2 boundary of SARS-CoV-2 spike protein modulates cell entry pathways and transmission (edit) |
10.1101/2020.08.25.266775 |
| 2020-08-24 |
In silico validation of coumarin derivatives as potential inhibitors against Main Protease, NSP10/NSP16-Methyltransferase, Phosphatase and Endoribonuclease of SARS CoV-2 (edit) |
10.1080/07391102.2020.1808075 |
| 2020-08-24 |
The SARS-CoV-2 Envelope and Membrane proteins modulate maturation and retention of the Spike protein, allowing optimal formation of VLPs in presence of Nucleoprotein (edit) |
10.1101/2020.08.24.260901 |
| 2020-08-24 |
Dynamics of the N-terminal domain of SARS-CoV-2 nucleocapsid protein drives dsRNA melting in a counterintuitive tweezer-like mechanism (edit) |
10.1101/2020.08.24.264465 |
| 2020-08-24 |
Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor (edit) |
10.1016/J.CHOM.2020.08.004 |
| 2020-08-24 |
SARS-CoV-2 Spike protein co-opts VEGF-A/Neuropilin-1 receptor signaling to induce analgesia (edit) |
10.1101/2020.07.17.209288 |
| 2020-08-24 |
Pathogenicity, immunogenicity, and protective ability of an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction of the spike protein (edit) |
10.1101/2020.08.24.264192 |
| 2020-08-21 |
Dynamic competition between SARS-CoV-2 NSP1 and mRNA on the human ribosome inhibits translation initiation (edit) |
10.1101/2020.08.20.259770 |
| 2020-08-20 |
SARS-CoV-2 ORF8 and SARS-CoV ORF8ab: Genomic Divergence and Functional Convergence (edit) |
10.3390/PATHOGENS9090677 |
| 2020-08-20 |
Structural basis for the multimerization of nonstructural protein nsp9 from SARS-CoV-2 (edit) |
10.1186/S43556-020-00005-0 |
| 2020-08-19 |
SARS-CoV-2 ORF9c Is a Membrane-Associated Protein that Suppresses Antiviral Responses in Cells (edit) |
10.1101/2020.08.18.256776 |
| 2020-08-18 |
In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges (edit) |
10.1126/SCIENCE.ABD5223 |
| 2020-08-18 |
Vitamin B12 may inhibit RNA-dependent-RNA polymerase activity of nsp12 from the SARS-CoV-2 virus (edit) |
10.1002/IUB.2359 |
| 2020-08-17 |
Structures and distributions of SARS-CoV-2 spike proteins on intact virions (edit) |
10.1038/S41586-020-2665-2 |
| 2020-08-17 |
ORF8 and ORF3b antibodies are accurate serological markers of early and late SARS-CoV-2 infection (edit) |
10.1038/S41590-020-0773-7 |
| 2020-08-17 |
SARS-CoV-2 ORF9b Antagonizes Type I and III Interferons by Targeting Multiple Components of RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING Signaling Pathways (edit) |
10.1101/2020.08.16.252973 |
| 2020-08-14 |
Methylation of RNA Cap in SARS-CoV-2 captured by serial crystallography (edit) |
10.1101/2020.08.14.251421 |
| 2020-08-14 |
The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid phosphorylation and inhibits viral infection in vitro (edit) |
10.1101/2020.08.14.251207 |
| 2020-08-14 |
Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion (edit) |
10.1101/2020.08.13.243303 |
| 2020-08-14 |
1H, 13C, and 15N backbone chemical shift assignments of the apo and the ADP-ribose bound forms of the macrodomain of SARS-CoV-2 non-structural protein 3b (edit) |
10.1007/S12104-020-09973-4 |
| 2020-08-13 |
Characterisation of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification (edit) |
10.1101/2020.08.13.248211 |
| 2020-08-13 |
The use of knowledge management tools in viroinformatics. Example study of a highly conserved sequence motif in Nsp3 of SARS-CoV-2 as a therapeutic target (edit) |
10.1016/J.COMPBIOMED.2020.103963 |
| 2020-08-13 |
Maraviroc inhibits SARS-CoV-2 multiplication and s-protein mediated cell fusion in cell culture (edit) |
10.1101/2020.08.12.246389 |
| 2020-08-12 |
Structural insight into the role of novel SARS-CoV-2 E protein: A potential target for vaccine development and other therapeutic strategies (edit) |
10.1371/JOURNAL.PONE.0237300 |
| 2020-08-12 |
Suppression of MDA5-mediated antiviral immune responses by NSP8 of SARS-CoV-2 (edit) |
10.1101/2020.08.12.247767 |
| 2020-08-11 |
Cryo-EM Structures of the SARS-CoV-2 Endoribonuclease Nsp15 (edit) |
10.1101/2020.08.11.244863 |
| 2020-08-11 |
In Silico Identification of Potential Inhibitors of ADP-Ribose Phosphatase of SARS-CoV-2 nsP3 by Combining E-Pharmacophore- and Receptor-Based Virtual Screening of Database (edit) |
10.1002/SLCT.202001419 |
| 2020-08-11 |
Growth Factor Receptor Signaling Inhibition Prevents SARS-CoV-2 Replication (edit) |
10.1016/J.MOLCEL.2020.08.006 |
| 2020-08-11 |
Mutational spectra of SARS-CoV-2 orf1ab polyprotein and signature mutations in the United States of America (edit) |
10.1002/JMV.26417 |
| 2020-08-10 |
Repurposing of SARS-CoV nucleocapsid protein specific nuclease resistant RNA aptamer for therapeutics against SARS-CoV-2 (edit) |
10.1016/J.MEEGID.2020.104497 |
| 2020-08-10 |
DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist (edit) |
10.1101/2020.08.09.242917 |
| 2020-08-10 |
Discovery of COVID-19 Inhibitors Targeting the SARS-CoV2 Nsp13 Helicase (edit) |
10.1101/2020.08.09.243246 |
| 2020-08-09 |
Mass Spectrometric detection of SARS-CoV-2 virus in scrapings of the epithelium of the nasopharynx of infected patients via Nucleocapsid N protein (edit) |
10.1021/ACS.JPROTEOME.0C00412 |
| 2020-08-07 |
