SARS-CoV-2-Queries

litSARSCoV2Proteins.rq

Code examples: curl

SPARQL

SELECT (MAX(?dates) as ?date) ?work ?workLabel ?doi WHERE {
  ?protein wdt:P703 wd:Q82069695 ; wdt:P31 wd:Q8054 .
  ?work wdt:P921 ?protein .
  OPTIONAL { ?work wdt:P577 ?dates . }
  OPTIONAL { ?work wdt:P356 ?doi . }
  SERVICE wikibase:label { bd:serviceParam wikibase:language "en,en". }
} GROUP BY ?work ?workLabel ?doi ORDER BY DESC(?date)

run or edit

Output

date work doi
2022-12-01 ABO blood group is involved in the quality of the specific immune response anti-SARS-CoV-2 (edit) 10.1080/21505594.2021.2019959
2022-12-01 Computational investigation of potent inhibitors against SARS-CoV-2 2′-O-methyltransferase (nsp16): Structure-based pharmacophore modeling, molecular docking, molecular dynamics simulations and binding free energy calculations (edit) 10.1016/J.JMGM.2022.108306
2022-09-01 Frequent occurrence of mutations in nsp3 and nsp4 of SARS-CoV-2, presumably caused by the inhaled asthma drug ciclesonide (edit) 10.1093/PNASNEXUS/PGAC197
2022-08-18 In silico identification of novel SARS-CoV-2 main protease and non-structural protein 13 (nsp13) inhibitors through consensus docking and free binding energy calculations. (edit) 10.2174/1386207325666220818141112
2022-05-27 The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature (edit) 10.1126/SCIADV.ABO5083
2022-05-26 Parsing the role of NSP1 in SARS-CoV-2 infection (edit)
2022-05-20 Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity (edit) 10.1016/J.STR.2022.04.014
2022-05-12 The role of NSP6 in the biogenesis of the SARS-CoV-2 replication organelle (edit) 10.1038/S41586-022-04835-6
2022-05-11 SARS-CoV-2 Variants of Concern Hijack IFITM2 for Efficient Replication in Human Lung Cells (edit) 10.1128/JVI.00594-22
2022-05-09 A glucose-like metabolite deficient in diabetes inhibits cellular entry of SARS-CoV-2 (edit) 10.1038/S42255-022-00567-Z
2022-05-08 ADAM10 and ADAM17 promote SARS‐CoV‐2 cell entry and spike protein‐mediated lung cell fusion (edit) 10.15252/EMBR.202154305
2022-05-01 Recognition and Cleavage of Human tRNA Methyltransferase TRMT1 by the SARS‐CoV‐2 Main Protease (edit) 10.1096/FASEBJ.2022.36.S1.R4632
2022-05-01 The Effect of Glycosylation Modulators on the Trafficking and Interaction of Spike Protein S1 Subunit and Angiotensin‐Converting Enzyme 2 (edit) 10.1096/FASEBJ.2022.36.S1.R3340
2022-05-01 Going viral in the islet: mediators of SARS-CoV-2 entry beyond ACE2 (edit) 10.1530/JME-21-0282
2022-05-01 Variation in ORF3a Protein of SARS‐CoV‐2 Decreases The Severity of Host Cell Damage (edit) 10.1096/FASEBJ.2022.36.S1.R4149
2022-05-01 Synthesis of the transmembrane domain of the accessory protein ORF7a of SARS‐CoV‐2 using solid phase peptide synthesis and analyzing the oligomerization state (edit) 10.1096/FASEBJ.2022.36.S1.R3870
2022-04-25 Histamine Potentiates SARS-CoV-2 Spike Protein Entry Into Endothelial Cells (edit) 10.3389/FPHAR.2022.872736
2022-04-19 Potent Inhibition of SARS-CoV-2 nsp14 N7-Methyltransferase by Sulfonamide-Based Bisubstrate Analogues (edit) 10.1021/ACS.JMEDCHEM.2C00120
2022-04-17 Clinically observed deletions in SARS-CoV-2 Nsp1 affect its stability and ability to inhibit translation (edit) 10.1002/1873-3468.14354
2022-04-12 SARS-CoV-2 spike protein–induced cell fusion activates the cGAS-STING pathway and the interferon response (edit) 10.1126/SCISIGNAL.ABG8744
2022-04-07 SARS-CoV-2 nsp5 Exhibits Stronger Catalytic Activity and Interferon Antagonism than Its SARS-CoV Ortholog (edit) 10.1128/JVI.00037-22
2022-04-05 Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2 (edit) 10.1073/PNAS.2117142119
2022-04-05 Online Hydrophilic Interaction Chromatography (HILIC) Enhanced Top-Down Mass Spectrometry Characterization of the SARS-CoV-2 Spike Receptor-Binding Domain (edit) 10.1021/ACS.ANALCHEM.2C00139
2022-04-05 pH- and Calcium-Dependent Aromatic Network in the SARS-CoV-2 Envelope Protein (edit) 10.1021/JACS.2C00973
2022-03-29 Intranasal administration of a single dose of a candidate live attenuated vaccine derived from an NSP16-deficient SARS-CoV-2 strain confers sterilizing immunity in animals (edit) 10.1038/S41423-022-00855-4
2022-03-28 SARS-CoV-2 pseudovirus enters the host cells through spike protein-CD147 in Arf6-dependent manner (edit) 10.1080/22221751.2022.2059403
2022-03-28 Distinctive Roles of Furin and TMPRSS2 in SARS-CoV-2 Infectivity (edit) 10.1128/JVI.00128-22
2022-03-28 Viral Mimicry of Interleukin-17A by SARS-CoV-2 ORF8 (edit) 10.1128/MBIO.00402-22
2022-03-22 SARS-CoV-2 NSP13 helicase suppresses interferon signaling by perturbing JAK1 phosphorylation of STAT1 (edit) 10.1186/S13578-022-00770-1
2022-03-22 In Silico Insights towards the Identification of SARS-CoV-2 NSP13 Helicase Druggable Pockets (edit) 10.3390/BIOM12040482
2022-03-17 The SARS-CoV-2 Entry Inhibition Mechanisms of Serine Protease Inhibitors, OM-85, Heparin and Soluble HS Might Be Linked to HS Attachment Sites (edit) 10.3390/MOLECULES27061947
2022-03-16 Free ISG15 and protein ISGylation emerging in SARS-CoV-2 infection (edit) 10.2174/1389450123666220316094720
2022-03-16 Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry (edit) 10.7554/ELIFE.77444
2022-03-16 SARS-CoV-2: Receptor and Co-receptor Tropism Probability (edit) 10.1007/S00284-022-02807-7
2022-03-16 SARS-CoV-2 Nsp14 mediates the effects of viral infection on the host cell transcriptome (edit) 10.7554/ELIFE.71945
2022-03-14 When cyclin‐dependent kinases meet viral infections, including SARS‐CoV‐2 (edit) 10.1002/JMV.27719
2022-03-08 An intra-cytoplasmic route for SARS-CoV-2 transmission unveiled by Helium-ion microscopy (edit) 10.1038/S41598-022-07867-0
2022-03-08 Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication–transcription complex (edit) 10.1038/S41594-022-00734-6
2022-03-07 Cytoplasmic domain and enzymatic activity of ACE2 are not required for PI4KB dependent endocytosis entry of SARS-CoV-2 into host cells (edit) 10.1016/J.VIRS.2022.03.003
2022-03-03 SARS-CoV-2 ORF3a induces RETREG1/FAM134B-dependent reticulophagy and triggers sequential ER stress and inflammatory responses during SARS-CoV-2 infection (edit) 10.1080/15548627.2022.2039992
2022-03-01 Modulation of the monomer-dimer equilibrium and catalytic activity of SARS-CoV-2 main protease by a transition-state analog inhibitor (edit) 10.1038/S42003-022-03084-7
2022-03-01 The key features of SARS-CoV-2 leader and NSP1 required for viral escape of NSP1-mediated repression (edit) 10.1261/RNA.079086.121
2022-02-28 Optimizing peptide inhibitors of SARS-Cov-2 nsp10/nsp16 methyltransferase predicted through molecular simulation and machine learning (edit) 10.1016/J.IMU.2022.100886
2022-02-28 SARS-CoV-2 nucleocapsid protein targets a conserved surface groove of the NTF2-like domain of G3BP1 (edit) 10.1016/J.JMB.2022.167516
2022-02-25 A Deadly Embrace: Hemagglutination Mediated by SARS-CoV-2 Spike Protein at Its 22 N-Glycosylation Sites, Red Blood Cell Surface Sialoglycoproteins, and Antibody (edit) 10.3390/IJMS23052558
2022-02-24 Targeting SARS-CoV-2 Proteases and Polymerase for COVID-19 Treatment: State of the Art and Future Opportunities (edit) 10.1021/ACS.JMEDCHEM.0C01140
2022-02-24 Viroporins: structure, function, and their role in the life cycle of SARS-CoV-2 (edit) 10.1016/J.BIOCEL.2022.106185
2022-02-23 Neuropilin‐1‐Mediated SARS‐CoV‐2 Infection in Bone Marrow‐Derived Macrophages Inhibits Osteoclast Differentiation (edit) 10.1002/ADBI.202200007
2022-02-23 Interactions of Severe Acute Respiratory Syndrome Coronavirus 2 Protein E With Cell Junctions and Polarity PSD-95/Dlg/ZO-1-Containing Proteins (edit) 10.3389/FMICB.2022.829094
2022-02-23 The stalk domain of SARS-CoV-2 NSP13 is essential for its helicase activity (edit) 10.1016/J.BBRC.2022.02.068
2022-02-22 The SARS‐CoV‐2 Spike Glycoprotein Directly Binds Exogeneous Sialic Acids: A NMR View (edit) 10.1002/ANIE.202201432
2022-02-22 Identification of a SARS-CoV-2 host metalloproteinase-dependent entry pathway differentially used by SARS-CoV-2 and variants of concern Alpha, Delta, and Omicron (edit) 10.1101/2022.02.19.481107
2022-02-21 Decoupling SARS-CoV-2 ORF6 localization and interferon antagonism (edit) 10.1242/JCS.259666
2022-02-21 SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells (edit) 10.1016/J.CELREP.2022.110503
2022-02-18 Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity (edit) 10.1101/2022.02.17.480845
2022-02-16 Lipid and Nucleocapsid N-Protein Accumulation in COVID-19 Patient Lung and Infected Cells (edit) 10.1128/SPECTRUM.01271-21
2022-02-15 Inhibition of Protein Glycosylation Blocks SARS-CoV-2 Infection (edit) 10.1128/MBIO.03718-21
2022-02-14 Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN (edit) 10.1073/PNAS.2106379119
2022-02-14 Strikingly Different Roles of SARS-CoV-2 Fusion Peptides Uncovered by Neutron Scattering (edit) 10.1021/JACS.1C09856
2022-02-14 Structural polymorphism of coiled‐coils from the stalk domain of SARS‐CoV‐2 spike protein (edit) 10.1096/FJ.202101670R
2022-02-11 SARS-CoV-2 accessory protein ORF8 is secreted extracellularly as a glycoprotein homodimer (edit) 10.1016/J.JBC.2022.101724
2022-02-09 Integrin mediates cell entry of the SARS-CoV-2 virus independent of cellular receptor ACE2 (edit) 10.1016/J.JBC.2022.101710
2022-02-07 Cryo-EM structure of the SARS-CoV-2 Omicron spike (edit) 10.1016/J.CELREP.2022.110428
2022-02-07 The spike protein of SARS-CoV-2 induces endothelial inflammation through integrin α5β1 and NF-κB signaling (edit) 10.1016/J.JBC.2022.101695
2022-02-06 Identification of potential target endoribonuclease NSP15 inhibitors of SARS-COV-2 from natural products through high-throughput virtual screening and molecular dynamics simulation (edit) 10.1111/JFBC.14085
2022-02-01 Molecular Docking Studies to Identify Promising Natural Inhibitors Targeting SARS-CoV-2 Nsp10-Nsp16 Protein Complex (edit) 10.4274/TJPS.GALENOS.2021.56957
2022-02-01 The nsp15 Nuclease as a Good Target to Combat SARS-CoV-2: Mechanism of Action and Its Inactivation with FDA-Approved Drugs (edit) 10.3390/MICROORGANISMS10020342
2022-02-01 Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant (edit) 10.1038/S41586-022-04462-1
2022-02-01 Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts tropism and fusogenicity (edit) 10.1038/S41586-022-04474-X
2022-02-01 The E3 Ubiquitin Ligase RNF5 Facilitates SARS-CoV-2 Membrane Protein-Mediated Virion Release (edit) 10.1128/MBIO.03168-21
2022-02-01 Genome-wide analyses reveal the detrimental impacts of SARS-CoV-2 viral gene Orf9c on human pluripotent stem cell-derived cardiomyocytes (edit) 10.1016/J.STEMCR.2022.01.014
2022-01-29 The function of SARS-CoV-2 spike protein is impaired by disulfide-bond disruption with mutation at cysteine-488 and by thiol-reactive N-acetyl-cysteine and glutathione (edit) 10.1016/J.BBRC.2022.01.106
2022-01-27 Effect of SARS-CoV-2 spike mutations on its activation by TMPRSS2 and TMPRSS13 (edit) 10.1101/2022.01.26.477969
2022-01-26 Trypsin enhances SARS-CoV-2 infection by facilitating viral entry (edit) 10.1007/S00705-021-05343-0
2022-01-25 Extracellular vimentin is an attachment factor that facilitates SARS-CoV-2 entry into human endothelial cells (edit) 10.1073/PNAS.2113874119
2022-01-25 N7-Methylation of the Coronavirus RNA Cap Is Required for Maximal Virulence by Preventing Innate Immune Recognition (edit) 10.1128/MBIO.03662-21
2022-01-24 SARS-CoV-2 NSP5 and N protein counteract the RIG-I signaling pathway by suppressing the formation of stress granules (edit) 10.1038/S41392-022-00878-3
2022-01-22 Insights into the specificity for the interaction of the promiscuous SARS-CoV-2 nucleocapsid protein N-terminal domain with deoxyribonucleic acids (edit) 10.1016/J.IJBIOMAC.2022.01.121
2022-01-21 The intrinsically disordered SARS-CoV-2 nucleoprotein in dynamic complex with its viral partner nsp3a (edit) 10.1126/SCIADV.ABM4034
2022-01-17 Characterization of the SARS-CoV-2 ExoN (nsp14ExoN–nsp10) complex: implications for its role in viral genome stability and inhibitor identification (edit) 10.1093/NAR/GKAB1303
2022-01-14 Detection and discrimination of SARS-CoV-2 spike protein-derived peptides using THz metamaterials (edit) 10.1016/J.BIOS.2022.113981
2022-01-12 Syndecan-4 Is a Key Facilitator of the SARS-CoV-2 Delta Variant's Superior Transmission (edit) 10.3390/IJMS23020796
2022-01-12 SARS-CoV-2 membrane protein causes the mitochondrial apoptosis and pulmonary edema via targeting BOK (edit) 10.1038/S41418-022-00928-X
2022-01-11 Alpha-Soluble NSF Attachment Protein Prevents the Cleavage of the SARS-CoV-2 Spike Protein by Functioning as an Interferon-Upregulated Furin Inhibitor (edit) 10.1128/MBIO.02443-21
2022-01-08 SARS-CoV-2 non-structural protein 6 triggers NLRP3-dependent pyroptosis by targeting ATP6AP1 (edit) 10.1038/S41418-021-00916-7
2022-01-07 SARS-CoV-2 NSP13 Inhibits Type I IFN Production by Degradation of TBK1 via p62-Dependent Selective Autophagy (edit) 10.4049/JIMMUNOL.2100684
2022-01-07 Toward wide-spectrum antivirals against coronaviruses: Molecular characterization of SARS-CoV-2 NSP13 helicase inhibitors (edit) 10.1126/SCIADV.ABJ4526
2022-01-05 UV-4B potently inhibits replication of multiple SARS-CoV-2 strains in clinically relevant human cell lines (edit) 10.31083/J.FBL2701003
2022-01-04 SARS-CoV-2 spike engagement of ACE2 primes S2' site cleavage and fusion initiation (edit) 10.1073/PNAS.2111199119
2022-01-03 The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanism (edit) 10.1101/2022.01.03.21268111
2022-01-01 Identification of fragments binding to SARS-CoV-2 nsp10 reveals ligand-binding sites in conserved interfaces between nsp10 and nsp14/nsp16 (edit) 10.1039/D1CB00135C
2022-01-01 Proteolytic activation of SARS-CoV-2 spike protein (edit) 10.1111/1348-0421.12945