Epigallocatechin gallate and theaflavin gallate interaction in SARS-CoV-2 spike-protein central channel with reference to the hydroxychloroquine interaction: Bioinformatics and molecular docking study (edit) |
10.1002/DDR.21730 |
| 2020-08-06 |
Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors (edit) |
10.1101/2020.08.06.240192 |
| 2020-08-06 |
Structural characterization of the C-terminal domain of SARS-CoV-2 nucleocapsid protein (edit) |
10.1186/S43556-020-00001-4 |
| 2020-08-05 |
Intra- and intermolecular atomic-scale interactions in the receptor binding domain of SARS-CoV-2 spike protein: implication for ACE2 receptor binding (edit) |
10.1039/D0CP03145C |
| 2020-08-05 |
Structure of Furin Protease Binding to SARS-CoV-2 Spike Glycoprotein and Implications for Potential Targets and Virulence (edit) |
10.1021/ACS.JPCLETT.0C01698 |
| 2020-08-04 |
SARS-CoV-2 nucleocapsid and Nsp3 binding: an in silico study (edit) |
10.1007/S00203-020-01998-6 |
| 2020-08-04 |
Deciphering the protein motion of S1 subunit in SARS-CoV-2 spike glycoprotein through integrated computational methods (edit) |
10.1080/07391102.2020.1802338 |
| 2020-08-04 |
Role of key point Mutations in Receptor Binding Domain of SARS-CoV-2 Spike Glycoprotein (edit) |
10.2174/1871526520666200804161650 |
| 2020-08-04 |
Enhanced Binding of SARS-CoV-2 Spike Protein to Receptor by Distal Polybasic Cleavage Sites (edit) |
10.1021/ACSNANO.0C04798 |
| 2020-08-03 |
Identification of promising drug candidates against NSP16 of SARS-CoV-2 through computational drug repurposing study (edit) |
10.1080/07391102.2020.1802349 |
| 2020-08-03 |
Structure of SARS-CoV-2 2′-O-methyltransferase heterodimer with RNA Cap analog and sulfates bound reveals new strategies for structure-based inhibitor design (edit) |
10.1101/2020.08.03.234716 |
| 2020-08-03 |
SARS-CoV-2 ORF6 disrupts nucleocytoplasmic transport through interactions with Rae1 and Nup98 (edit) |
10.1101/2020.08.03.234559 |
| 2020-08-02 |
A Systemic and Molecular Study of Subcellular Localization of SARS-CoV-2 Proteins (edit) |
10.1101/2020.08.02.233023 |
| 2020-08-01 |
In Silico Screening of Potential Spike Glycoprotein Inhibitors of SARS-CoV-2 with Drug Repurposing Strategy (edit) |
10.1007/S11655-020-3427-6 |
| 2020-08-01 |
Genomic variance of Open Reading Frames (ORFs) and Spike protein in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (edit) |
10.1097/JCMA.0000000000000387 |
| 2020-07-31 |
Antibody response against SARS-CoV-2 spike protein and nucleoprotein evaluated by 4 automated immunoassays and 3 ELISAs (edit) |
10.1016/J.CMI.2020.07.038 |
| 2020-07-31 |
The SARS-CoV-2 Nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein (edit) |
10.1101/2020.07.30.228023 |
| 2020-07-31 |
A thermostable, closed SARS-CoV-2 spike protein trimer (edit) |
10.1038/S41594-020-0478-5 |
| 2020-07-31 |
Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase (edit) |
10.1101/2020.07.31.231274 |
| 2020-07-30 |
Substrate specificity of SARS-CoV-2 nsp10-nsp16 methyltransferase (edit) |
10.1101/2020.07.30.228478 |
| 2020-07-30 |
Transcriptome & viral growth analysis of SARS-CoV-2-infected Vero CCL-81 cells (edit) |
10.4103/IJMR.IJMR_2257_20 |
| 2020-07-30 |
A dynamic regulatory interface on SARS-CoV-2 RNA polymerase (edit) |
10.1101/2020.07.30.229187 |
| 2020-07-29 |
Crystal structure of SARS-CoV-2 nsp10/nsp16 2'-O-methylase and its implication on antiviral drug design (edit) |
10.1038/S41392-020-00241-4 |
| 2020-07-29 |
Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity (edit) |
10.1038/S41586-020-2601-5 |
| 2020-07-29 |
SARS-CoV-2 Orf9b suppresses type I interferon responses by targeting TOM70 (edit) |
10.1038/S41423-020-0514-8 |
| 2020-07-28 |
Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein (edit) |
10.1186/S13073-020-00763-0 |
| 2020-07-28 |
Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex (edit) |
10.1016/J.CELL.2020.07.033 |
| 2020-07-27 |
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Membrane (M) Protein Inhibits Type I and III Interferon Production by Targeting RIG-I/MDA-5 Signaling (edit) |
10.1101/2020.07.26.222026 |
| 2020-07-26 |
No evidence for basigin/CD147 as a direct SARS-CoV-2 spike binding receptor (edit) |
10.1101/2020.07.25.221036 |
| 2020-07-24 |
Structural basis of RNA cap modification by SARS-CoV-2 (edit) |
10.1038/S41467-020-17496-8 |
| 2020-07-24 |
Identification, Mapping and Relative Quantitation of SARS-CoV-2 Spike Glycopeptides by Mass-Retention Time Fingerprinting (edit) |
10.1101/2020.07.24.217562 |
| 2020-07-24 |
Computational drug repurposing for the identification of SARS-CoV-2 main protease inhibitors (edit) |
10.1080/07391102.2020.1796805 |
| 2020-07-24 |
SARS-CoV-2 ORF8 and SARS-CoV ORF8ab: Genomic Divergence and Functional Convergence (edit) |
10.20944/PREPRINTS202007.0587.V1 |
| 2020-07-23 |
TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells (edit) |
10.26508/LSA.202000786 |
| 2020-07-22 |
Linear B-cell epitopes in the spike and nucleocapsid proteins as markers of SARS-CoV-2 exposure and disease severity (edit) |
10.1016/J.EBIOM.2020.102911 |
| 2020-07-22 |
Controlling the SARS-CoV-2 spike glycoprotein conformation (edit) |