2022-01-01 Glycomimetic ligands block the interaction of SARS-CoV-2 spike protein with C-type lectin co-receptors (edit) 10.1039/D2CC00121G
2022-01-01 D155Y substitution of SARS-CoV-2 ORF3a weakens binding with Caveolin-1 (edit) 10.1016/J.CSBJ.2022.01.017
2022-01-01 Understanding the Role of SARS-CoV-2 ORF3a in Viral Pathogenesis and COVID-19 (edit) 10.3389/FMICB.2022.854567
2021-12-31 Cellular miR-150-5p may have a crucial role to play in the biology of SARS-CoV-2 infection by regulating nsp10 gene (edit) 10.1080/15476286.2021.2010959
2021-12-30 Interactome profiling reveals interaction of SARS-CoV-2 NSP13 with host factor STAT1 to suppress interferon signaling (edit) 10.1093/JMCB/MJAB068
2021-12-27 The interactions of ZDHHC5/GOLGA7 with SARS-CoV-2 spike (S) protein and their effects on S protein's subcellular localization, palmitoylation and pseudovirus entry (edit) 10.1186/S12985-021-01722-W
2021-12-24 SARS-CoV-2 Omicron variant shows less efficient replication and fusion activity when compared with delta variant in TMPRSS2-expressed cells (edit) 10.1080/22221751.2021.2023329
2021-12-24 Modulation of the NLRP3 inflammasome by Sars-CoV-2 Envelope protein (edit) 10.1038/S41598-021-04133-7
2021-12-22 The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147 receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease (edit) 10.1042/CS20210735
2021-12-20 Activation of the SARS-CoV-2 NSP14 3'-5' exoribonuclease by NSP10 and response to antiviral inhibitors (edit) 10.1016/J.JBC.2021.101518
2021-12-17 The binding of heparin to spike glycoprotein inhibits SARS-CoV-2 infection by three mechanisms (edit) 10.1016/J.JBC.2021.101507
2021-12-17 SARS-CoV-2-triggered mast cell rapid degranulation induces alveolar epithelial inflammation and lung injury (edit) 10.1038/S41392-021-00849-0
2021-12-15 Highly conserved s2m element of SARS-CoV-2 dimerizes via a kissing complex and interacts with host miRNA-1307-3p (edit) 10.1093/NAR/GKAB1226
2021-12-15 Metalloproteinase-dependent and TMPRSS2-independnt cell surface entry pathway of SARS-CoV-2 requires the furin-cleavage site and the S2 domain of spike protein (edit) 10.1101/2021.12.14.472513
2021-12-13 Exploring the therapeutic nature of limonoids and triterpenoids against SARS-CoV-2 by targeting nsp13, nsp14, and nsp15 through molecular docking and dynamics simulations (edit) 10.1016/J.JTCME.2021.12.002
2021-12-10 Membrane fusion and immune evasion by the spike protein of SARS-CoV-2 Delta variant (edit) 10.1126/SCIENCE.ABL9463
2021-12-09 SARS-CoV-2 ORF3a Induces Incomplete Autophagy via the Unfolded Protein Response (edit) 10.3390/V13122467
2021-12-07 N-glycosylation profiles of the SARS-CoV-2 spike D614G mutant and its ancestral protein characterized by advanced mass spectrometry (edit) 10.1038/S41598-021-02904-W
2021-12-07 Cell fusion as a link between the SARS-CoV-2 spike protein, COVID-19 complications, and vaccine side effects (edit) 10.18632/ONCOTARGET.28088
2021-12-06 SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-kB pathway (edit) 10.7554/ELIFE.68563
2021-12-06 Forced association of SARS-CoV-2 proteins with the yeast proteome perturb vesicle trafficking (edit) 10.15698/MIC2021.12.766
2021-12-05 Extracellular Vimentin as a Target Against SARS‐CoV‐2 Host Cell Invasion (edit) 10.1002/SMLL.202105640
2021-12-04 SARS-CoV-2 Nucleocapsid protein attenuates stress granules and interacts with mRNAs to impair host stress response (edit) 10.1016/J.ISCI.2021.103562
2021-12-04 A structural view of the SARS-CoV-2 virus and its assembly (edit) 10.1016/J.COVIRO.2021.11.011
2021-12-03 SARS-CoV-2 Nsp5 Protein Causes Acute Lung Inflammation, A Dynamical Mathematical Model (edit) 10.3389/FSYSB.2021.764155
2021-12-01 Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formation (edit) 10.1038/S41467-021-27511-1
2021-12-01 Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate (edit) 10.1080/22221751.2021.1932607
2021-12-01 Pannexin-1 channel opening is critical for COVID-19 pathogenesis (edit) 10.1016/J.ISCI.2021.103478
2021-12-01 SARS-CoV-2 uses metabotropic glutamate receptor subtype 2 as an internalization factor to infect cells (edit) 10.1038/S41421-021-00357-Z
2021-12-01 The spike protein of SARS-CoV-2 virus induces heme oxygenase-1: Pathophysiologic implications (edit) 10.1016/J.BBADIS.2021.166322
2021-12-01 SARS-CoV-2 pseudovirus infectivity and expression of viral entry-related factors ACE2, TMPRSS2, Kim-1, and NRP-1 in human cells from the respiratory, urinary, digestive, reproductive, and immune systems (edit) 10.1002/JMV.27244
2021-12-01 SARS-CoV-2 interaction with Siglec-1 mediates trans-infection by dendritic cells (edit) 10.1038/S41423-021-00794-6
2021-12-01 The short isoform of the host antiviral protein ZAP acts as an inhibitor of SARS-CoV-2 programmed ribosomal frameshifting (edit) 10.1038/S41467-021-27431-0
2021-11-30 Multiplex Gene Tagging with CRISPR-Cas9 for Live-Cell Microscopy and Application to Study the Role of SARS-CoV-2 Proteins in Autophagy, Mitochondrial Dynamics, and Cell Growth (edit) 10.1089/CRISPR.2021.0041
2021-11-29 SARS-CoV-2 ORF10 suppresses the antiviral innate immune response by degrading MAVS through mitophagy (edit) 10.1038/S41423-021-00807-4
2021-11-29 The SARS-CoV-2 RNA polymerase is a viral RNA capping enzyme (edit) 10.1093/NAR/GKAB1160
2021-11-26 Oxidative stress transforms 3CLpro into an insoluble and more active form to promote SARS-CoV-2 replication (edit) 10.1016/J.REDOX.2021.102199
2021-11-26 Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2 (edit) 10.1038/S41422-021-00595-6
2021-11-25 Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation (edit) 10.1038/S41586-021-04266-9
2021-11-24 Glycosylation and disulfide bonding of wild-type SARS-CoV-2 spike glycoprotein (edit) 10.1128/JVI.01626-21
2021-11-23 SARS‐CoV‐2 N Protein Induces Acute Kidney Injury via Smad3‐Dependent G1 Cell Cycle Arrest Mechanism (edit) 10.1002/ADVS.202103248
2021-11-22 TMPRSS2 promotes SARS-CoV-2 evasion from NCOA7-mediated restriction (edit) 10.1371/JOURNAL.PPAT.1009820
2021-11-18 Backbone and Ile, Leu, Val methyl group resonance assignment of CoV-Y domain of SARS-CoV-2 non-structural protein 3 (edit) 10.1007/S12104-021-10059-Y
2021-11-18 Clinical Antiviral Drug Arbidol Inhibits Infection by SARS-CoV-2 and Variants through Direct Binding to the Spike Protein (edit) 10.1021/ACSCHEMBIO.1C00756
2021-11-18 The role of cell surface sialic acids for SARS-CoV-2 infection (edit) 10.1093/GLYCOB/CWAB032
2021-11-15 The glycosylation in SARS-CoV-2 and its receptor ACE2 (edit) 10.1038/S41392-021-00809-8
2021-11-15 Nanometer-resolution in situ structure of the SARS-CoV-2 postfusion spike protein (edit) 10.1073/PNAS.2112703118
2021-11-15 SARS-CoV-2 spike protein removes lipids from model membranes and interferes with the capacity of high density lipoprotein to exchange lipids (edit) 10.1016/J.JCIS.2021.06.056
2021-11-15 SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis (edit) 10.1038/S41467-021-26910-8
2021-11-13 SARS-CoV-2 deregulates the vascular and immune functions of brain pericytes via Spike protein (edit) 10.1016/J.NBD.2021.105561
2021-11-12 Disulfide bonds play a critical role in the structure and function of the receptor-binding domain of the SARS-CoV-2 Spike antigen (edit) 10.1016/J.JMB.2021.167357
2021-11-11 Epigenetic glycosylation of SARS-CoV-2 impact viral infection through DC&L-SIGN receptors (edit) 10.1016/J.ISCI.2021.103426
2021-11-09 Molecular docking and pharmacokinetic studies of phytocompounds from Nigerian Medicinal Plants as promising inhibitory agents against SARS-CoV-2 methyltransferase (nsp16) (edit) 10.1186/S43141-021-00273-5
2021-11-09 Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2 (edit) 10.1038/S41589-021-00924-1
2021-11-05 In-solution buffer-free digestion allows full-sequence coverage and complete characterization of post-translational modifications of the receptor-binding domain of SARS-CoV-2 in a single ESI–MS spectrum (edit) 10.1007/S00216-021-03721-W
2021-11-04 CTD of SARS‐CoV‐2 N protein is a cryptic domain for binding ATP and nucleic acid that interplay in modulating phase separation (edit) 10.1002/PRO.4221
2021-11-03 Furin cleavage of the SARS-CoV-2 spike is modulated by O-glycosylation (edit) 10.1073/PNAS.2109905118
2021-11-03 SARS-CoV-2 Spike Protein S1-Mediated Endothelial Injury and Pro-Inflammatory State Is Amplified by Dihydrotestosterone and Prevented by Mineralocorticoid Antagonism (edit) 10.3390/V13112209
2021-11-01 Membranotropic and biological activities of the membrane fusion peptides from SARS-CoV spike glycoprotein: The importance of the complete internal fusion peptide domain (edit) 10.1016/J.BBAMEM.2021.183697
2021-11-01 Zn‐Induced Interactions Between SARS‐CoV‐2 orf7a and BST2/Tetherin (edit) 10.1002/OPEN.202100217
2021-10-31 Structural basis for the interaction of SARS‐CoV‐2 virulence factor nsp1 with DNA Polymerase a ‐ Primase (edit) 10.1002/PRO.4220
2021-10-29 SARS-CoV-2 spike protein causes blood coagulation and thrombosis by competitive binding to heparan sulfate (edit) 10.1016/J.IJBIOMAC.2021.10.112
2021-10-28 A natural product compound inhibits coronaviral replication in vitro by binding to the conserved Nsp9 SARS-CoV-2 protein (edit) 10.1016/J.JBC.2021.101362
2021-10-27 Structural, Electronic, and Electrostatic Determinants for Inhibitor Binding to Subsites S1 and S2 in SARS-CoV-2 Main Protease (edit) 10.1021/ACS.JMEDCHEM.1C01475
2021-10-26 Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CL substrate degradome (edit) 10.1016/J.CELREP.2021.109892
2021-10-26 SARS-CoV-2 exploits host DGAT and ADRP for efficient replication (edit) 10.1038/S41421-021-00338-2
2021-10-26 Betacoronavirus Assembly: Clues and Perspectives for Elucidating SARS-CoV-2 Particle Formation and Egress (edit) 10.1128/MBIO.02371-21
2021-10-23 SARS-CoV-2 Spike Protein Disrupts Blood-Brain Barrier Integrity via RhoA Activation (edit) 10.1007/S11481-021-10029-0
2021-10-21 The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells (edit) 10.1038/S41593-021-00926-1
2021-10-21 Micronucleus production, activation of DNA damage response and cGAS-STING signaling in syncytia induced by SARS-CoV-2 infection (edit) 10.1186/S13062-021-00305-7
2021-10-18 Altered ISGylation drives aberrant macrophage-dependent immune responses during SARS-CoV-2 infection (edit) 10.1038/S41590-021-01035-8
2021-10-18 SARS-CoV-2 promotes RIPK1 activation to facilitate viral propagation (edit) 10.1038/S41422-021-00578-7
2021-10-14 Integrin activation is an essential component of SARS-CoV-2 infection (edit) 10.1038/S41598-021-99893-7
2021-10-13 The effect of glycosylation of SARS-CoV-2 spike protein on the virus interaction with the host cell ACE2 receptor (edit) 10.1016/J.ISCI.2021.103272
2021-10-13 SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro (edit) 10.3390/V13102056
2021-10-12 B.1.617.2 enters and fuses lung cells with increased efficiency and evades antibodies induced by infection and vaccination (edit) 10.1016/J.CELREP.2021.109825
2021-10-11 SARS-CoV-2 nucleocapsid protein forms condensates with viral genomic RNA (edit) 10.1371/JOURNAL.PBIO.3001425
2021-10-11 ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress (edit) 10.1016/J.DEVCEL.2021.10.006
2021-10-08 SARS-CoV-2 spike protein harnesses SNX27-mediated endocytic recycling pathway (edit) 10.1002/MCO2.92
2021-10-06 Highly efficient SARS-CoV-2 infection of human cardiomyocytes: spike protein-mediated cell fusion and its inhibition (edit) 10.1128/JVI.01368-21
2021-10-05 Mechanisms of SARS-CoV-2 entry into cells (edit) 10.1038/S41580-021-00418-X
2021-10-02 SARS‐CoV‐2 Alpha, Beta and Delta variants display enhanced Spike‐mediated Syncytia Formation (edit) 10.15252/EMBJ.2021108944
2021-10-01 The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation (edit) 10.1371/JOURNAL.PPAT.1009412
2021-10-01 6-Thioguanine blocks SARS-CoV-2 replication by inhibition of PLpro (edit) 10.1016/J.ISCI.2021.103213
2021-10-01 The mechanism and consequences of SARS-CoV-2 spike-mediated fusion and syncytia formation (edit) 10.1016/J.JMB.2021.167280
2021-10-01 S-acylation controls SARS-CoV-2 membrane lipid organization and enhances infectivity (edit) 10.1016/J.DEVCEL.2021.09.016
2021-10-01 O-glycosylation pattern of the SARS-CoV-2 spike protein reveals an "O-Follow-N" rule (edit) 10.1038/S41422-021-00545-2
2021-10-01 An evidence that SARS-Cov-2/COVID-19 spike protein (SP) damages hematopoietic stem/progenitor cells in the mechanism of pyroptosis in Nlrp3 inflammasome-dependent manner (edit) 10.1038/S41375-021-01332-Z
2021-10-01 Proteases and variants: context matters for SARS-CoV-2 entry assays (edit) 10.1016/J.COVIRO.2021.07.004
2021-09-30 Targeting the coronavirus nucleocapsid protein through GSK-3 inhibition (edit) 10.1073/PNAS.2113401118
2021-09-30 The N-terminal domain of SARS-CoV-2 nsp1 plays key roles in suppression of cellular gene expression and preservation of viral gene expression (edit) 10.1016/J.CELREP.2021.109841
2021-09-28 ORF3a Protein of Severe Acute Respiratory Syndrome Coronavirus 2 Inhibits Interferon-Activated Janus Kinase/Signal Transducer and Activator of Transcription Signaling via Elevating Suppressor of Cytokine Signaling 1 (edit) 10.3389/FMICB.2021.752597
2021-09-27 Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U (edit) 10.1093/NAR/GKAB719
2021-09-27 Identifying Distinct Structural Features of the SARS-CoV-2 Spike Protein Fusion Domain Essential for Membrane Interaction (edit) 10.1021/ACS.BIOCHEM.1C00543
2021-09-23 Palmitoylation of SARS‐CoV‐2 S protein is critical for S‐mediated syncytia formation and virus entry (edit) 10.1002/JMV.27339
2021-09-23 SARS-CoV-2 spike protein receptor-binding domain N-glycans facilitate viral internalization in respiratory epithelial cells (edit) 10.1016/J.BBRC.2021.09.053