10.1038/S41594-020-0479-4 |
| 2020-07-21 |
Distinct conformational states of SARS-CoV-2 spike protein (edit) |
10.1126/SCIENCE.ABD4251 |
| 2020-07-18 |
Structural basis for the inhibition of the papain-like protease of SARS-CoV-2 by small molecules (edit) |
10.1101/2020.07.17.208959 |
| 2020-07-17 |
Crystal structures of SARS-CoV-2 ADP-ribose phosphatase: from the apo form to ligand complexes (edit) |
10.1107/S2052252520009653 |
| 2020-07-17 |
Cryo-EM analysis of the post-fusion structure of the SARS-CoV spike glycoprotein (edit) |
10.1038/S41467-020-17371-6 |
| 2020-07-17 |
Natural Polymorphisms Are Present in the Furin Cleavage Site of the SARS-CoV-2 Spike Glycoprotein (edit) |
10.3389/FGENE.2020.00783 |
| 2020-07-17 |
Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2 (edit) |
10.1126/SCIENCE.ABC8665 |
| 2020-07-15 |
Bivalent binding of a fully human IgG to the SARS-CoV-2 spike proteins reveals mechanisms of potent neutralization (edit) |
10.1101/2020.07.14.203414 |
| 2020-07-15 |
A putative new SARS-CoV protein, 3c, encoded in an ORF overlapping ORF3a (edit) |
10.1099/JGV.0.001469 |
| 2020-07-13 |
Cold sensitivity of the SARS-CoV-2 spike ectodomain (edit) |
10.1101/2020.07.12.199588 |
| 2020-07-13 |
Identification of potential drugs against SARS-CoV-2 non-structural protein 1 (nsp1) (edit) |
10.1080/07391102.2020.1792992 |
| 2020-07-13 |
Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex (edit) |
10.1101/2020.07.08.194084 |
| 2020-07-12 |
Architecture and self-assembly of the SARS-CoV-2 nucleocapsid protein (edit) |
10.1002/PRO.3909 |
| 2020-07-10 |
Stabilizing the Closed SARS-CoV-2 Spike Trimer (edit) |
10.1101/2020.07.10.197814 |
| 2020-07-09 |
Molecular architecture of the SARS-CoV-2 virus (edit) |
10.1101/2020.07.08.192104 |
| 2020-07-09 |
Characterization of heparin and severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) spike glycoprotein binding interactions (edit) |
10.1016/J.ANTIVIRAL.2020.104873 |
| 2020-07-09 |
Decline of humoral responses against SARS-CoV-2 Spike in convalescent individuals (edit) |
10.1101/2020.07.09.194639 |
| 2020-07-08 |
Room Temperature Structure of SARS-CoV-2 NSP10/NSP16 Methyltransferase in a Complex with SAM Determined by Fixed-Target Serial Crystallography (edit) |
10.2210/PDB6XKM/PDB |
| 2020-07-07 |
SARS-CoV-2 Nsp1 binds ribosomal mRNA channel to inhibit translation (edit) |
10.1101/2020.07.07.191676 |
| 2020-07-06 |
Discovery of Drug-like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3 (edit) |
10.1101/2020.07.06.190413 |
| 2020-07-06 |
N and O glycosylation of the SARS-CoV-2 spike protein (edit) |
10.1101/2020.07.05.187344 |
| 2020-07-04 |
A pH-dependent switch mediates conformational masking of SARS-CoV-2 spike (edit) |
10.1101/2020.07.04.187989 |
| 2020-07-03 |
Tracking changes in SARS-CoV-2 Spike: evidence that D614G increases infectivity of the COVID-19 virus (edit) |
10.1016/J.CELL.2020.06.043 |
| 2020-07-02 |
6-Thioguanine blocks SARS-CoV-2 replication by inhibition of PLpro protease activities (edit) |
10.1101/2020.07.01.183020 |
| 2020-07-01 |
The 1.5 A Crystal Structure of the Co-factor Complex of NSP7 and the C-terminal Domain of NSP8 from SARS CoV-2 (edit) |
10.2210/PDB6XIP/PDB |
| 2020-06-30 |
Glycans on the SARS-CoV-2 Spike Control the Receptor Binding Domain Conformation (edit) |
10.1101/2020.06.26.173765 |
| 2020-06-30 |
Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM (edit) |
10.1101/2020.06.30.177097 |
| 2020-06-29 |
Phosphorylation modulates liquid-liquid phase separation of the SARS-CoV-2 N protein (edit) |
10.1101/2020.06.28.176248 |
| 2020-06-29 |
A sequence alignment and analysis of SARS-CoV-2 spike glycoprotein (edit) |
|
| 2020-06-29 |
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damage and constitutes an antiviral target (edit) |
10.1101/2020.06.27.174953 |
| 2020-06-29 |
Proteins Nsp12 and 13 of SARS-CoV-2 Have Mitochondrial Recognition Signal: A Connection with Cellular Mitochondrial Dysfunction and Disease Manifestation (edit) |
10.20944/PREPRINTS202006.0352.V1 |
| 2020-06-28 |
The Global Phosphorylation Landscape of SARS-CoV-2 Infection (edit) |
10.1016/J.CELL.2020.06.034 |
| 2020-06-27 |
Structures, conformations and distributions of SARS-CoV-2 spike protein trimers on intact virions (edit) |
10.1101/2020.06.27.174979 |
| 2020-06-26 |
Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2 (edit) |
10.1101/2020.06.26.173872 |
| 2020-06-26 |
In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges (edit) |
10.1101/2020.06.26.173476 |
| 2020-06-24 |
Molecular Basis for ADP-ribose Binding to the Mac1 Domain of SARS-CoV-2 Nsp3 (edit) |
10.1021/ACS.BIOCHEM.0C00309 |
| 2020-06-24 |
Structural plasticity of SARS-CoV-2 3CL Mpro active site cavity revealed by room temperature X-ray crystallography (edit) |
10.1038/S41467-020-16954-7 |
| 2020-06-24 |
Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 By Disrupting The Spike-ACE2 interaction (edit) |
10.1101/2020.06.24.169334 |
| 2020-06-24 |
SARS-CoV-2 and SARS-CoV: Virtual Screening of Potential inhibitors targeting RNA-dependent RNA polymerase activity (NSP12) (edit) |
10.1002/JMV.26222 |
| 2020-06-23 |
Targeting SARS-COV-2 non-structural protein 16: a virtual drug repurposing study (edit) |