2021-09-22 Direct activation of endothelial cells by SARS-CoV-2 nucleocapsid protein is blocked by Simvastatin (edit) 10.1128/JVI.01396-21
2021-09-21 Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential (edit) 10.1038/S41467-021-25796-W
2021-09-21 SARS-CoV-2 Nsp5 Demonstrates Two Distinct Mechanisms Targeting RIG-I and MAVS To Evade the Innate Immune Response (edit) 10.1128/MBIO.02335-21
2021-09-20 SARS-CoV-2 S glycoprotein binding to multiple host receptors enables cell entry and infection (edit) 10.1007/S10719-021-10021-Z
2021-09-20 On the weak binding and spectroscopic signature of SARS‐CoV‐2 nsp14 interaction with RNA (edit) 10.1002/CBIC.202100486
2021-09-17 A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses (edit) 10.1038/S41467-021-25729-7
2021-09-16 Assessment of the binding interactions of SARS-CoV-2 spike glycoprotein variants (edit) 10.1016/J.JPHA.2021.09.006
2021-09-15 SARS-CoV-2 nucleocapsid suppresses host pyroptosis by blocking Gasdermin D cleavage (edit) 10.15252/EMBJ.2021108249
2021-09-14 MOV10 Helicase Interacts with Coronavirus Nucleocapsid Protein and Has Antiviral Activity (edit) 10.1128/MBIO.01316-21
2021-09-12 Infection and transmission of SARS‐CoV‐2 depends on heparan sulfate proteoglycans (edit) 10.15252/EMBJ.2020106765
2021-09-09 Sequences in the cytoplasmic tail of SARS-CoV-2 Spike facilitate expression at the cell surface and syncytia formation (edit) 10.1038/S41467-021-25589-1
2021-09-08 Interactome Analysis of the Nucleocapsid Protein of SARS-CoV-2 Virus (edit) 10.3390/PATHOGENS10091155
2021-09-08 A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease (edit) 10.1016/J.CELREP.2021.109754
2021-09-08 Structure of SARS-CoV-2 spike protein (edit) 10.1016/J.COVIRO.2021.08.010
2021-09-06 Deamidation drives molecular aging of the SARS-CoV-2 spike protein receptor-binding motif (edit) 10.1016/J.JBC.2021.101175
2021-09-03 SARS-CoV-2 3C-like protease antagonizes interferon-beta production by facilitating the degradation of IRF3 (edit) 10.1016/J.CYTO.2021.155697
2021-09-01 Manipulation of autophagy by SARS-CoV-2 proteins (edit) 10.1080/15548627.2021.1953847
2021-09-01 A dual-role of SARS-CoV-2 nucleocapsid protein in regulating innate immune response (edit) 10.1038/S41392-021-00742-W
2021-09-01 The SARS-CoV-2 Nsp3 macrodomain reverses PARP9/DTX3L-dependent ADP-ribosylation induced by interferon signaling (edit) 10.1016/J.JBC.2021.101041
2021-09-01 Cellular host factors for SARS-CoV-2 infection (edit) 10.1038/S41564-021-00958-0
2021-08-31 Mechanical activation of spike fosters SARS-CoV-2 viral infection (edit) 10.1038/S41422-021-00558-X
2021-08-31 Impact of temperature on the affinity of SARS-CoV-2 Spike glycoprotein for host ACE2 (edit) 10.1016/J.JBC.2021.101151
2021-08-31 D614G Substitution of SARS-CoV-2 Spike Protein Increases Syncytium Formation and Virus Titer via Enhanced Furin-Mediated Spike Cleavage (edit) 10.1128/MBIO.00587-21
2021-08-31 The nucleotide addition cycle of the SARS-CoV-2 polymerase (edit) 10.1016/J.CELREP.2021.109650
2021-08-30 Substrate Specificity of SARS-CoV-2 Nsp10-Nsp16 Methyltransferase (edit) 10.3390/V13091722
2021-08-28 Discovering potential inhibitors against SARS-CoV-2 by targeting Nsp13 Helicase (edit) 10.1080/07391102.2021.1970024
2021-08-27 Host ADP-ribosylation and the SARS-CoV-2 macrodomain (edit) 10.1042/BST20201212
2021-08-27 SARS-CoV-2 spike promotes inflammation and apoptosis through autophagy by ROS-suppressed PI3K/AKT/mTOR signaling (edit) 10.1016/J.BBADIS.2021.166260
2021-08-26 Recognition of Divergent Viral Substrates by the SARS-CoV-2 Main Protease (edit) 10.1021/ACSINFECDIS.1C00237
2021-08-26 Phosphorylation of SARS-CoV-2 Orf9b Regulates Its Targeting to Two Binding Sites in TOM70 and Recruitment of Hsp90 (edit) 10.3390/IJMS22179233
2021-08-25 SARS-CoV-2 Membrane Glycoprotein M Triggers Apoptosis With the Assistance of Nucleocapsid Protein N in Cells (edit) 10.3389/FCIMB.2021.706252
2021-08-24 Targeted in situ cross-linking mass spectrometry and integrative modeling reveal the architectures of three proteins from SARS-CoV-2 (edit) 10.1073/PNAS.2103554118
2021-08-24 Pyroptosis of syncytia formed by fusion of SARS-CoV-2 spike and ACE2-expressing cells (edit) 10.1038/S41421-021-00310-0
2021-08-23 Multiple Roles of SARS-CoV-2 N Protein Facilitated by Proteoform-Specific Interactions with RNA, Host Proteins, and Convalescent Antibodies (edit) 10.1021/JACSAU.1C00139
2021-08-22 Cell-Free Hemoglobin Does Not Attenuate the Effects of SARS-CoV-2 Spike Protein S1 Subunit in Pulmonary Endothelial Cells (edit) 10.3390/IJMS22169041
2021-08-21 SARS-CoV-2 Proteins Bind to Hemoglobin and Its Metabolites (edit) 10.3390/IJMS22169035
2021-08-20 Genome-wide CRISPR activation screen identifies candidate receptors for SARS-CoV-2 entry (edit) 10.1007/S11427-021-1990-5
2021-08-19 A glycan gate controls opening of the SARS-CoV-2 spike protein (edit) 10.1038/S41557-021-00758-3
2021-08-17 Regulation of the Dimerization and Activity of SARS-CoV-2 Main Protease through Reversible Glutathionylation of Cysteine 300 (edit) 10.1128/MBIO.02094-21
2021-08-17 Molecular determinants for regulation of G3BP1/2 phase separation by the SARS-CoV-2 nucleocapsid protein (edit) 10.1038/S41421-021-00306-W
2021-08-16 Structure and Function of N-Terminal Zinc Finger Domain of SARS-CoV-2 NSP2 (edit) 10.1007/S12250-021-00431-6
2021-08-13 The challenge of structural heterogeneity in the native mass spectrometry studies of the SARS-CoV-2 spike protein interactions with its host cell-surface receptor (edit) 10.1007/S00216-021-03601-3
2021-08-13 The Structure-Based Design of SARS-CoV-2 nsp14 Methyltransferase Ligands Yields Nanomolar Inhibitors (edit) 10.1021/ACSINFECDIS.1C00131
2021-08-13 A distinct ssDNA/RNA binding interface in the Nsp9 protein from SARS-CoV-2 (edit) 10.1002/PROT.26205
2021-08-12 Role of ATP in the RNA Translocation Mechanism of SARS-CoV-2 NSP13 Helicase (edit) 10.1021/ACS.JPCB.1C04528
2021-08-11 Structural O-Glycoform Heterogeneity of the SARS-CoV-2 Spike Protein Receptor-Binding Domain Revealed by Top-Down Mass Spectrometry (edit) 10.1021/JACS.1C02713
2021-08-11 Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase (edit) 10.1038/S41467-021-25166-6
2021-08-10 Contribution of SARS-CoV-2 Accessory Proteins to Viral Pathogenicity in K18 Human ACE2 Transgenic Mice (edit) 10.1128/JVI.00402-21
2021-08-05 NMPylation and de-NMPylation of SARS-CoV-2 nsp9 by the NiRAN domain (edit) 10.1093/NAR/GKAB677
2021-08-03 Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication (edit) 10.1016/J.BPJ.2021.06.006
2021-08-02 SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation (edit) 10.1038/S41467-021-25015-6
2021-08-02 Why All the Fury over Furin? (edit) 10.1021/ACS.JMEDCHEM.1C00518
2021-08-01 Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors (edit) 10.1016/J.PBIOMOLBIO.2021.02.002
2021-08-01 S-acylation of SARS-CoV-2 Spike Protein: Mechanistic Dissection, In Vitro Reconstitution and Role in Viral Infectivity (edit) 10.1016/J.JBC.2021.101112
2021-08-01 Predictable fold switching by the SARS-CoV-2 protein ORF9b (edit) 10.1002/PRO.4097
2021-07-31 Heparin: A simplistic repurposing to prevent SARS-CoV-2 transmission in light of its in-vitro nanomolar efficacy (edit) 10.1016/J.IJBIOMAC.2021.04.148
2021-07-30 Quantum simulations of SARS-CoV-2 main protease M enable high-quality scoring of diverse ligands (edit) 10.1007/S10822-021-00412-7
2021-07-30 SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: Implications for microclot formation in COVID-19 (edit) 10.1042/BSR20210611
2021-07-30 Correlative multi-scale cryo-imaging unveils SARS-CoV-2 assembly and egress (edit) 10.1038/S41467-021-24887-Y
2021-07-29 Localization of SARS-CoV-2 Capping Enzymes Revealed by an Antibody against the nsp10 Subunit (edit) 10.3390/V13081487
2021-07-29 SARS-CoV-2 infection induces the activation of tissue factor-mediated coagulation via activation of acid sphingomyelinase (edit) 10.1182/BLOOD.2021010685
2021-07-28 CD209L/L-SIGN and CD209/DC-SIGN Act as Receptors for SARS-CoV-2 (edit) 10.1021/ACSCENTSCI.0C01537
2021-07-28 IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro (edit) 10.1038/S41467-021-24817-Y
2021-07-27 Structural basis of mismatch recognition by a SARS-CoV-2 proofreading enzyme (edit) 10.1126/SCIENCE.ABI9310
2021-07-27 SARS-CoV-2 infection triggers widespread host mRNA decay leading to an mRNA export block (edit) 10.1261/RNA.078923.121
2021-07-23 SARS-CoV-2 N Protein Targets TRIM25-Mediated RIG-I Activation to Suppress Innate Immunity (edit) 10.3390/V13081439
2021-07-23 The Inherent Dynamics and Interaction Sites of the SARS-CoV-2 Nucleocapsid N-Terminal Region (edit) 10.1016/J.JMB.2021.167108
2021-07-23 Experimental Evidence for Enhanced Receptor Binding by Rapidly Spreading SARS-CoV-2 Variants (edit) 10.1016/J.JMB.2021.167058
2021-07-22 L-SIGN is a receptor on liver sinusoidal endothelial cells for SARS-CoV-2 virus (edit) 10.1172/JCI.INSIGHT.148999
2021-07-22 Genome-wide analysis of protein-protein interactions and involvement of viral proteins in SARS-CoV-2 replication (edit) 10.1186/S13578-021-00644-Y
2021-07-21 The virological impacts of SARS-CoV-2 D614G mutation (edit) 10.1093/JMCB/MJAB045
2021-07-21 Lipid bilayer degradation induced by SARS-CoV-2 spike protein as revealed by neutron reflectometry (edit) 10.1038/S41598-021-93996-X
2021-07-20 Comprehensive O-Glycosylation Analysis of the SARS-CoV-2 Spike Protein with Biomimetic Trp-Arg Materials (edit) 10.1021/ACS.ANALCHEM.0C04634
2021-07-16 Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp15 endoribonuclease (edit) 10.1042/BCJ20210199
2021-07-16 Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies (edit) 10.1371/JOURNAL.PONE.0253364
2021-07-16 Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp13 helicase (edit) 10.1042/BCJ20210201
2021-07-16 Genomic characterization of SARS-CoV-2 isolates from patients in Turkey reveals the presence of novel mutations in spike and nsp12 proteins (edit) 10.1002/JMV.27188
2021-07-13 A head-to-head comparison of the inhibitory activities of 15 peptidomimetic SARS-CoV-2 3CLpro inhibitors (edit) 10.1016/J.BMCL.2021.128263
2021-07-13 Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell (edit) 10.1016/J.CELREP.2021.109364
2021-07-12 Viral MicroRNAs Encoded by Nucleocapsid Gene of SARS-CoV-2 Are Detected during Infection, and Targeting Metabolic Pathways in Host Cells (edit) 10.3390/CELLS10071762
2021-07-08 Targeting liquid–liquid phase separation of SARS-CoV-2 nucleocapsid protein promotes innate antiviral immunity by elevating MAVS activity (edit) 10.1038/S41556-021-00710-0
2021-07-07 SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction (edit) 10.1093/NAR/GKAB571
2021-07-07 Determination of intermediate state structures in the opening pathway of SARS-CoV-2 spike using cryo-electron microscopy (edit) 10.1039/D1SC00244A
2021-07-06 Kidney injury molecule-1 is a potential receptor for SARS-CoV-2 (edit) 10.1093/JMCB/MJAB003
2021-07-05 Recombinant SARS-CoV-2 envelope protein traffics to the trans-Golgi network following amphipol-mediated delivery into human cells (edit) 10.1016/J.JBC.2021.100940
2021-07-02 Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease (edit) 10.1042/BCJ20210198
2021-07-02 Implications of Spike-glycoprotein processing at S1/S2 by Furin, at S2’ by Furin and/or TMPRSS2 and shedding of ACE2: cell-to-cell fusion, cell entry and infectivity of SARS-CoV-2 (edit) 10.1101/2021.07.02.450896
2021-07-02 Site-Specific Steric Control of SARS-CoV-2 Spike Glycosylation (edit) 10.1021/ACS.BIOCHEM.1C00279
2021-07-02 Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase (edit) 10.1042/BCJ20210219
2021-07-01 Coronavirus genomic nsp14-ExoN, structure, role, mechanism, and potential application as a drug target (edit) 10.1002/JMV.27009
2021-07-01 SARS-Cov-2 spike protein fragment 674–685 protects mitochondria from releasing cytochrome c in response to apoptogenic influence (edit) 10.1016/J.BBRC.2021.05.018
2021-07-01 A weak COPI binding motif in the cytoplasmic tail of SARS-CoV-2 spike glycoprotein is necessary for its cleavage, glycosylation, and localization (edit) 10.1002/1873-3468.14109
2021-07-01 Variations in Orf3a protein of SARS-CoV-2 alter its structure and function (edit) 10.1016/J.BBREP.2021.100933
2021-07-01 Mutations in SARS-CoV-2 nsp7 and nsp8 proteins and their predicted impact on replication/transcription complex structure (edit) 10.1002/JMV.26791
2021-07-01 Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors (edit) 10.1177/24725552211026261
2021-06-30 Binding of the SARS-CoV-2 spike protein to glycans (edit) 10.1016/J.SCIB.2021.01.010
2021-06-30 Exploitation of the Secretory Pathway by SARS-CoV-2 Envelope (edit) 10.1101/2021.06.30.450614
2021-06-29 Identification of a High-Frequency Intrahost SARS-CoV-2 Spike Variant with Enhanced Cytopathic and Fusogenic Effects (edit) 10.1128/MBIO.00788-21
2021-06-29 Activation of NF-κB and induction of proinflammatory cytokine expressions mediated by ORF7a protein of SARS-CoV-2 (edit) 10.1038/S41598-021-92941-2
2021-06-29 Allosteric Activation of SARS-CoV-2 RNA-Dependent RNA Polymerase by Remdesivir Triphosphate and Other Phosphorylated Nucleotides (edit) 10.1128/MBIO.01423-21
2021-06-28 The endogenous cellular protease inhibitor SPINT2 controls SARS-CoV-2 viral infection and is associated to disease severity (edit) 10.1371/JOURNAL.PPAT.1009687
2021-06-25 Characterization of SARS-CoV-2 nucleocapsid protein reveals multiple functional consequences of the C-terminal domain (edit) 10.1016/J.ISCI.2021.102681
2021-06-25 Energetic and structural features of SARS-CoV-2 N-protein co-assemblies with nucleic acids (edit) 10.1016/J.ISCI.2021.102523
2021-06-23 TMPRSS2 expression dictates the entry route used by SARS‐CoV‐2 to infect host cells (edit) 10.15252/EMBJ.2021107821
2021-06-23 SARS-CoV-2 spike protein induces paracrine senescence and leukocyte adhesion in endothelial cells (edit) 10.1128/JVI.00794-21
2021-06-23 Deletion of ER-retention motif on SARS-CoV-2 spike protein reduces cell hybrid during cell–cell fusion (edit) 10.1186/S13578-021-00626-0
2021-06-23 Heparan Sulfate Proteoglycans as Attachment Factor for SARS-CoV-2 (edit) 10.1021/ACSCENTSCI.1C00010
2021-06-23 Nsp2 has the potential to be a drug target revealed by global identification of SARS-CoV-2 Nsp2-interacting proteins (edit) 10.1093/ABBS/GMAB088
2021-06-22 The SARS-CoV-2 Spike Protein Subunit 1 induces COVID-19-like acute lung injury in Κ18-hACE2 transgenic mice and barrier dysfunction in human endothelial cells (edit) 10.1152/AJPLUNG.00223.2021
2021-06-22 Genome‐wide association analysis of COVID‐19 mortality risk in SARS‐CoV‐2 genomes identifies mutation in the SARS‐CoV‐2 spike protein that colocalizes with P.1 of the Brazilian strain (edit) 10.1002/GEPI.22421
2021-06-22 Impact of Expressing Cells on Glycosylation and Glycan of the SARS-CoV-2 Spike Glycoprotein (edit) 10.1021/ACSOMEGA.1C01785
2021-06-22 Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs (edit) 10.1038/S41594-021-00619-0
2021-06-21 Simultaneous enrichment and separation of neutral and sialyl glycopeptides of SARS-CoV-2 spike protein enabled by dual-functionalized Ti-IMAC material (edit) 10.1007/S00216-021-03433-1
2021-06-21 Structure-function relations of the SARS-CoV-2 spike protein and impact of mutations in the variants of concern (edit) 10.5802/CRBIOL.53
2021-06-18 Heparan Sulfate Proteoglycans in Viral Infection and Treatment: A Special Focus on SARS-CoV-2 (edit) 10.3390/IJMS22126574
2021-06-16 SARS-CoV-2 NSP12 protein is not an IFN-β antagonist (edit) 10.1128/JVI.00747-21
2021-06-15 Mn2+ coordinates Cap-0-RNA to align substrates for efficient 2'--methyl transfer by SARS-CoV-2 nsp16 (edit)
2021-06-14 Molecular biology of the SARs‐CoV‐2 spike protein: A review of current knowledge (edit) 10.1002/JMV.27132
2021-06-14 Restriction of SARS-CoV-2 replication by targeting programmed −1 ribosomal frameshifting (edit) 10.1073/PNAS.2023051118
2021-06-14 Revealing the Structural Plasticity of SARS-CoV-2 nsp7 and nsp8 Using Structural Proteomics (edit) 10.1021/JASMS.1C00086
2021-06-11 Palmitoylation of SARS-CoV-2 S protein is essential for viral infectivity (edit) 10.1038/S41392-021-00651-Y
2021-06-11 Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain (edit) 10.1038/S42003-021-02250-7
2021-06-10 The SARS-CoV-2 Nucleocapsid Protein and Its Role in Viral Structure, Biological Functions, and a Potential Target for Drug or Vaccine Mitigation (edit) 10.3390/V13061115
2021-06-10 Conformational Dynamics in the Interaction of SARS-CoV-2 Papain-like Protease with Human Interferon-Stimulated Gene 15 Protein (edit) 10.1021/ACS.JPCLETT.1C00831
2021-06-10 SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target (edit) 10.1038/S41422-021-00519-4
2021-06-10 SARS-CoV-2 Nonstructural Protein 1 Inhibits the Interferon Response by Causing Depletion of Key Host Signaling Factors (edit) 10.1128/JVI.00266-21
2021-06-10 Mechanism of Inhibition of the Reproduction of SARS-CoV-2 and Ebola Viruses by Remdesivir (edit) 10.1021/ACS.BIOCHEM.1C00292
2021-06-10 Conformational dynamics of 13 amino acids long NSP11 of SARS-CoV-2 under membrane mimetics and different solvent conditions (edit) 10.1016/J.MICPATH.2021.105041
2021-06-09 Endothelial glycocalyx shields the interaction of SARS-CoV-2 spike protein with ACE2 receptors (edit) 10.1038/S41598-021-91231-1
2021-06-09 SARS-CoV-2 Envelope (E) protein interacts with PDZ-domain-2 of host tight junction protein ZO1 (edit) 10.1371/JOURNAL.PONE.0251955
2021-06-09 Screening of FDA-approved compound library identifies potential small-molecule inhibitors of SARS-CoV-2 non-structural proteins NSP1, NSP4, NSP6 and NSP13: molecular modeling and molecular dynamics studies (edit) 10.1007/S42485-021-00067-W
2021-06-08 SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2 (edit) 10.1016/J.IMMUNI.2021.05.006
2021-06-08 Structural basis for SARS-CoV-2 envelope protein recognition of human cell junction protein PALS1 (edit) 10.1038/S41467-021-23533-X
2021-06-07 Cell entry by SARS-CoV-2 (edit) 10.1016/J.TIBS.2021.06.001
2021-06-07 ACE2-Independent Interaction of SARS-CoV-2 Spike Protein with Human Epithelial Cells Is Inhibited by Unfractionated Heparin (edit) 10.3390/CELLS10061419
2021-06-07 Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant (edit) 10.1101/2021.06.06.446826
2021-06-03 Fe-S cofactors in the SARS-CoV-2 RNA-dependent RNA polymerase are potential antiviral targets (edit) 10.1126/SCIENCE.ABI5224
2021-06-02 A metal ion orients SARS-CoV-2 mRNA to ensure accurate 2′-O methylation of its first nucleotide (edit) 10.1038/S41467-021-23594-Y
2021-06-02 Epigallocatechin Gallate Inhibits the Uridylate-Specific Endoribonuclease Nsp15 and Efficiently Neutralizes the SARS-CoV-2 Strain (edit) 10.1021/ACS.JAFC.1C02050
2021-06-02 Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry (edit) 10.1016/J.YMTHE.2021.02.007
2021-06-02 Surface Proteins of SARS-CoV-2 Drive Airway Epithelial Cells to Induce IFN-Dependent Inflammation (edit) 10.4049/JIMMUNOL.2001407
2021-06-01 A High-Throughput RNA Displacement Assay for Screening SARS-CoV-2 nsp10-nsp16 Complex toward Developing Therapeutics for COVID-19 (edit) 10.1177/2472555220985040
2021-06-01 A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process (edit) 10.1016/J.JMB.2021.167118
2021-06-01 Why do SARS-CoV-2 NSPs rush to the ER? (edit) 10.1007/S00415-020-10197-8
2021-06-01 Neuropilin-1 Assists SARS-CoV-2 Infection by Stimulating the Separation of Spike Protein Domains S1 and S2 (edit) 10.1016/J.BPJ.2021.05.026
2021-06-01 Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia (edit) 10.1038/S41586-021-03491-6
2021-06-01 SARS-CoV-2 mutation 614G creates an elastase cleavage site enhancing its spread in high AAT-deficient regions (edit) 10.1016/J.MEEGID.2021.104760
2021-06-01 Multiple sites on SARS-CoV-2 spike protein are susceptible to proteolysis by cathepsins B, K, L, S, and V (edit) 10.1002/PRO.4073
2021-06-01 The envelope protein of SARS-CoV-2 increases intra-Golgi pH and forms a cation channel that is regulated by pH (edit) 10.1113/JP281037
2021-06-01 Characterization of the SARS-CoV-2 E Protein: Sequence, Structure, Viroporin, and Inhibitors (edit) 10.1002/PRO.4075
2021-06-01 Transport mechanisms of SARS-CoV-E viroporin in calcium solutions: Lipid-dependent Anomalous Mole Fraction Effect and regulation of pore conductance (edit) 10.1016/J.BBAMEM.2021.183590
2021-06-01 SARS-CoV-2 genomic surveillance identifies naturally occurring truncation of ORF7a that limits immune suppression (edit) 10.1016/J.CELREP.2021.109197
2021-06-01 Structure and function of SARS-CoV-2 polymerase (edit) 10.1016/J.COVIRO.2021.03.010
2021-06-01 Piece of the puzzle: Remdesivir disassembles the multimeric SARS-CoV-2 RNA-dependent RNA polymerase complex (edit) 10.1007/S12013-021-00977-Y
2021-05-31 Revealing the host antiviral protein ZAP-S as an inhibitor of SARS-CoV-2 programmed ribosomal frameshifting (edit) 10.1101/2021.05.31.445667
2021-05-28 ALG-097111, a potent and selective SARS-CoV-2 3-chymotrypsin-like cysteine protease inhibitor exhibits in vivo efficacy in a Syrian Hamster model (edit) 10.1016/J.BBRC.2021.03.096
2021-05-28 Probing effects of the SARS-CoV-2 E protein on membrane curvature and intracellular calcium (edit) 10.1101/2021.05.28.446179
2021-05-27 Translational shutdown and evasion of the innate immune response by SARS-CoV-2 NSP14 protein (edit) 10.1073/PNAS.2101161118
2021-05-27 Identification of SARS-CoV-2 Receptor Binding Inhibitors by In Vitro Screening of Drug Libraries (edit) 10.3390/MOLECULES26113213
2021-05-27 NPC1-regulated dynamic of clathrin-coated pits is essential for viral entry (edit) 10.1007/S11427-021-1929-Y
2021-05-26 Similarities and differences in the conformational stability and reversibility of ORF8, an accessory protein of SARS-CoV-2, and its L84S variant (edit) 10.1016/J.BBRC.2021.05.074
2021-05-25 2'-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography (edit) 10.1073/PNAS.2100170118
2021-05-25 SARS-CoV-2 nucleocapsid protein impairs stress granule formation to promote viral replication (edit) 10.1038/S41421-021-00275-0
2021-05-25 Azelastine inhibits viropexis of SARS-CoV-2 spike pseudovirus by binding to SARS-CoV-2 entry receptor ACE2 (edit)
2021-05-24 Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading (edit) 10.1016/J.CELL.2021.05.033
2021-05-24 SARS-CoV-2 simulations go exascale to predict dramatic spike opening and cryptic pockets across the proteome (edit) 10.1038/S41557-021-00707-0
2021-05-22 Glycosylation is a key in SARS-CoV-2 infection (edit) 10.1007/S00109-021-02092-0
2021-05-21 Crystal structure of SARS-CoV-2 nsp10 bound to nsp14-ExoN domain reveals an exoribonuclease with both structural and functional integrity (edit) 10.1093/NAR/GKAB320
2021-05-21 Viewing SARS-CoV-2 Nucleocapsid Protein in Terms of Molecular Flexibility (edit) 10.3390/BIOLOGY10060454
2021-05-21 The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι (edit) 10.1073/PNAS.2024202118
2021-05-19 Contribution of Syndecans to the Cellular Entry of SARS-CoV-2 (edit) 10.3390/IJMS22105336
2021-05-18 Hepatitis C virus drugs that inhibit SARS-CoV-2 papain-like protease synergize with remdesivir to suppress viral replication in cell culture (edit) 10.1016/J.CELREP.2021.109133
2021-05-18 ZMPSTE24 Regulates SARS-CoV-2 Spike Protein-enhanced Expression of Endothelial Plasminogen Activator Inhibitor-1 (edit) 10.1165/RCMB.2020-0544OC
2021-05-18 Disruption of disulfides within RBD of SARS‐CoV‐2 spike protein prevents fusion and represents a target for viral entry inhibition by registered drugs (edit) 10.1096/FJ.202100560R
2021-05-18 Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity (edit) 10.1371/JOURNAL.PPAT.1009519
2021-05-17 Two conserved oligomer interfaces of NSP7 and NSP8 underpin the dynamic assembly of SARS-CoV-2 RdRP (edit) 10.1093/NAR/GKAB370
2021-05-15 The human pandemic coronaviruses on the show: The spike glycoprotein as the main actor in the coronaviruses play (edit) 10.1016/J.IJBIOMAC.2021.02.203
2021-05-15 Heparan sulfates from bat and human lung and their binding to the spike protein of SARS-CoV-2 virus (edit) 10.1016/J.CARBPOL.2021.117797
2021-05-14 SARS-CoV-2 Fusion Peptide has a Greater Membrane Perturbating Effect than SARS-CoV with Highly Specific Dependence on Ca (edit) 10.1016/J.JMB.2021.166946
2021-05-14 Glucosidase inhibitors suppress SARS-CoV-2 in tissue culture and may potentiate (edit) 10.1101/2021.05.14.444190
2021-05-14 Crystal structure of SARS-CoV-2 Orf9b in complex with human TOM70 suggests unusual virus-host interactions (edit) 10.1038/S41467-021-23118-8
2021-05-13 Variable post-translational modifications of SARS-CoV-2 nucleocapsid protein (edit) 10.1093/GLYCOB/CWAB044
2021-05-11 A SARS-CoV-2 antibody curbs viral nucleocapsid protein-induced complement hyperactivation (edit) 10.1038/S41467-021-23036-9
2021-05-11 Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex (edit) 10.1073/PNAS.2102516118
2021-05-11 Plant-derived exosomal microRNAs inhibit lung inflammation induced by exosomes SARS-CoV-2 Nsp12 (edit) 10.1016/J.YMTHE.2021.05.005
2021-05-10 A comprehensive library of fluorescent constructs of SARS‐CoV‐2 proteins and their initial characterisation in different cell types (edit) 10.1111/BOC.202000158
2021-05-10 Deletion of the SARS-CoV-2 Spike Cytoplasmic Tail Increases Infectivity in Pseudovirus Neutralization Assays (edit) 10.1128/JVI.00044-21
2021-05-07 X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease (edit) 10.1126/SCIENCE.ABF7945
2021-05-07 TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines (edit) 10.1038/S41590-021-00937-X
2021-05-04 The SARS-CoV-2 protein ORF3a inhibits fusion of autophagosomes with lysosomes (edit) 10.1038/S41421-021-00268-Z
2021-05-01 Arginine Methylation of SARS-Cov-2 Nucleocapsid Protein Regulates RNA Binding, its Ability to Suppress Stress Granule Formation and Viral Replication (edit) 10.1016/J.JBC.2021.100821
2021-05-01 Human SARS CoV-2 spike protein mutations (edit) 10.1002/PROT.26042
2021-05-01 DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist (edit) 10.1371/JOURNAL.PPAT.1009576
2021-05-01 SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity (edit) 10.1126/SCIADV.ABG7607
2021-05-01 Interferon antagonism by SARS-CoV-2: a functional study using reverse genetics (edit) 10.1016/S2666-5247(21)00027-6
2021-04-30 SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2 (edit) 10.1161/CIRCRESAHA.121.318902
2021-04-29 Reconstitution and functional characterization of SARS-CoV-2 proofreading complex (edit) 10.1016/J.PEP.2021.105894
2021-04-29 SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies (edit) 10.1016/J.CELL.2021.03.036
2021-04-29 Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity (edit) 10.1016/J.CELL.2021.03.013
2021-04-29 SARS-CoV-2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING signaling pathways (edit) 10.1002/JMV.27050
2021-04-28 Coiled-coil heterodimers with increased stability for cellular regulation and sensing SARS-CoV-2 spike protein-mediated cell fusion (edit) 10.1038/S41598-021-88315-3
2021-04-27 The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets (edit) 10.1038/S41564-021-00908-W
2021-04-27 ORF10-Cullin-2-ZYG11B complex is not required for SARS-CoV-2 infection (edit) 10.1073/PNAS.2023157118