10.1080/07391102.2020.1779133 |
| 2020-06-23 |
The ORF6, ORF8 and nucleocapsid proteins of SARS-CoV-2 inhibit type I interferon signaling pathway (edit) |
10.1016/J.VIRUSRES.2020.198074 |
| 2020-06-23 |
CD209L/L-SIGN and CD209/DC-SIGN act as receptors for SARS-CoV-2 and are differentially expressed in lung and kidney epithelial and endothelial cells (edit) |
10.1101/2020.06.22.165803 |
| 2020-06-23 |
SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography (edit) |
10.1101/2020.06.23.167064 |
| 2020-06-23 |
Biochemical evidence of furin specificity and potential for phospho-regulation at Spike protein S1/S2 cleavage site in SARS-CoV2 but not in SARS-CoV1 or MERS-CoV (edit) |
10.1101/2020.06.23.166900 |
| 2020-06-23 |
Identification of multiple large deletions in ORF7a resulting in in-frame gene fusions in clinical SARS-CoV-2 isolates (edit) |
10.1016/J.JCV.2020.104523 |
| 2020-06-22 |
Structure-based virtual screening and molecular dynamics simulation of SARS-CoV-2 Guanine-N7 methyltransferase (nsp14) for identifying antiviral inhibitors against COVID-19 (edit) |
10.1080/07391102.2020.1778535 |
| 2020-06-20 |
SARS-CoV-2 E protein is a potential ion channel that can be inhibited by Gliclazide and Memantine (edit) |
10.1016/J.BBRC.2020.05.206 |
| 2020-06-19 |
Mechanism and inhibition of SARS-CoV-2 PLpro (edit) |
10.1101/2020.06.18.160614 |
| 2020-06-19 |
Nucleocapsid protein of SARS-CoV-2 phase separates into RNA-rich polymerase-containing condensates (edit) |
10.1101/2020.06.18.160648 |
| 2020-06-18 |
Identification of bioactive compounds from Glycyrrhiza glabra as possible inhibitor of SARS-CoV-2 spike glycoprotein and non-structural protein-15: a pharmacoinformatics study (edit) |
10.1080/07391102.2020.1779132 |
| 2020-06-18 |
The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA (edit) |
10.1101/2020.06.17.158121 |
| 2020-06-18 |
The ORF3a protein of SARS-CoV-2 induces apoptosis in cells (edit) |
10.1038/S41423-020-0485-9 |
| 2020-06-18 |
Cryo-EM structure of the SARS-CoV-2 3a ion channel in lipid nanodiscs (edit) |
10.1101/2020.06.17.156554 |
| 2020-06-18 |
Unexpected free fatty acid binding pocket in the cryo-EM structure of SARS-CoV-2 spike protein (edit) |
10.1101/2020.06.18.158584 |
| 2020-06-17 |
Crystal structure of 2019-nCoV nsp16-nsp10 complex (edit) |
10.2210/PDB7BQ7/PDB |
| 2020-06-17 |
Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis (edit) |
10.1101/2020.06.14.150607 |
| 2020-06-17 |
A thermostable, closed, SARS-CoV-2 spike protein trimer (edit) |
10.1101/2020.06.15.152835 |
| 2020-06-17 |
X-ray Crystallographic Structure of Orf9b from SARS-CoV-2 (edit) |
10.2210/PDB6Z4U/PDB |
| 2020-06-16 |
Proteasome activator PA28γ-dependent degradation of coronavirus disease (COVID-19) nucleocapsid protein (edit) |
10.1016/J.BBRC.2020.06.058 |
| 2020-06-15 |
A Putative Role of de-Mono-ADP-Ribosylation of STAT1 by the SARS-CoV-2 Nsp3 Protein in the Cytokine Storm Syndrome of COVID-19 (edit) |
10.3390/V12060646 |
| 2020-06-12 |
SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists (edit) |
10.1080/22221751.2020.1780953 |
| 2020-06-12 |
Specific viral RNA drives the SARS CoV-2 nucleocapsid to phase separate (edit) |
10.1101/2020.06.11.147199 |
| 2020-06-12 |
The role of furin cleavage site in SARS-CoV-2 spike protein-mediated membrane fusion in the presence or absence of trypsin (edit) |
10.1038/S41392-020-0184-0 |
| 2020-06-12 |
The D614G mutation in the SARS-CoV-2 spike protein reduces S1 shedding and increases infectivity (edit) |
10.1101/2020.06.12.148726 |
| 2020-06-11 |
Shielding and Beyond: The Roles of Glycans in SARS-CoV-2 Spike Protein (edit) |
10.1101/2020.06.11.146522 |
| 2020-06-11 |
Structural analysis of the putative SARS-CoV-2 primase complex (edit) |
10.1016/J.JSB.2020.107548 |
| 2020-06-10 |
SARS-CoV-2 nucleocapsid protein undergoes liquid-liquid phase separation stimulated by RNA and partitions into phases of human ribonucleoproteins (edit) |
10.1101/2020.06.09.141101 |
| 2020-06-10 |
Identification of 22 N-glycosites on spike glycoprotein of SARS-CoV-2 and accessible surface glycopeptide motifs: implications for vaccination and antibody therapeutics (edit) |
10.1093/GLYCOB/CWAA052 |
| 2020-06-10 |
The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S Protein-Mediated Fusion in a Cell Fusion Assay System and Viral Infection In Vitro in a Cell-Type-Dependent Manner (edit) |
10.3390/V12060629 |
| 2020-06-10 |
A Rare Deletion in SARS-CoV-2 ORF6 Dramatically Alters the Predicted Three-Dimensional Structure of the Resultant Protein (edit) |
10.1101/2020.06.09.134460 |
| 2020-06-09 |
Crystal Structure of the SARS-CoV-2 Non-structural Protein 9, Nsp9 (edit) |
10.1016/J.ISCI.2020.101258 |
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Antibody signature induced by SARS-CoV-2 spike protein immunogens in rabbits (edit) |
10.1126/SCITRANSLMED.ABC3539 |
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Neuropilin-1 facilitates SARS-CoV-2 cell entry and provides a possible pathway into the central nervous system (edit) |
10.1101/2020.06.07.137802 |