2021-04-24 RNA-induced liquid phase separation of SARS-CoV-2 nucleocapsid protein facilitates NF-κB hyper-activation and inflammation (edit) 10.1038/S41392-021-00575-7
2021-04-23 SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation (edit) 10.7554/ELIFE.65962
2021-04-23 ORF8 contributes to cytokine storm during SARS-CoV-2 infection by activating IL-17 pathway (edit) 10.1016/J.ISCI.2021.102293
2021-04-22 High-throughput screening of the ReFRAME, Pandemic Box, and COVID Box drug repurposing libraries against SARS-CoV-2 nsp15 endoribonuclease to identify small-molecule inhibitors of viral activity (edit) 10.1371/JOURNAL.PONE.0250019
2021-04-20 The SARS‐unique domain (SUD) of SARS‐CoV and SARS‐CoV‐2 interacts with human Paip1 to enhance viral RNA translation (edit) 10.15252/EMBJ.2019102277
2021-04-20 SARS-CoV-2 spike protein dictates syncytium-mediated lymphocyte elimination (edit) 10.1038/S41418-021-00782-3
2021-04-16 The Mechanism of SARS-CoV-2 Nucleocapsid Protein Recognition by the Human 14-3-3 Proteins (edit) 10.1016/J.JMB.2021.166875
2021-04-15 Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system (edit) 10.1016/J.CELL.2021.02.053
2021-04-15 A unique view of SARS-COV-2 through the lens of ORF8 protein (edit) 10.1016/J.COMPBIOMED.2021.104380
2021-04-13 SARS-CoV-2 ORF6 Disrupts Bidirectional Nucleocytoplasmic Transport through Interactions with Rae1 and Nup98 (edit) 10.1128/MBIO.00065-21
2021-04-12 SARS-CoV-2 and SARS-CoV Spike-Mediated Cell-Cell Fusion Differ in Their Requirements for Receptor Expression and Proteolytic Activation (edit) 10.1128/JVI.00002-21
2021-04-12 The Polybasic Cleavage Site in SARS-CoV-2 Spike Modulates Viral Sensitivity to Type I Interferon and IFITM2 (edit) 10.1128/JVI.02422-20
2021-04-09 Human airway cells prevent SARS-CoV-2 multibasic cleavage site cell culture adaptation (edit) 10.7554/ELIFE.66815
2021-04-09 The Spike Glycoprotein of SARS-CoV-2 Binds to β1 Integrins Expressed on the Surface of Lung Epithelial Cells (edit) 10.3390/V13040645
2021-04-08 Structural Insights into Plasticity and Discovery of Remdesivir Metabolite GS-441524 Binding in SARS-CoV-2 Macrodomain (edit) 10.1021/ACSMEDCHEMLETT.0C00684
2021-04-07 The SARS-CoV-2 Nsp3 macrodomain reverses PARP9/DTX3L-dependent ADP-ribosylation induced by interferon signalling (edit) 10.1101/2021.04.06.438552
2021-04-05 Repositioning of histamine H receptor antagonist: Doxepin inhibits viropexis of SARS-CoV-2 Spike pseudovirus by blocking ACE2 (edit) 10.1016/J.EJPHAR.2021.173897
2021-04-04 Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN (edit) 10.1101/2021.04.02.438274
2021-04-01 Nucleocapsid and Spike Proteins of SARS-CoV-2 Drive Neutrophil Extracellular Trap Formation (edit) 10.4110/IN.2021.21.E16
2021-04-01 The highly flexible disordered regions of the SARS-CoV-2 nucleocapsid N protein within the 1-248 residue construct: sequence-specific resonance assignments through NMR (edit) 10.1007/S12104-021-10009-8
2021-04-01 ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity (edit) 10.1038/S41564-021-00884-1
2021-04-01 Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking (edit) 10.1126/SCIADV.ABF8711
2021-04-01 H, C and N backbone chemical shift assignments of SARS-CoV-2 nsp3a (edit) 10.1007/S12104-020-10001-8
2021-04-01 Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia (edit) 10.1016/J.CELL.2021.04.033
2021-04-01 Testing of the inhibitory effects of loratadine and desloratadine on SARS-CoV-2 spike pseudotyped virus viropexis (edit) 10.1016/J.CBI.2021.109420
2021-04-01 The Role of the SARS-CoV-2 S-Protein Glycosylation in the Interaction of SARS-CoV-2/ACE2 and Immunological Responses (edit) 10.1089/VIM.2020.0174
2021-04-01 Analysis of glycosylation and disulfide bonding of wild-type SARS-CoV-2 spike glycoprotein (edit) 10.1101/2021.04.01.438120
2021-04-01 The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airways (edit) 10.1371/JOURNAL.PPAT.1009500
2021-04-01 Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry (edit) 10.1101/2021.03.31.437960
2021-04-01 Crystallographic molecular replacement using an in silico-generated search model of SARS-CoV-2 ORF8 (edit) 10.1002/PRO.4050
2021-04-01 The ORF8 protein of SARS-CoV-2 induced endoplasmic reticulum stress and mediated immune evasion by antagonizing production of interferon beta (edit) 10.1016/J.VIRUSRES.2021.198350
2021-03-29 Multivalent binding of the partially disordered SARS-CoV-2 nucleocapsid phosphoprotein dimer to RNA (edit) 10.1016/J.BPJ.2021.03.023
2021-03-29 The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA (edit) 10.1038/S41467-021-21953-3
2021-03-29 SARS-CoV-2 Nsp16 activation mechanism and a cryptic pocket with pan-coronavirus antiviral potential (edit) 10.1016/J.BPJ.2021.03.024
2021-03-27 Cathepsin L plays a key role in SARS-CoV-2 infection in humans and humanized mice and is a promising target for new drug development (edit) 10.1038/S41392-021-00558-8
2021-03-27 The nucleotide addition cycle of the SARS-CoV-2 polymerase (edit) 10.1101/2021.03.27.437309
2021-03-26 Understanding the phase separation characteristics of nucleocapsid protein provides a new therapeutic opportunity against SARS-CoV-2 (edit) 10.1007/S13238-021-00832-Z
2021-03-26 SARS-CoV-2 M inhibitors with antiviral activity in a transgenic mouse model (edit) 10.1126/SCIENCE.ABF1611
2021-03-25 Site-Specific O-Glycosylation Analysis of SARS-CoV-2 Spike Protein Produced in Insect and Human Cells (edit) 10.3390/V13040551
2021-03-25 Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor (edit) 10.1186/S13578-021-00568-7
2021-03-25 Functional analysis of SARS-CoV-2 proteins in Drosophila identifies Orf6-induced pathogenic effects with Selinexor as an effective treatment (edit) 10.1186/S13578-021-00567-8
2021-03-25 In silico studies of selected multi-drug targeting against 3CLpro and nsp12 RNA-dependent RNA-polymerase proteins of SARS-CoV-2 and SARS-CoV (edit) 10.1007/S13721-021-00299-2
2021-03-24 Arginine Methylation Regulates SARS-CoV-2 Nucleocapsid Protein Function and Viral Replication (edit) 10.1101/2021.03.24.436822
2021-03-24 Topography, Spike Dynamics, and Nanomechanics of Individual Native SARS-CoV-2 Virions (edit) 10.1021/ACS.NANOLETT.0C04465
2021-03-24 Inhibition of HECT E3 ligases as potential therapy for COVID-19 (edit) 10.1038/S41419-021-03513-1
2021-03-23 SARS-CoV-2 variants lacking ORF8 occurred in farmed mink and pangolin (edit) 10.1016/J.GENE.2021.145596
2021-03-19 Mass spectrometric based detection of protein nucleotidylation in the RNA polymerase of SARS-CoV-2 (edit) 10.1038/S42004-021-00476-4
2021-03-18 Sialic acid-Dependent Binding and Viral Entry of SARS-CoV-2 (edit) 10.21203/RS.3.RS-318912/V1
2021-03-18 Identification of guanylyltransferase activity in the SARS-CoV-2 RNA polymerase (edit) 10.1101/2021.03.17.435913
2021-03-16 Ca-dependent mechanism of membrane insertion and destabilization by the SARS-CoV-2 fusion peptide (edit) 10.1016/J.BPJ.2021.02.023
2021-03-16 Neutrophil Elastase and Proteinase 3 Cleavage Sites Are Adjacent to the Polybasic Sequence within the Proteolytic Sensitive Activation Loop of the SARS-CoV-2 Spike Protein (edit) 10.1021/ACSOMEGA.1C00363
2021-03-15 Unique and complementary suppression of cGAS-STING and RNA sensing- triggered innate immune responses by SARS-CoV-2 proteins (edit) 10.1038/S41392-021-00515-5
2021-03-15 SARS-CoV-2 Nsp8 N-terminal domain dimerizes and harbors autonomously folded elements (edit) 10.1101/2021.03.12.435186
2021-03-15 Structure, Mechanism and Crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase (edit) 10.1101/2021.03.15.435326
2021-03-12 Contribution of SARS-CoV-2 accessory proteins to viral pathogenicity in K18 hACE2 transgenic mice (edit) 10.1101/2021.03.09.434696
2021-03-11 New targets for drug design: importance of nsp14/nsp10 complex formation for the 3'-5' exoribonucleolytic activity on SARS-CoV-2 (edit) 10.1111/FEBS.15815
2021-03-11 Immunoinformatic analysis of structural and epitope variations in the spike and Orf8 proteins of SARS-CoV-2/B.1.1.7 (edit)
2021-03-11 SARS-CoV-2 non-structural protein 13 (nsp13) hijacks host deubiquitinase USP13 and counteracts host antiviral immune response (edit) 10.1038/S41392-021-00509-3
2021-03-10 Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies (edit) 10.1016/J.CHOM.2021.02.003
2021-03-10 Genomic monitoring of SARS-CoV-2 uncovers an Nsp1 deletion variant that modulates type I interferon response (edit) 10.1016/J.CHOM.2021.01.015
2021-03-08 Genome-wide CRISPR screening identifies TMEM106B as a proviral host factor for SARS-CoV-2 (edit) 10.1038/S41588-021-00805-2
2021-03-05 Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2 (edit) 10.1101/2021.03.05.434000
2021-03-05 RNA-dependent RNA polymerase (RdRp) inhibitors: The current landscape and repurposing for the COVID-19 pandemic (edit) 10.1016/J.EJMECH.2021.113201
2021-03-03 Heterogeneity of Glycan Processing on Trimeric SARS-CoV-2 Spike Protein Revealed by Charge Detection Mass Spectrometry (edit) 10.1021/JACS.1C00353
2021-03-03 The SARS-CoV-2 receptor-binding domain preferentially recognizes blood group A (edit) 10.1182/BLOODADVANCES.2020003259
2021-03-02 SARS-CoV-2 Nucleocapsid Protein Targets RIG-I-Like Receptor Pathways to Inhibit the Induction of Interferon Response (edit) 10.3390/CELLS10030530
2021-03-02 Enhanced Cholesterol-Dependent Hemifusion by Internal Fusion Peptide 1 of SARS Coronavirus-2 Compared to Its N-Terminal Counterpart (edit) 10.1021/ACS.BIOCHEM.1C00046
2021-03-01 Dual inhibition of SARS-CoV-2 and human rhinovirus with protease inhibitors in clinical development (edit) 10.1016/J.ANTIVIRAL.2021.105020
2021-03-01 Structural O-Glycoform Heterogeneity of the SARS-CoV-2 Spike Protein Receptor-Binding Domain Revealed by Native Top-Down Mass Spectrometry (edit) 10.1101/2021.02.28.433291
2021-03-01 Ubiquitination of SARS-CoV-2 ORF7a promotes antagonism of interferon response (edit) 10.1038/S41423-020-00603-6
2021-03-01 Structural insight reveals SARS-CoV-2 ORF7a as an immunomodulating factor for human CD14+ monocytes (edit) 10.1016/J.ISCI.2021.102187
2021-03-01 Whole genome analysis of more than 10 000 SARS-CoV-2 virus unveils global genetic diversity and target region of NSP6 (edit) 10.1093/BIB/BBAB025
2021-03-01 Hallmarks of Alpha- and Betacoronavirus non-structural protein 7+8 complexes (edit) 10.1126/SCIADV.ABF1004
2021-02-28 TMPRSS11D and TMPRSS13 Activate the SARS-CoV-2 Spike Protein (edit) 10.3390/V13030384
2021-02-26 SARS-CoV-2 Nonstructural Proteins 1 and 13 Suppress Caspase-1 and the NLRP3 Inflammasome Activation (edit) 10.3390/MICROORGANISMS9030494
2021-02-26 SARS-CoV-2 nsp12 attenuates type I interferon production by inhibiting IRF3 nuclear translocation (edit) 10.1038/S41423-020-00619-Y
2021-02-24 A Biochemical Perspective of the Nonstructural Proteins (NSPs) and the Spike Protein of SARS CoV-2 (edit) 10.1007/S10930-021-09967-8
2021-02-24 SARS-CoV-2 genomic surveillance identifies naturally occurring truncations of ORF7a that limit immune suppression (edit) 10.1101/2021.02.22.21252253
2021-02-24 SARS-CoV-2 ORF6 disturbs nucleocytoplasmic trafficking to advance the viral replication (edit) 10.1101/2021.02.24.432656
2021-02-23 The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation (edit) 10.1101/2021.02.23.432450
2021-02-23 Structural and functional characterization of SARS-CoV-2 RBD domains produced in mammalian cells (edit) 10.1101/2021.02.23.432424
2021-02-22 Identification and functional analysis of the SARS-COV-2 nucleocapsid protein (edit) 10.1186/S12866-021-02107-3
2021-02-22 ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation (edit) 10.1016/J.DEVCEL.2020.12.010
2021-02-19 Probing the SAM Binding Site of SARS-CoV-2 nsp14 in vitro Using SAM Competitive Inhibitors Guides Developing Selective bi-substrate Inhibitors (edit) 10.1101/2021.02.19.424337
2021-02-18 SARS-CoV-2 nucleocapsid protein dually regulates innate immune responses (edit) 10.1101/2021.02.17.431755
2021-02-18 Direct activation of endothelial cells by SARS-CoV-2 nucleocapsid protein is blocked by Simvastatin (edit) 10.1101/2021.02.14.431174
2021-02-12 Proteolytic Activation of SARS-CoV-2 Spike at the S1/S2 Boundary: Potential Role of Proteases beyond Furin (edit) 10.1021/ACSINFECDIS.0C00701
2021-02-11 Identification of ebselen and its analogues as potent covalent inhibitors of papain-like protease from SARS-CoV-2 (edit) 10.1038/S41598-021-83229-6
2021-02-11 A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry (edit) 10.1038/S41467-021-21213-4
2021-02-09 Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2 (edit) 10.1038/S42003-021-01735-9
2021-02-09 Energetic and structural features of SARS-CoV-2 N-protein co-assemblies with nucleic acids (edit) 10.1101/2021.02.08.430344
2021-02-09 Dynamic competition between SARS-CoV-2 NSP1 and mRNA on the human ribosome inhibits translation initiation (edit) 10.1073/PNAS.2017715118
2021-02-09 Coronavirus replication-transcription complex: Vital and selective NMPylation of a conserved site in nsp9 by the NiRAN-RdRp subunit (edit) 10.1073/PNAS.2022310118
2021-02-08 SARS-CoV-2 S protein:ACE2 interaction reveals novel allosteric targets (edit) 10.7554/ELIFE.63646
2021-02-07 Targeting CTP Synthetase 1 to Restore Interferon Induction and Impede Nucleotide Synthesis in SARS-CoV-2 Infection (edit) 10.1101/2021.02.05.429959
2021-02-05 Protein glycosylation is essential for SARS-CoV-2 infection (edit) 10.1101/2021.02.05.429940
2021-02-05 SARS-CoV-2 ORF7b: is a bat virus protein homologue a major cause of COVID-19 symptoms? (edit) 10.1101/2021.02.05.428650
2021-02-04 Targeted in situ cross-linking mass spectrometry and integrative modeling reveal the architectures of Nsp1, Nsp2, and Nucleocapsid proteins from SARS-CoV-2 (edit) 10.1101/2021.02.04.429751