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SARS-CoV-2 proteases cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species and the search for reservoir hosts (edit) |
10.1101/2020.06.05.135699 |
| 2020-06-05 |
Neuropilin-1 is a host factor for SARS-CoV-2 infection (edit) |
10.1101/2020.06.05.134114 |
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Immune evasion via SARS-CoV-2 ORF8 protein? (edit) |
10.1038/S41577-020-0360-Z |
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Identification of nsp1 gene as the target of SARS-CoV-2 real-time RT-PCR using nanopore whole genome sequencing (edit) |
10.1002/JMV.26140 |
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SARS-Coronavirus-2 Nsp13 Possesses NTPase and RNA Helicase Activities That Can Be Inhibited by Bismuth Salts (edit) |
10.1007/S12250-020-00242-1 |
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Virtual screening, ADME/T, and binding free energy analysis of anti-viral, anti-protease, and anti-infectious compounds against NSP10/NSP16 methyltransferase and main protease of SARS CoV-2 (edit) |
10.1080/10799893.2020.1772298 |
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The pivotal link between ACE2 deficiency and SARS-CoV-2 infection (edit) |
10.1016/J.EJIM.2020.04.037 |
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Comparing the Binding Interactions in the Receptor Binding Domains of SARS-CoV-2 and SARS-CoV (edit) |
10.1021/ACS.JPCLETT.0C01064 |
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Discovery of G-quadruplex-forming sequences in SARS-CoV-2 (edit) |
10.1093/BIB/BBAA114 |
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Structural and Biochemical Characterization of the nsp12-nsp7-nsp8 Core Polymerase Complex from SARS-CoV-2 (edit) |
10.1016/J.CELREP.2020.107774 |
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Evaluation of RdRp & ORF-1b-nsp14-based real-time RT-PCR assays for confirmation of SARS-CoV-2 infection: An observational study (edit) |
10.4103/IJMR.IJMR_1256_20 |
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Optimized pseudotyping conditions for the SARS-COV2 Spike glycoprotein (edit) |
10.1101/2020.05.28.122671 |
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Proteolytic Cleavage of the SARS-CoV-2 Spike Protein and the Role of the Novel S1/S2 Site (edit) |
10.1016/J.ISCI.2020.101212 |
| 2020-05-26 |
SARS-CoV-2 strategically mimics proteolytic activation of human ENaC (edit) |
10.7554/ELIFE.58603 |
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A human neutralizing antibody targets the receptor binding site of SARS-CoV-2 (edit) |
10.1038/S41586-020-2381-Y |
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The ORF8 Protein of SARS-CoV-2 Mediates Immune Evasion through Potently Downregulating MHC-I (edit) |
10.1101/2020.05.24.111823 |
| 2020-05-22 |
Chemistry and Biology of SARS-CoV-2 (edit) |
10.1016/J.CHEMPR.2020.04.023 |
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Structural basis for RNA replication by the SARS-CoV-2 polymerase (edit) |
10.1016/J.CELL.2020.05.034 |
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Structure of replicating SARS-CoV-2 polymerase (edit) |
10.1038/S41586-020-2368-8 |
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Trimeric SARS-CoV-2 Spike interacts with dimeric ACE2 with limited intra-Spike avidity (edit) |
10.1101/2020.05.21.109157 |
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SARS-CoV-2 Nsp9 RNA-replicase (edit) |
10.2210/PDB6WXD/PDB |
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Characterization and noncovalent inhibition of the deubiquitinase and deISGylase activity of SARS-CoV-2 papain-like protease (edit) |
10.1021/ACSINFECDIS.0C00168 |
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Controlling the SARS-CoV-2 Spike Glycoprotein Conformation (edit) |
10.1101/2020.05.18.102087 |
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Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2 (edit) |
10.1101/2020.05.18.102467 |
| 2020-05-18 |
Ebselen as a highly active inhibitor of PLProCoV2 (edit) |
10.1101/2020.05.17.100768 |
| 2020-05-18 |
Potent neutralizing antibodies against SARS-CoV-2 identified by high-throughput single-cell sequencing of convalescent patients' B cells (edit) |
10.1016/J.CELL.2020.05.025 |
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Architecture and self-assembly of the SARS-CoV-2 nucleocapsid protein (edit) |
10.1101/2020.05.17.100685 |
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Distinct conformational states of SARS-CoV-2 spike protein (edit) |
10.1101/2020.05.16.099317 |
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Crystal structures of SARS-CoV-2 ADP-ribose phosphatase (ADRP): from the apo form to ligand complexes (edit) |
10.1101/2020.05.14.096081 |
| 2020-05-14 |
Highly Conserved Homotrimer Cavity Formed by the SARS-CoV-2 Spike Glycoprotein: A Novel Binding Site (edit) |
10.3390/JCM9051473 |
| 2020-05-13 |
Crystal Structure of Nsp16-Nsp10 Heterodimer from SARS-CoV-2 with 7-methyl-GpppA and S-adenosyl-L-homocysteine in the Active Site and Sulfates in the mRNA Binding Groove (edit) |
10.2210/PDB6WRZ/PDB |
| 2020-05-13 |
Crystal Structure of the Second Form of the Co-factor Complex of NSP7 and the C-terminal Domain of NSP8 from SARS CoV-2 (edit) |