2021-02-02 Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors (edit) 10.1038/S41467-021-21060-3
2021-02-02 Mechanisms of Coronavirus Nsp1-Mediated Control of Host and Viral Gene Expression (edit) 10.3390/CELLS10020300
2021-02-01 Mn2+ coordinates Cap-0-RNA to align substrates for efficient 2′-O-methyl transfer by SARS-CoV-2 nsp16 (edit) 10.1101/2021.01.31.429023
2021-02-01 SARS-CoV-2 spike protein S1 subunit induces pro-inflammatory responses via toll-like receptor 4 signaling in murine and human macrophages (edit) 10.1016/J.HELIYON.2021.E06187
2021-02-01 Multimerization- and glycosylation-dependent receptor binding of SARS-CoV-2 spike proteins (edit) 10.1371/JOURNAL.PPAT.1009282
2021-02-01 Cold sensitivity of the SARS-CoV-2 spike ectodomain (edit) 10.1038/S41594-020-00547-5
2021-02-01 Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression (edit) 10.1126/SCIADV.ABE7386
2021-02-01 SARS-CoV-2 ORF9b inhibits RIG-I-MAVS antiviral signaling by interrupting K63-linked ubiquitination of NEMO (edit) 10.1016/J.CELREP.2021.108761
2021-02-01 Structural Basis of SARS-CoV-2 Polymerase Inhibition by Favipiravir (edit) 10.1016/J.XINN.2021.100080
2021-02-01 Force-Dependent Stimulation of RNA Unwinding by SARS-CoV-2 NSP13 Helicase (edit) 10.1016/J.BPJ.2020.11.772
2021-01-29 RNA-dependent RNA polymerase: Structure, mechanism, and drug discovery for COVID-19 (edit) 10.1016/J.BBRC.2020.08.116
2021-01-28 A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication (edit) 10.1038/S41467-021-20900-6
2021-01-28 D614G Substitution of SARS-CoV-2 Spike Protein Increases Syncytium Formation and Viral Transmission via Enhanced Furin-mediated Spike Cleavage (edit) 10.1101/2021.01.27.428541
2021-01-27 Cryo-EM structures of the SARS-CoV-2 endoribonuclease Nsp15 reveal insight into nuclease specificity and dynamics (edit) 10.1038/S41467-020-20608-Z
2021-01-25 Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis (edit) 10.1038/S41586-021-03237-4
2021-01-22 In silico evaluation of lapachol derivatives binding to the Nsp9 of SARS-CoV-2 (edit) 10.1080/07391102.2021.1875050
2021-01-21 SARS-CoV-2 nucleocapsid protein undergoes liquid-liquid phase separation into stress granules through its N-terminal intrinsically disordered region (edit) 10.1038/S41421-020-00240-3
2021-01-21 The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein (edit) 10.1038/S41467-020-20768-Y
2021-01-21 Insight into molecular characteristics of SARS-CoV-2 spike protein following D614G point mutation, a molecular dynamics study (edit) 10.1080/07391102.2021.1872418
2021-01-20 The complex structure of GRL0617 and SARS-CoV-2 PLpro reveals a hot spot for antiviral drug discovery (edit) 10.1038/S41467-020-20718-8
2021-01-20 Biological and Clinical Consequences of Integrin Binding via a Rogue RGD Motif in the SARS CoV-2 Spike Protein (edit) 10.3390/V13020146
2021-01-18 Fluorescent Glycan Fingerprinting of SARS2 Spike Proteins (edit) 10.1101/2021.01.16.426965
2021-01-15 Nucleocapsid and Spike Proteins of the Coronavirus SARS-CoV-2 Induce IL6 in Monocytes and Macrophages-Potential Implications for Cytokine Storm Syndrome (edit) 10.3390/VACCINES9010054
2021-01-12 Structural Insight Into the SARS-CoV-2 Nucleocapsid Protein C-Terminal Domain Reveals a Novel Recognition Mechanism for Viral Transcriptional Regulatory Sequences (edit) 10.3389/FCHEM.2020.624765
2021-01-12 Snake venom phospholipases A2 possess a strong virucidal activity against SARS-CoV-2 in vitro and block the cell fusion mediated by spike glycoprotein interaction with the ACE2 receptor (edit) 10.1101/2021.01.12.426042
2021-01-12 Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis (edit) 10.1021/ACSOMEGA.0C03512
2021-01-11 No evidence for basigin/CD147 as a direct SARS-CoV-2 spike binding receptor (edit) 10.1038/S41598-020-80464-1
2021-01-11 Stabilizing the closed SARS-CoV-2 spike trimer (edit) 10.1038/S41467-020-20321-X
2021-01-11 Functional Analysis of SARS-CoV-2 Proteins in Drosophila Identifies Orf6-induced Pathogenicity Attenuated by Selinexor (edit) 10.21203/RS.3.RS-141269/V1
2021-01-08 AXL is a candidate receptor for SARS-CoV-2 that promotes infection of pulmonary and bronchial epithelial cells (edit) 10.1038/S41422-020-00460-Y
2021-01-07 New targets for drug design: Importance of nsp14/nsp10 complex formation for the 3’-5’ exoribonucleolytic activity on SARS-CoV-2 (edit) 10.1101/2021.01.07.425745
2021-01-06 N- and O-Glycosylation of the SARS-CoV-2 Spike Protein (edit) 10.1021/ACS.ANALCHEM.0C03173
2021-01-03 Recent advancements in glycoproteomic studies: Glycopeptide enrichment and derivatization, characterization of glycosylation in SARS CoV2, and interacting glycoproteins (edit) 10.1002/MAS.21679
2021-01-01 SARS-CoV-2 main protease suppresses type I interferon production by preventing nuclear translocation of phosphorylated IRF3 (edit) 10.7150/IJBS.59943
2021-01-01 SARS-CoV-2 nucleocapsid protein phase separates with G3BPs to disassemble stress granules and facilitate viral production (edit) 10.1016/J.SCIB.2021.01.013
2021-01-01 SARS-CoV-2 N Protein Induces Acute Lung Injury in Mice NF-ĸB Activation (edit) 10.3389/FIMMU.2021.791753
2021-01-01 Spatial and temporal roles of SARS-CoV PLpro -A snapshot (edit) 10.1096/FJ.202002271
2021-01-01 Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs (edit) 10.1016/J.MCPRO.2021.100120
2021-01-01 Human Surfactant Protein D Binds Spike Protein and Acts as an Entry Inhibitor of SARS-CoV-2 Pseudotyped Viral Particles (edit) 10.3389/FIMMU.2021.641360
2021-01-01 Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion (edit) 10.1371/JOURNAL.PPAT.1009246
2021-01-01 The Case for S2: The Potential Benefits of the S2 Subunit of the SARS-CoV-2 Spike Protein as an Immunogen in Fighting the COVID-19 Pandemic (edit) 10.3389/FIMMU.2021.637651
2021-01-01 Glycans of SARS-CoV-2 Spike Protein in Virus Infection and Antibody Production (edit) 10.3389/FMOLB.2021.629873
2021-01-01 Heparan Sulfate Facilitates Spike Protein-Mediated SARS-CoV-2 Host Cell Invasion and Contributes to Increased Infection of SARS-CoV-2 G614 Mutant and in Lung Cancer (edit) 10.3389/FMOLB.2021.649575
2021-01-01 SARS-CoV-2 Spike Protein Induces Degradation of Junctional Proteins That Maintain Endothelial Barrier Integrity (edit) 10.3389/FCVM.2021.687783
2021-01-01 SARS-CoV-2 variants with mutations at the S1/S2 cleavage site are generated in vitro during propagation in TMPRSS2-deficient cells (edit) 10.1371/JOURNAL.PPAT.1009233
2021-01-01 The Importance of Glycosylation in COVID-19 Infection (edit)
2021-01-01 O-Glycosylation Landscapes of SARS-CoV-2 Spike Proteins (edit) 10.3389/FCHEM.2021.689521
2021-01-01 Site-Specific Glycosylation Patterns of the SARS-CoV-2 Spike Protein Derived From Recombinant Protein and Viral WA1 and D614G Strains (edit) 10.3389/FCHEM.2021.767448
2021-01-01 Metformin Suppresses Monocyte Immunometabolic Activation by SARS-CoV-2 Spike Protein Subunit 1 (edit) 10.3389/FIMMU.2021.733921
2021-01-01 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Membrane (M) and Spike (S) Proteins Antagonize Host Type I Interferon Response (edit) 10.3389/FCIMB.2021.766922
2021-01-01 Cholesterol-Rich Lipid Rafts as Platforms for SARS-CoV-2 Entry (edit) 10.3389/FIMMU.2021.796855
2021-01-01 Dependence of SARS-CoV-2 infection on cholesterol-rich lipid raft and endosomal acidification (edit) 10.1016/J.CSBJ.2021.04.001
2021-01-01 COVID-19 and Toll-Like Receptor 4 (TLR4): SARS-CoV-2 May Bind and Activate TLR4 to Increase ACE2 Expression, Facilitating Entry and Causing Hyperinflammation (edit) 10.1155/2021/8874339
2021-01-01 SARS-CoV-2 Spike Antagonizes Innate Antiviral Immunity by Targeting Interferon Regulatory Factor 3 (edit) 10.3389/FCIMB.2021.789462
2021-01-01 SARS-CoV-2 uses major endothelial integrin αvβ3 to cause vascular dysregulation in-vitro during COVID-19 (edit) 10.1371/JOURNAL.PONE.0253347
2021-01-01 ORF3a-Mediated Incomplete Autophagy Facilitates Severe Acute Respiratory Syndrome Coronavirus-2 Replication (edit) 10.3389/FCELL.2021.716208
2021-01-01 SARS-CoV-2 Membrane Protein Inhibits Type I Interferon Production Through Ubiquitin-Mediated Degradation of TBK1 (edit) 10.3389/FIMMU.2021.662989
2021-01-01 The Landscape of Aminoacyl-tRNA Synthetases Involved in Severe Acute Respiratory Syndrome Coronavirus 2 Infection (edit) 10.3389/FPHYS.2021.818297
2021-01-01 SARS-CoV-2 NSP1 C-terminal (residues 131–180) is an intrinsically disordered region in isolation (edit) 10.1016/J.CRVIRO.2021.100007
2021-01-01 SARS-CoV-2 viral proteins NSP1 and NSP13 inhibit interferon activation through distinct mechanisms (edit) 10.1371/JOURNAL.PONE.0253089
2021-01-01 Coronavirus Nsp1: Immune Response Suppression and Protein Expression Inhibition (edit) 10.3389/FMICB.2021.752214
2021-01-01 Overexpression of SARS-CoV-2 protein ORF6 dislocates RAE1 and NUP98 from the nuclear pore complex (edit) 10.1016/J.BBRC.2020.11.115
2021-01-01 The Functional Classification of ORF8 in SARS-CoV-2 Replication, Immune Evasion, and Viral Pathogenesis Inferred through Phylogenetic Profiling (edit) 10.1177/11769343211003079
2021-01-01 SARS-CoV-2 ORF8 Forms Intracellular Aggregates and Inhibits IFNγ-Induced Antiviral Gene Expression in Human Lung Epithelial Cells (edit) 10.3389/FIMMU.2021.679482
2021-01-01 Structure of SARS-CoV-2 ORF8, a rapidly evolving immune evasion protein (edit) 10.1073/PNAS.2021785118
2021-01-01 RIG-I-Like Receptor-Mediated Recognition of Viral Genomic RNA of Severe Acute Respiratory Syndrome Coronavirus-2 and Viral Escape From the Host Innate Immune Responses (edit) 10.3389/FIMMU.2021.700926
2021-01-01 SARS-CoV-2 Accessory Protein ORF7b Mediates Tumor Necrosis Factor-α-Induced Apoptosis in Cells (edit) 10.3389/FMICB.2021.654709
2021-01-01 Structural Analysis of SARS-CoV-2 ORF8 Protein: Pathogenic and Therapeutic Implications (edit) 10.3389/FGENE.2021.693227
2020-12-31 A novel virtual screening procedure identifies Pralatrexate as inhibitor of SARS-CoV-2 RdRp and it reduces viral replication in vitro (edit) 10.1371/JOURNAL.PCBI.1008489
2020-12-30 SARS-CoV-2 Nucleocapsid Protein Interacts with RIG-I and Represses RIG-Mediated IFN-β Production (edit) 10.3390/V13010047
2020-12-29 SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species (edit) 10.1080/22221751.2020.1870414
2020-12-29 Environmental Dependence of the Structure of the C-terminal Domain of the SARS-CoV-2 Envelope Protein (edit) 10.1101/2020.12.29.424646
2020-12-28 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling (edit) 10.1038/S41392-020-00438-7
2020-12-26 D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction (edit) 10.1016/J.CELREP.2020.108630
2020-12-26 Genomic diversity of SARS-CoV-2 can be accelerated by a mutation in the nsp14 gene (edit) 10.1101/2020.12.23.424231
2020-12-23 Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin (edit) 10.1055/S-0040-1721319
2020-12-23 Host Cell Proteases Drive Early or Late SARS-CoV-2 Penetration (edit) 10.1101/2020.12.22.423906
2020-12-21 Fatty Acid Synthase inhibition prevents palmitoylation of SARS-CoV2 Spike Protein and improves survival of mice infected with murine hepatitis virus (edit) 10.1101/2020.12.20.423603
2020-12-20 Implications of Spike-glycoprotein processing at S1/S2 by Furin, at S2’ by Furin and/or TMPRSS2 and shedding of ACE2: cell-to-cell fusion, cell entry and infectivity of SARS-CoV-2 (edit) 10.1101/2020.12.18.423106
2020-12-16 Subtle influence of ACE2 glycan processing on SARS-CoV-2 recognition (edit) 10.1016/J.JMB.2020.166762
2020-12-16 The S1 protein of SARS-CoV-2 crosses the blood–brain barrier in mice (edit) 10.1038/S41593-020-00771-8
2020-12-16 Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase (edit) 10.1016/J.BPJ.2020.11.2276
2020-12-11 High-Throughput Screening and Quantum Mechanics for Identifying Potent Inhibitors against Mac1 Domain of SARS-CoV-2 Nsp3 (edit) 10.1109/TCBB.2020.3037136
2020-12-11 Spike glycoprotein and host cell determinants of SARS-CoV-2 entry and cytopathic effects (edit) 10.1128/JVI.02304-20
2020-12-10 SARS-CoV-2 Nsp16 activation mechanism and a cryptic pocket with pan-coronavirus antiviral potential (edit) 10.1101/2020.12.10.420109
2020-12-10 The SARS-CoV-2 ORF10 is not essential in vitro or in vivo in humans (edit) 10.1371/JOURNAL.PPAT.1008959
2020-12-09 Real-Time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles (edit) 10.1016/J.CHOM.2020.11.001
2020-12-09 Ritonavir may inhibit exoribonuclease activity of nsp14 from the SARS-CoV-2 virus and potentiate the activity of chain terminating drugs (edit) 10.1016/J.IJBIOMAC.2020.12.038
2020-12-07 SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cells (edit) 10.1371/JOURNAL.PPAT.1009128
2020-12-07 Spike Protein of SARS-CoV-2 Activates Macrophages and Contributes to Induction of Acute Lung Inflammations in Mice (edit) 10.1101/2020.12.07.414706
2020-12-07 Structural characterization of Nonstructural protein 1 from SARS-CoV-2 (edit) 10.1016/J.ISCI.2020.101903
2020-12-07 Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles (edit) 10.1371/JOURNAL.PPAT.1009130
2020-12-04 Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM (edit) 10.1126/SCIADV.ABE5575
2020-12-03 1H, 13C, and 15N backbone chemical shift assignments of the C-terminal dimerization domain of SARS-CoV-2 nucleocapsid protein (edit) 10.1007/S12104-020-09995-Y
2020-12-02 Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein (edit) 10.1371/JOURNAL.PPAT.1009100
2020-12-02 Comparative Multiplexed Interactomics of SARS-CoV-2 and Homologous Coronavirus Nonstructural Proteins Identifies Unique and Shared Host-Cell Dependencies (edit) 10.1021/ACSINFECDIS.0C00500
2020-12-02 The viral protein NSP1 acts as a ribosome gatekeeper for shutting down host translation and fostering SARS-CoV-2 translation (edit) 10.1261/RNA.078121.120
2020-12-01 Flavonoids with inhibitory activity against SARS-CoV-2 3CLpro (edit) 10.1080/14756366.2020.1801672
2020-12-01 An aberrant STAT pathway is central to COVID-19 (edit) 10.1038/S41418-020-00633-7
2020-11-30 Characterization of SARS-CoV-2 N protein reveals multiple functional consequences of the C-terminal domain (edit) 10.1101/2020.11.30.404905
2020-11-27 Nucleocapsid protein of SARS-CoV-2 phase separates into RNA-rich polymerase-containing condensates (edit) 10.1038/S41467-020-19843-1
2020-11-27 Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid (edit) 10.1016/J.MOLCEL.2020.11.041
2020-11-24 Computational Investigation of Structural Dynamics of SARS-CoV-2 Methyltransferase-Stimulatory Factor Heterodimer nsp16/nsp10 Bound to the Cofactor SAM (edit) 10.3389/FMOLB.2020.590165
2020-11-24 Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking (edit) 10.1101/2020.11.24.393405
2020-11-24 Structure of nonstructural protein 1 from SARS-CoV-2 (edit) 10.1128/JVI.02019-20
2020-11-23 The SARS-CoV-2 Envelope and Membrane proteins modulate maturation and retention of the Spike protein, allowing assembly of virus-like particles (edit) 10.1074/JBC.RA120.016175
2020-11-23 1H,13C and 15N chemical shift assignments of the SUD domains of SARS-CoV-2 non-structural protein 3c: "the N-terminal domain-SUD-N" (edit) 10.1007/S12104-020-09987-Y
2020-11-20 Phosphoregulation of Phase Separation by the SARS-CoV-2 N Protein Suggests a Biophysical Basis for its Dual Functions (edit) 10.1016/J.MOLCEL.2020.11.025
2020-11-20 Dual ELISA using SARS-CoV-2 nucleocapsid protein produced in E. coli and CHO cells reveals epitope masking by N-glycosylation (edit) 10.1016/J.BBRC.2020.11.060
2020-11-20 1H, 13C, and 15N backbone and side chain chemical shift assignments of the SARS-CoV-2 non-structural protein 7 (edit) 10.1007/S12104-020-09985-0
2020-11-18 Room Temperature Structure of SARS-CoV-2 Nsp10/16 Methyltransferase in a Complex with Cap-0 and SAM Determined by Pink-Beam Serial Crystallography (edit) 10.2210/PDB7KOA/PDB
2020-11-18 SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography (edit) 10.1038/S41467-020-19619-7
2020-11-18 Sequential ER stress and inflammatory responses are induced by SARS-CoV-2 ORF3 through ERphagy (edit) 10.1101/2020.11.17.387902
2020-11-18 Loss of orf3b in the circulating SARS-CoV-2 strains (edit) 10.1080/22221751.2020.1852892
2020-11-18 Architecture of a SARS-CoV-2 mini replication and transcription complex (edit) 10.1038/S41467-020-19770-1
2020-11-17 A systemic and molecular study of subcellular localization of SARS-CoV-2 proteins (edit) 10.1038/S41392-020-00372-8
2020-11-17 SARS-CoV-2 nucleocapsid protein phase-separates with RNA and with human hnRNPs (edit) 10.15252/EMBJ.2020106478
2020-11-17 Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains (edit) 10.1016/J.CHOM.2020.11.004
2020-11-16 Analysis of SARS-CoV-2 spike glycosylation reveals shedding of a vaccine candidate (edit) 10.1101/2020.11.16.384594
2020-11-14 Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate State in Cap Synthesis (edit) 10.1016/J.CELL.2020.11.016
2020-11-13 Comparison of Binding Site of Remdesivir and Its Metabolites with NSP12-NSP7-NSP8, and NSP3 of SARS CoV-2 Virus and Alternative Potential Drugs for COVID-19 Treatment (edit) 10.1007/S10930-020-09942-9
2020-11-12 Bifurcations and mutation hot-spots in SARS-CoV-2 spike protein (edit) 10.1101/2020.11.11.378828
2020-11-12 ORF3a mediated-incomplete autophagy facilitates SARS-CoV-2 replication (edit) 10.1101/2020.11.12.380709
2020-11-11 Structure and drug binding of the SARS-CoV-2 envelope protein transmembrane domain in lipid bilayers (edit) 10.1038/S41594-020-00536-8
2020-11-11 Nsp1 of SARS-CoV-2 Stimulates Host Translation Termination (edit) 10.1101/2020.11.11.377739
2020-11-10 SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling (edit) 10.1073/PNAS.2016650117
2020-11-09 Towards Targeting the Disordered SARS-CoV-2 Nsp2 C-terminal Region: Partial Structure and Dampened Mobility Revealed by NMR Spectroscopy (edit) 10.1101/2020.11.09.374173
2020-11-08 RNA 2'-O-methylation modification and its implication in COVID-19 immunity (edit) 10.1038/S41420-020-00358-Z
2020-11-07 1H, 13C, and 15N backbone chemical shift assignments of coronavirus-2 non-structural protein Nsp10 (edit) 10.1007/S12104-020-09984-1
2020-11-06 The SARS-CoV-2 conserved macrodomain is a mono-ADP-ribosylhydrolase (edit) 10.1128/JVI.01969-20
2020-11-05 The N-terminal domain of spike glycoprotein mediates SARS-CoV-2 infection by associating with L-SIGN and DC-SIGN (edit) 10.1101/2020.11.05.369264
2020-11-05 Lysine 164 is critical for SARS-CoV-2 Nsp1 inhibition of host gene expression (edit) 10.1099/JGV.0.001513
2020-11-04 Coevolution, Dynamics and Allostery Conspire in Shaping Cooperative Binding and Signal Transmission of the SARS-CoV-2 Spike Protein with Human Angiotensin-Converting Enzyme 2 (edit) 10.3390/IJMS21218268
2020-11-04 Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs in vitro (edit) 10.1038/S41421-020-00222-5
2020-11-03 A Computational Approach for Identifying Potential Phytochemicals Against Non-structural Protein 1 (Nsp1) of SARS-CoV-2 (edit) 10.2174/1386207323999201103211106
2020-11-02 The SARS-CoV-2 spike protein: balancing stability and infectivity (edit) 10.1038/S41422-020-00430-4
2020-11-02 Structure of the SARS-CoV-2 Nsp1/5'-Untranslated Region Complex and Implications for Potential Therapeutic Targets, a Vaccine, and Virulence (edit) 10.1021/ACS.JPCLETT.0C02818
2020-11-01 An insight into SARS-CoV-2 Membrane protein interaction with Spike, Envelope, and Nucleocapsid proteins (edit) 10.1101/2020.10.30.363002
2020-10-30 Unfractionated heparin inhibits live wild-type SARS-CoV-2 cell infectivity at therapeutically relevant concentrations (edit) 10.1111/BPH.15304
2020-10-29 Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA (edit) 10.1016/J.MOLCEL.2020.10.034
2020-10-28 Identification of SARS-CoV-2 entry inhibitors among already approved drugs (edit) 10.1038/S41401-020-00556-6
2020-10-28 Binding mechanism and structural insights into the identified protein target of COVID-19 and importin-α with in-vitro effective drug ivermectin (edit) 10.1080/07391102.2020.1839564
2020-10-27 SARS-CoV-2 viroporin triggers the NLRP3 inflammatory pathway (edit) 10.1101/2020.10.27.357731
2020-10-27 SARS-CoV-2 membrane glycoprotein M antagonizes the MAVS-mediated innate antiviral response (edit) 10.1038/S41423-020-00571-X
2020-10-27 Remdesivir targets a structurally analogous region of the Ebola virus and SARS-CoV-2 polymerases (edit) 10.1073/PNAS.2012294117
2020-10-26 Characterization and structural prediction of the putative ORF10 protein in SARS-CoV-2 (edit) 10.1101/2020.10.26.355784
2020-10-23 SARS-CoV-2 Nucleocapsid protein attenuates stress granule formation and alters gene expression via direct interaction with host mRNAs (edit) 10.1101/2020.10.23.342113
2020-10-23 Transferrin receptor is another receptor for SARS-CoV-2 entry (edit) 10.1101/2020.10.23.350348
2020-10-22 The SARS-CoV-2 Spike Glycoprotein as a Drug and Vaccine Target: Structural Insights into Its Complexes with ACE2 and Antibodies (edit) 10.3390/CELLS9112343
2020-10-21 Structural Characterization of N‐Linked Glycans in the Receptor Binding Domain of the SARS‐CoV‐2 Spike Protein and their Interactions with Human Lectins (edit) 10.1002/ANGE.202011015
2020-10-20 Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity (edit) 10.1126/SCIENCE.ABD2985
2020-10-20 Neuropilin-1 is a host factor for SARS-CoV-2 infection (edit) 10.1126/SCIENCE.ABD3072
2020-10-20 Author Correction: SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation (edit) 10.1038/S41594-020-00533-X
2020-10-20 Accurate Diagnosis of COVID-19 by a Novel Immunogenic Secreted SARS-CoV-2 orf8 Protein (edit) 10.1128/MBIO.02431-20
2020-10-19 Site-specific N-glycosylation Characterization of Recombinant SARS-CoV-2 Spike Proteins (edit) 10.1074/MCP.RA120.002295
2020-10-16 Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design (edit) 10.1126/SCIADV.ABD4596
2020-10-16 Comprehensive Analysis of the Glycan Complement of SARS-CoV-2 Spike Proteins Using Signature Ions-Triggered Electron-Transfer/Higher-Energy Collisional Dissociation (EThcD) Mass Spectrometry (edit) 10.1021/ACS.ANALCHEM.0C03301
2020-10-16 The Integrin Binding Peptide, ATN-161, as a Novel Therapy for SARS-CoV-2 Infection (edit) 10.1016/J.JACBTS.2020.10.003
2020-10-16 Decline of Humoral Responses against SARS-CoV-2 Spike in Convalescent Individuals (edit) 10.1128/MBIO.02590-20
2020-10-15 A high throughput RNA displacement assay for screening SARS-CoV-2 nsp10-nsp16 complex towards developing therapeutics for COVID-19 (edit) 10.1101/2020.10.14.340034
2020-10-15 Unusual zwitterionic catalytic site of SARS-CoV-2 main protease revealed by neutron crystallography (edit) 10.1074/JBC.AC120.016154
2020-10-15 Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms (edit) 10.1126/SCIENCE.ABE9403
2020-10-15 The Strand-biased Transcription of SARS-CoV-2 and Unbalanced Inhibition by Remdesivir (edit) 10.1101/2020.10.15.325050
2020-10-14 The Architecture of Inactivated SARS-CoV-2 with Postfusion Spikes Revealed by Cryo-EM and Cryo-ET (edit) 10.1016/J.STR.2020.10.001
2020-10-14 The viral protein NSP1 acts as a ribosome gatekeeper for shutting down host translation and fostering SARS-CoV-2 translation (edit) 10.1101/2020.10.14.339515
2020-10-14 Discovery of COVID-19 Inhibitors Targeting the SARS-CoV-2 Nsp13 Helicase (edit) 10.1021/ACS.JPCLETT.0C02421
2020-10-13 Syncytia formation by SARS-CoV-2 infected cells (edit) 10.15252/EMBJ.2020106267
2020-10-12 Understanding the phase separation characteristics of nucleocapsid protein provides a new therapeutic opportunity against SARS-CoV-2 (edit) 10.1101/2020.10.09.332734
2020-10-12 Sequences in the cytoplasmic tail of SARS-CoV-2 spike facilitate syncytia formation (edit) 10.1101/2020.10.12.335562
2020-10-12 Mutations of SARS-CoV-2 nsp14 exhibit strong association with increased genome-wide mutation load (edit) 10.7717/PEERJ.10181
2020-10-11 The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood-brain barrier (edit) 10.1016/J.NBD.2020.105131
2020-10-10 Identification of novel mutations in the methyltransferase complex (Nsp10-Nsp16) of SARS-CoV-2 (edit) 10.1016/J.BBREP.2020.100833
2020-10-09 Inhibition of translation and immune responses by the virulence factor Nsp1 of SARS-CoV-2 (edit) 10.1038/S41392-020-00350-0
2020-10-08 SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses (edit) 10.1016/J.CELL.2020.10.004
2020-10-08 Preferential recognition and antagonism of SARS-CoV-2 spike glycoprotein binding to 3- O -sulfated heparan sulfate (edit) 10.1101/2020.10.08.331751
2020-10-07 Mass spectrometric based detection of protein nucleotidylation in the RNA polymerase of SARS-CoV-2 (edit) 10.1101/2020.10.07.330324
2020-10-07 Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters (edit) 10.1038/S41564-020-00802-X
2020-10-07 NSP 11 of SARS-CoV-2 is an Intrinsically Disordered Protein (edit) 10.1101/2020.10.07.330068
2020-10-06 Crystal Structure of Non-Structural Protein 10 from Severe Acute Respiratory Syndrome Coronavirus-2 (edit) 10.3390/IJMS21197375
2020-10-06 Main protease of SARS-CoV-2 serves as a bifunctional molecule in restricting type I interferon antiviral signaling (edit) 10.1038/S41392-020-00332-2
2020-10-06 Autoproteolytic Products of the SARS-CoV-2 Nucleocapsid Protein are Primed for Antibody Evasion and Virus Proliferation (edit) 10.1101/2020.10.06.328112
2020-10-03 High-resolution structure and biophysical characterization of the nucleocapsid phosphoprotein dimerization domain from the Covid-19 severe acute respiratory syndrome coronavirus 2 (edit) 10.1016/J.BBRC.2020.09.131
2020-10-01 Structural insight into the recognition of S-adenosyl-L-homocysteine and sinefungin in SARS-CoV-2 Nsp16/Nsp10 RNA cap 2'-O-Methyltransferase (edit) 10.1016/J.CSBJ.2020.09.032
2020-10-01 Mechanistic insights of host cell fusion of SARS-CoV-1 and SARS-CoV-2 from atomic resolution structure and membrane dynamics (edit) 10.1016/J.BPC.2020.106438
2020-10-01 Targeting SARS-CoV2 Spike Protein Receptor Binding Domain by Therapeutic Antibodies (edit) 10.1016/J.BIOPHA.2020.110559
2020-10-01 SARS-CoV-2 Spike protein co-opts VEGF-A/Neuropilin-1 receptor signaling to induce analgesia (edit) 10.1097/J.PAIN.0000000000002097
2020-10-01 Lost in deletion: The enigmatic ORF8 protein of SARS-CoV-2 (edit) 10.1016/J.BBRC.2020.10.045
2020-09-30 The furin cleavage site of SARS-CoV-2 spike protein is a key determinant for transmission due to enhanced replication in airway cells (edit) 10.1101/2020.09.30.318311
2020-09-29 High-resolution structures of the SARS-CoV-2 2'-O-methyltransferase reveal strategies for structure-based inhibitor design (edit) 10.1126/SCISIGNAL.ABE1202
2020-09-28 Discovery of Drug-Like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3 (edit) 10.1177/2472555220960428
2020-09-24 Evaluation of the potency of FDA-approved drugs on wild type and mutant SARS-CoV-2 helicase (Nsp13) (edit) 10.1016/J.IJBIOMAC.2020.09.138
2020-09-23 Crystal Structure of NSP15 Endoribonuclease from SARS CoV-2 in the Complex with Uridine-3',5'-Diphosphate (edit) 10.2210/PDB7K1O/PDB
2020-09-23 Beyond Shielding: The Roles of Glycans in the SARS-CoV-2 Spike Protein (edit) 10.1021/ACSCENTSCI.0C01056
2020-09-23 The SARS-COV-2 Spike Protein Binds Sialic Acids and Enables Rapid Detection in a Lateral Flow Point of Care Diagnostic Device (edit) 10.1021/ACSCENTSCI.0C00855
2020-09-23 Insights into the biased activity of dextromethorphan and haloperidol towards SARS-CoV-2 NSP6: in silico binding mechanistic analysis (edit) 10.1007/S00109-020-01980-1