10.2210/PDB6WTC/PDB |
| 2020-05-12 |
SARS-CoV-2 ORF3b is a potent interferon antagonist whose activity is further increased by a naturally occurring elongation variant (edit) |
10.1101/2020.05.11.088179 |
| 2020-05-11 |
SARS-CoV-2 spike protein binds heparan sulfate in a length- and sequence-dependent manner (edit) |
10.1101/2020.05.10.087288 |
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Human Intestinal Defensin 5 Inhibits SARS-CoV-2 Invasion by Cloaking ACE2 (edit) |
10.1053/J.GASTRO.2020.05.015 |
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Structure of SARS-CoV-2 nsp16/nsp10 ternary complex (edit) |
10.2210/PDB6WKS/PDB |
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The anti-HIV Drug Nelfinavir Mesylate (Viracept) is a Potent Inhibitor of Cell Fusion Caused by the SARS-CoV-2 Spike (S) Glycoprotein Warranting further Evaluation as an Antiviral against COVID-19 infections (edit) |
10.1002/JMV.25985 |
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Cell entry mechanisms of SARS-CoV-2 (edit) |
10.1073/PNAS.2003138117 |
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The 1.95 A Crystal Structure of the Co-factor Complex of NSP7 and the C-terminal Domain of NSP8 from SARS-CoV-2 (edit) |
10.2210/PDB6WQD/PDB |
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Proteolytic Cleavage of the SARS-CoV-2 Spike Protein and the Role of the Novel S1/S2 Site (edit) |
10.2139/SSRN.3581359 |
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SARS-CoV-2 and ORF3a: Nonsynonymous Mutations, Functional Domains, and Viral Pathogenesis (edit) |
10.1128/MSYSTEMS.00266-20 |
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Nsp7 and Spike Glycoprotein of SARS-CoV-2 Are Envisaged as Potential Targets of Vitamin D and Ivermectin (edit) |
10.20944/PREPRINTS202005.0084.V1 |
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Deducing the N- and O- glycosylation profile of the spike protein of novel coronavirus SARS-CoV-2 (edit) |
10.1093/GLYCOB/CWAA042 |
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Site-specific glycan analysis of the SARS-CoV-2 spike (edit) |
10.1126/SCIENCE.ABB9983 |
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Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir (edit) |
10.1126/SCIENCE.ABC1560 |
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A SARS-CoV-2 protein interaction map reveals targets for drug repurposing (edit) |
10.1038/S41586-020-2286-9 |
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Biochemical characterization of SARS-CoV-2 nucleocapsid protein (edit) |
10.1016/J.BBRC.2020.04.136 |
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SARS-CoV-2 Spike S1 Receptor Binding Domain undergoes Conformational Change upon Interaction with Low Molecular Weight Heparins (edit) |
10.1101/2020.04.29.068486 |
| 2020-04-30 |
Glycosaminoglycans induce conformational change in the SARS-CoV-2 Spike S1 Receptor Binding Domain (edit) |
10.1101/2020.04.29.068767 |
| 2020-04-29 |
An in-silico evaluation of different Saikosaponins for their potency against SARS-CoV-2 using NSP15 and fusion spike glycoprotein as targets (edit) |
10.1080/07391102.2020.1762741 |
| 2020-04-29 |
High-resolution structure of the SARS-CoV-2 NSP3 Macro X domain (edit) |
10.2210/PDB6WEY/PDB |
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STRUCTURE OF THE SARS-CoV-2 ORF7A ENCODED ACCESSORY PROTEIN (edit) |
10.2210/PDB6W37/PDB |
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A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells (edit) |
10.1016/J.MOLCEL.2020.04.022 |
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Structural elucidation of SARS-CoV-2 vital proteins: Computational methods reveal potential drug candidates against main protease, Nsp12 polymerase and Nsp13 helicase (edit) |
10.1016/J.JPHA.2020.04.008 |
| 2020-04-27 |
Structural Basis of RNA Cap Modification by SARS-CoV-2 Coronavirus (edit) |
10.1101/2020.04.26.061705 |
| 2020-04-25 |
Validation of a SARS-CoV-2 spike protein ELISA for use in contact investigations and sero-surveillance (edit) |
10.1101/2020.04.24.057323 |
| 2020-04-22 |
Crystal structure of the co-factor complex of NSP7 and the C-terminal domain of NSP8 from SARS CoV-2 (edit) |
10.2210/PDB6WIQ/PDB |
| 2020-04-20 |
The crystal structure of nsp10-nsp16 heterodimer from SARS-CoV-2 in complex with S-adenosylmethionine (edit) |
10.1101/2020.04.17.047498 |
| 2020-04-17 |
Crystal structure of Nsp15 endoribonuclease NendoU from SARS-CoV-2 (edit) |
10.1002/PRO.3873 |
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Discovery of baicalin and baicalein as novel, natural product inhibitors of SARS-CoV-2 3CL protease in vitro (edit) |
10.1101/2020.04.13.038687 |
| 2020-04-11 |
On the interactions of the receptor-binding domain of SARS-CoV-1 and SARS-CoV-2 spike proteins with monoclonal antibodies and the receptor ACE2 (edit) |
10.1101/2020.04.05.026377 |
| 2020-04-10 |
SARS-CoV-2-encoded nucleocapsid protein acts as a viral suppressor of RNA interference in cells (edit) |
10.1007/S11427-020-1692-1 |
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Evolutionary analysis of SARS-CoV-2: how mutation of Non-Structural Protein 6 (NSP6) could affect viral autophagy (edit) |
10.1016/J.JINF.2020.03.058 |
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Structure of the RNA-dependent RNA polymerase from COVID-19 virus (edit) |
10.1126/SCIENCE.ABB7498 |
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Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites (edit) |
10.1016/J.ANTIVIRAL.2020.104793 |
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Structure of Mpro from COVID-19 virus and discovery of its inhibitors (edit) |
10.1038/S41586-020-2223-Y |
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Development of a Novel, Genome Subtraction-Derived, SARS-CoV-2-Specific COVID-19-nsp2 Real-Time RT-PCR Assay and Its Evaluation Using Clinical Specimens (edit) |
10.3390/IJMS21072574 |
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Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein (edit) |
10.1101/2020.04.02.022194 |
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Molecular Basis for ADP-ribose Binding to the Macro-X Domain of SARS-CoV-2 Nsp3 (edit) |
10.1101/2020.03.31.014639 |
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The crystal structure of papain-like protease of SARS CoV-2 (edit) |
10.2210/PDB6W9C/PDB |
| 2020-03-31 |
Crystal structure of the SARS-CoV-2 non-structural protein 9, Nsp9 (edit) |
10.1101/2020.03.28.013920 |
| 2020-03-30 |
Structural basis of receptor recognition by SARS-CoV-2 (edit) |
10.1038/S41586-020-2179-Y |
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Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor (edit) |
10.1038/S41586-020-2180-5 |
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Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion (edit) |
10.1038/S41422-020-0305-X |
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Site-specific N-glycosylation Characterization of Recombinant SARS-CoV-2 Spike Proteins (edit) |
10.1101/2020.03.28.013276 |
| 2020-03-29 |
The Nucleocapsid Protein of SARS-CoV-2 Abolished Pluripotency in Human Induced Pluripotent Stem Cells (edit) |
10.1101/2020.03.26.010694 |
| 2020-03-28 |
Molecular characterization of SARS-CoV-2 in the first COVID-19 cluster in France reveals an amino acid deletion in nsp2 (Asp268del) (edit) |
10.1016/J.CMI.2020.03.020 |
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Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV (edit) |
10.1038/S41467-020-15562-9 |
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Crystal Structure of the methyltransferase-stimulatory factor complex of NSP16 and NSP10 from SARS CoV-2 (edit) |
10.2210/PDB6W61/PDB |
| 2020-03-22 |
Molecular characterization of SARS-CoV-2 in the first COVID-19 cluster in France reveals an amino-acid deletion in nsp2 (Asp268Del) (edit) |
10.1101/2020.03.19.998179 |
| 2020-03-20 |
The first-in-class peptide binder to the SARS-CoV-2 spike protein (edit) |
10.1101/2020.03.19.999318 |
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Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors (edit) |
10.1126/SCIENCE.ABB3405 |
| 2020-03-18 |
1.80 Angstrom Resolution Crystal Structure of NSP16 - NSP10 Complex from SARS-CoV-2 (edit) |
10.2210/PDB6W4H/PDB |
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Crystal structure of SARS-CoV-2 nucleocapsid protein N-terminal RNA binding domain (edit) |
10.2210/PDB6M3M/PDB |
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Crystal structure of SARS-CoV-2 spike receptor-binding domain bound with ACE2 (edit) |
10.2210/PDB6M0J/PDB |
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The crystal structure of Nsp9 RNA binding protein of SARS CoV-2 (edit) |
10.2210/PDB6W4B/PDB |
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Structure of RNA-dependent RNA polymerase from 2019-nCoV, a major antiviral drug target (edit) |
10.1101/2020.03.16.993386 |
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SARS-CoV-2 invades host cells via a novel route: CD147-spike protein (edit) |
10.1101/2020.03.14.988345 |
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The inhaled corticosteroid ciclesonide blocks coronavirus RNA replication by targeting viral NSP15 (edit) |
10.1101/2020.03.11.987016 |
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Crystal Structure of ADP ribose phosphatase of NSP3 from SARS CoV-2 in the complex with ADP ribose (edit) |
10.2210/PDB6W02/PDB |
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The crystal structure of COVID-19 main protease in apo form (edit) |
10.2210/PDB6M03/PDB |
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COVID-19 main protease with unliganded active site (2019-nCoV, coronavirus disease 2019, SARS-CoV-2) (edit) |
10.2210/PDB6Y84/PDB |
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PanDDA analysis group deposition -- Crystal Structure of COVID-19 main protease in complex with Z1367324110 (edit) |
10.2210/PDB5R81/PDB |
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PanDDA analysis group deposition -- Crystal Structure of COVID-19 main protease in complex with Z219104216 (edit) |
10.2210/PDB5R82/PDB |
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PanDDA analysis group deposition -- Crystal Structure of COVID-19 main protease in complex with Z44592329 (edit) |
10.2210/PDB5R83/PDB |
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Whole Genome Sequence Analysis and Homology Modelling of a 3C Like Peptidase and a Non-Structural Protein 3 of the SARS-CoV-2 Shows Protein Ligand Interaction with an Aza-Peptide and a Noncovalent Lead Inhibitor with Possible Antiviral Properties (edit) |
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Substrate specificity profiling of SARS-CoV-2 Mpro protease provides basis for anti-COVID-19 drug design (edit) |
10.1101/2020.03.07.981928 |
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Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein (edit) |
10.1016/J.CELL.2020.02.058 |
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Crystal Structure of ADP ribose phosphatase of NSP3 from SARS CoV-2 (edit) |
10.2210/PDB6VXS/PDB |
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Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2 (edit) |
10.1126/SCIENCE.ABB2762 |
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SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor (edit) |
10.1016/J.CELL.2020.02.052 |
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Crystal structure of the free enzyme of the SARS-CoV-2 (2019-nCoV) main protease (edit) |
10.2210/PDB6Y2E/PDB |
| 2020-03-04 |
Crystal structure (monoclinic form) of the complex resulting from the reaction between SARS-CoV-2 (2019-nCoV) main protease and tert-butyl (1-((S)-1-(((S)-4-(benzylamino)-3,4-dioxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2-yl)amino)-3-cyclopropyl-1-oxoprop (edit) |
10.2210/PDB6Y2F/PDB |
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Crystal structure of Nsp15 endoribonuclease NendoU from SARS-CoV-2 (edit) |
10.1101/2020.03.02.968388 |
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Potential Inhibitors Targeting RNA-Dependent RNA Polymerase Activity (NSP12) of SARS-CoV-2 (edit) |
10.20944/PREPRINTS202003.0024.V1 |
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Anti-HCV, nucleotide inhibitors, repurposing against COVID-19 (edit) |
10.1016/J.LFS.2020.117477 |
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Structure of Mpro from COVID-19 virus and discovery of its inhibitors (edit) |
10.1101/2020.02.26.964882 |
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COVID-2019: The role of the nsp2 and nsp3 in its pathogenesis (edit) |
10.1002/JMV.25719 |
| 2020-02-20 |
Structure, function and antigenicity of the SARS-CoV-2 spike glycoprotein (edit) |
10.1101/2020.02.19.956581 |
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Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation (edit) |
10.1126/SCIENCE.ABB2507 |
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Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody (edit) |
10.1080/22221751.2020.1729069 |
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Cryo-EM Structure of the 2019-nCoV Spike in the Prefusion Conformation (edit) |
10.1101/2020.02.11.944462 |
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The insert sequence in SARS-CoV-2 enhances spike protein cleavage by TMPRSS (edit) |
10.1101/2020.02.08.926006 |
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Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein (edit) |
10.1038/S41423-020-0374-2 |
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The crystal structure of COVID-19 main protease in complex with an inhibitor N3 (edit) |
10.2210/PDB6LU7/PDB |
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Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag (edit) |
10.1101/2020.01.30.927871 |
| 2020-01-22 |
Homologous recombination within the spike glycoprotein of the newly identified coronavirus may boost cross‐species transmission from snake to human (edit) |
10.1002/JMV.25682 |
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Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties (edit) |
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The Nucleocapsid Protein of SARS-CoV-2 Abolished Pluripotency in Human Induced Pluripotent Stem Cells (edit) |
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3-Hydroxyphthalic Anhydride-Modified Chicken Ovalbumin as a Potential Candidate Inhibits SARS-CoV-2 Infection by Disrupting the Interaction of Spike Protein With Host ACE2 Receptor (edit) |
10.3389/FPHAR.2020.603830 |
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Structural Insight Reveals SARS-CoV-2 Orf7a as an Immunomodulating Factor for Human CD14+ Monocytes (edit) |
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Accelerated induction of apoptosis in insect cells by baculovirus-expressed SARS-CoV membrane protein (edit) |
10.1016/J.FEBSLET.2006.06.003 |
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Crystal Structure of NSP15 Endoribonuclease from SARS CoV-2 (edit) |
10.2210/PDB6VWW/PDB |
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SARS-CoV-2 infects cells after viral entry via clathrin-mediated endocytosis (edit) |
10.1016/J.JBC.2021.100306 |
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