2020-09-21 Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein (edit) 10.1126/SCIENCE.ABD3255
2020-09-19 Evasion of Type I Interferon by SARS-CoV-2 (edit) 10.1016/J.CELREP.2020.108234
2020-09-18 Structural, biophysical and biochemical elucidation of the SARS-CoV-2 nonstructural protein 3 macro domain (edit) 10.1021/ACSINFECDIS.0C00441
2020-09-18 Cholesterol 25-Hydroxylase inhibits SARS-CoV-2 and coronaviruses by depleting membrane cholesterol (edit) 10.15252/EMBJ.2020106057
2020-09-18 KIM-1/TIM-1 is a Receptor for SARS-CoV-2 in Lung and Kidney (edit) 10.1101/2020.09.16.20190694
2020-09-18 SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism (edit) 10.1101/2020.09.18.302901
2020-09-17 Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion (edit) 10.1038/S41586-020-2772-0
2020-09-16 Characterisation of protease activity during SARS-CoV-2 infection identifies novel viral cleavage sites and cellular targets for drug repurposing (edit) 10.1101/2020.09.16.297945
2020-09-16 SARS-CoV-2 protein Nsp1 alters actomyosin cytoskeleton and phenocopies arrhythmogenic cardiomyopathy-related PKP2 mutant (edit) 10.1101/2020.09.14.296178
2020-09-16 Targeting SARS-CoV-2 Nsp12/Nsp8 interaction interface with approved and investigational drugs: an in silico structure-based approach (edit) 10.1080/07391102.2020.1819882
2020-09-16 The enzymatic activity of the nsp14 exoribonuclease is critical for replication of MERS-CoV and SARS-CoV-2 (edit) 10.1128/JVI.01246-20
2020-09-15 SARS-CoV-2 N protein antagonizes type I interferon signaling by suppressing phosphorylation and nuclear translocation of STAT1 and STAT2 (edit) 10.1038/S41421-020-00208-3
2020-09-14 SARS CoV-2 nucleocapsid protein forms condensates with viral genomic RNA (edit) 10.1101/2020.09.14.295824
2020-09-14 SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2 (edit) 10.1016/J.CELL.2020.09.033
2020-09-14 Genes with 5' terminal oligopyrimidine tracts preferentially escape global suppression of translation by the SARS-CoV-2 NSP1 protein (edit) 10.1101/2020.09.13.295493
2020-09-13 Real-time conformational dynamics of SARS-CoV-2 spikes on virus particles (edit) 10.1101/2020.09.10.286948
2020-09-11 A COVID-19 antibody curbs SARS-CoV-2 nucleocapsid protein-induced complement hyper-activation (edit) 10.1101/2020.09.10.292318
2020-09-11 Structural characterization of the N-linked glycans in the receptor binding domain of the SARS-CoV-2 spike protein and their interactions with human lectins using NMR spectroscopy (edit) 10.1002/ANIE.202011015
2020-09-11 SARS-CoV-2 NSP1 C-terminal region (residues 130-180) is an intrinsically disordered region (edit) 10.1101/2020.09.10.290932
2020-09-09 Repurposing of FDA-Approved Toremifene to Treat COVID-19 by blocking the spike glycoprotein and NSP14 of SARS-CoV-2 (edit) 10.1021/ACS.JPROTEOME.0C00397
2020-09-09 Interaction network of SARS-CoV-2 with host receptome through spike protein (edit) 10.1101/2020.09.09.287508
2020-09-09 SARS-CoV-2 envelope protein topology in eukaryotic membranes (edit) 10.1098/RSOB.200209
2020-09-09 SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation (edit) 10.1038/S41594-020-0511-8
2020-09-08 In-silico screening of plant-derived antivirals against main protease, 3CLpro and endoribonuclease, NSP15 proteins of SARS-CoV-2 (edit) 10.1080/07391102.2020.1808077
2020-09-08 Liquid-liquid phase separation by SARS-CoV-2 nucleocapsid protein and RNA (edit) 10.1038/S41422-020-00408-2
2020-09-07 Potential Treatment of Chinese and Western Medicine Targeting Nsp14 of SARS-CoV-2 (edit) 10.1016/J.JPHA.2020.08.002
2020-09-06 Molecular Architecture of the SARS-CoV-2 Virus (edit) 10.1016/J.CELL.2020.09.018
2020-09-04 Identification of promising antiviral drug candidates against non-structural protein 15 (NSP15) from SARS-CoV-2: an in silico assisted drug-repurposing study (edit) 10.1080/07391102.2020.1814870
2020-09-04 Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease (edit) 10.1038/S41467-020-18233-X
2020-09-04 Evaluation of SARS-CoV-2 3C-like protease inhibitors using self-assembled monolayer desorption ionization mass spectrometry (edit) 10.1016/J.ANTIVIRAL.2020.104924
2020-09-04 Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-Throughput Screening (edit) 10.1021/ACSPTSCI.0C00108
2020-09-04 SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19 (edit) 10.1186/S13045-020-00954-7
2020-09-04 Multimerization- and glycosylation-dependent receptor binding of SARS-CoV-2 spike proteins (edit) 10.1101/2020.09.04.282558
2020-09-04 SARS-CoV-2 ORF3b Is a Potent Interferon Antagonist Whose Activity Is Increased by a Naturally Occurring Elongation Variant (edit) 10.1016/J.CELREP.2020.108185
2020-09-03 Identification of phytochemicals as potential therapeutic agents that binds to Nsp15 protein target of coronavirus (SARS-CoV-2) that are capable of inhibiting virus replication (edit) 10.1016/J.PHYMED.2020.153317
2020-09-03 Improved binding of SARS-CoV-2 Envelope protein to tight junction-associated PALS1 could play a key role in COVID-19 pathogenesis (edit) 10.1016/J.MICINF.2020.08.006
2020-09-02 Crystal structure of SARS-CoV-2 papain-like protease (edit) 10.1016/J.APSB.2020.08.014
2020-09-02 Direct activation of the alternative complement pathway by SARS-CoV-2 spike proteins is blocked by factor D inhibition (edit) 10.1182/BLOOD.2020008248
2020-09-01 Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19 (edit) 10.1038/S41401-020-0485-4
2020-08-31 Emerging of a SARS-CoV-2 viral strain with a deletion in nsp1 (edit) 10.1186/S12967-020-02507-5
2020-08-30 Mass Spectrometry Analysis of Newly Emerging Coronavirus HCoV-19 Spike Protein and Human ACE2 Reveals Camouflaging Glycans and Unique Post-Translational Modifications (edit) 10.1016/J.ENG.2020.07.014
2020-08-29 The SARS-CoV-2 ORF10 is not essential in vitro or in vivo in humans (edit) 10.1101/2020.08.29.257360
2020-08-28 In silico structure modelling of SARS-CoV-2 Nsp13 helicase and Nsp14 and repurposing of FDA approved antiviral drugs as dual inhibitors (edit) 10.1016/J.GENREP.2020.100860
2020-08-27 SARS-CoV-2 Nucleocapsid protein is decorated with multiple N- and O-glycans (edit) 10.1101/2020.08.26.269043
2020-08-27 Structure of SARS-CoV-2 ORF8, a rapidly evolving coronavirus protein implicated in immune evasion (edit) 10.1101/2020.08.27.270637
2020-08-26 Room Temperature Structure of SARS-CoV-2 Nsp10/Nsp16 Methyltransferase in a Complex with m7GpppA Cap-0 and SAM Determined by Fixed-Target Serial Crystallography (edit) 10.2210/PDB7JPE/PDB
2020-08-26 Room Temperature Crystal Structure of Nsp10/Nsp16 from SARS-CoV-2 with Substrates and Products of 2'-O-methylation of the Cap-1 (edit) 10.2210/PDB7JIB/PDB
2020-08-26 Room Temperature Structure of SARS-CoV-2 Nsp10/Nsp16 Methyltransferase in a Complex with 2'-O-methylated m7GpppA Cap-1 and SAH Determined by Fixed-Target Serial Crystallography (edit) 10.2210/PDB7JHE/PDB
2020-08-26 Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2 (edit) 10.15252/EMBJ.2020106275
2020-08-26 SARS-CoV-2 Spike 1 Protein Controls Natural Killer Cell Activation via the HLA-E/NKG2A Pathway (edit) 10.3390/CELLS9091975
2020-08-26 Crystal Structure of SARS-CoV-2 NSP7-NSP8 complex (edit) 10.2210/PDB7JLT/PDB
2020-08-25 The S1/S2 boundary of SARS-CoV-2 spike protein modulates cell entry pathways and transmission (edit) 10.1101/2020.08.25.266775
2020-08-24 In silico validation of coumarin derivatives as potential inhibitors against Main Protease, NSP10/NSP16-Methyltransferase, Phosphatase and Endoribonuclease of SARS CoV-2 (edit) 10.1080/07391102.2020.1808075
2020-08-24 The SARS-CoV-2 Envelope and Membrane proteins modulate maturation and retention of the Spike protein, allowing optimal formation of VLPs in presence of Nucleoprotein (edit) 10.1101/2020.08.24.260901
2020-08-24 Dynamics of the N-terminal domain of SARS-CoV-2 nucleocapsid protein drives dsRNA melting in a counterintuitive tweezer-like mechanism (edit) 10.1101/2020.08.24.264465
2020-08-24 Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor (edit) 10.1016/J.CHOM.2020.08.004
2020-08-24 SARS-CoV-2 Spike protein co-opts VEGF-A/Neuropilin-1 receptor signaling to induce analgesia (edit) 10.1101/2020.07.17.209288
2020-08-24 Pathogenicity, immunogenicity, and protective ability of an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction of the spike protein (edit) 10.1101/2020.08.24.264192
2020-08-21 Dynamic competition between SARS-CoV-2 NSP1 and mRNA on the human ribosome inhibits translation initiation (edit) 10.1101/2020.08.20.259770
2020-08-20 Structural basis for the multimerization of nonstructural protein nsp9 from SARS-CoV-2 (edit) 10.1186/S43556-020-00005-0
2020-08-20 SARS-CoV-2 ORF8 and SARS-CoV ORF8ab: Genomic Divergence and Functional Convergence (edit) 10.3390/PATHOGENS9090677
2020-08-19 SARS-CoV-2 ORF9c Is a Membrane-Associated Protein that Suppresses Antiviral Responses in Cells (edit) 10.1101/2020.08.18.256776
2020-08-18 In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges (edit) 10.1126/SCIENCE.ABD5223
2020-08-18 Vitamin B12 may inhibit RNA-dependent-RNA polymerase activity of nsp12 from the SARS-CoV-2 virus (edit) 10.1002/IUB.2359
2020-08-17 Structures and distributions of SARS-CoV-2 spike proteins on intact virions (edit) 10.1038/S41586-020-2665-2
2020-08-17 ORF8 and ORF3b antibodies are accurate serological markers of early and late SARS-CoV-2 infection (edit) 10.1038/S41590-020-0773-7
2020-08-17 SARS-CoV-2 ORF9b Antagonizes Type I and III Interferons by Targeting Multiple Components of RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING Signaling Pathways (edit) 10.1101/2020.08.16.252973
2020-08-14 Methylation of RNA Cap in SARS-CoV-2 captured by serial crystallography (edit) 10.1101/2020.08.14.251421
2020-08-14 The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid phosphorylation and inhibits viral infection in vitro (edit) 10.1101/2020.08.14.251207
2020-08-14 Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion (edit) 10.1101/2020.08.13.243303
2020-08-14 1H, 13C, and 15N backbone chemical shift assignments of the apo and the ADP-ribose bound forms of the macrodomain of SARS-CoV-2 non-structural protein 3b (edit) 10.1007/S12104-020-09973-4
2020-08-13 Characterisation of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification (edit) 10.1101/2020.08.13.248211
2020-08-13 The use of knowledge management tools in viroinformatics. Example study of a highly conserved sequence motif in Nsp3 of SARS-CoV-2 as a therapeutic target (edit) 10.1016/J.COMPBIOMED.2020.103963
2020-08-13 Maraviroc inhibits SARS-CoV-2 multiplication and s-protein mediated cell fusion in cell culture (edit) 10.1101/2020.08.12.246389
2020-08-12 Structural insight into the role of novel SARS-CoV-2 E protein: A potential target for vaccine development and other therapeutic strategies (edit) 10.1371/JOURNAL.PONE.0237300
2020-08-12 Suppression of MDA5-mediated antiviral immune responses by NSP8 of SARS-CoV-2 (edit) 10.1101/2020.08.12.247767
2020-08-11 Cryo-EM Structures of the SARS-CoV-2 Endoribonuclease Nsp15 (edit) 10.1101/2020.08.11.244863
2020-08-11 Growth Factor Receptor Signaling Inhibition Prevents SARS-CoV-2 Replication (edit) 10.1016/J.MOLCEL.2020.08.006
2020-08-11 In Silico Identification of Potential Inhibitors of ADP-Ribose Phosphatase of SARS-CoV-2 nsP3 by Combining E-Pharmacophore- and Receptor-Based Virtual Screening of Database (edit) 10.1002/SLCT.202001419
2020-08-11 Mutational spectra of SARS-CoV-2 orf1ab polyprotein and signature mutations in the United States of America (edit) 10.1002/JMV.26417
2020-08-10 Repurposing of SARS-CoV nucleocapsid protein specific nuclease resistant RNA aptamer for therapeutics against SARS-CoV-2 (edit) 10.1016/J.MEEGID.2020.104497
2020-08-10 DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist (edit) 10.1101/2020.08.09.242917
2020-08-10 Discovery of COVID-19 Inhibitors Targeting the SARS-CoV2 Nsp13 Helicase (edit) 10.1101/2020.08.09.243246
2020-08-09 Mass Spectrometric detection of SARS-CoV-2 virus in scrapings of the epithelium of the nasopharynx of infected patients via Nucleocapsid N protein (edit) 10.1021/ACS.JPROTEOME.0C00412
2020-08-07 Epigallocatechin gallate and theaflavin gallate interaction in SARS-CoV-2 spike-protein central channel with reference to the hydroxychloroquine interaction: Bioinformatics and molecular docking study (edit) 10.1002/DDR.21730
2020-08-06 Structural characterization of the C-terminal domain of SARS-CoV-2 nucleocapsid protein (edit) 10.1186/S43556-020-00001-4
2020-08-06 Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors (edit) 10.1101/2020.08.06.240192
2020-08-05 Intra- and intermolecular atomic-scale interactions in the receptor binding domain of SARS-CoV-2 spike protein: implication for ACE2 receptor binding (edit) 10.1039/D0CP03145C
2020-08-05 Structure of Furin Protease Binding to SARS-CoV-2 Spike Glycoprotein and Implications for Potential Targets and Virulence (edit) 10.1021/ACS.JPCLETT.0C01698
2020-08-04 SARS-CoV-2 nucleocapsid and Nsp3 binding: an in silico study (edit) 10.1007/S00203-020-01998-6
2020-08-04 Deciphering the protein motion of S1 subunit in SARS-CoV-2 spike glycoprotein through integrated computational methods (edit) 10.1080/07391102.2020.1802338
2020-08-04 Role of key point Mutations in Receptor Binding Domain of SARS-CoV-2 Spike Glycoprotein (edit) 10.2174/1871526520666200804161650
2020-08-04 Enhanced Binding of SARS-CoV-2 Spike Protein to Receptor by Distal Polybasic Cleavage Sites (edit) 10.1021/ACSNANO.0C04798
2020-08-03 Identification of promising drug candidates against NSP16 of SARS-CoV-2 through computational drug repurposing study (edit) 10.1080/07391102.2020.1802349
2020-08-03 Structure of SARS-CoV-2 2′-O-methyltransferase heterodimer with RNA Cap analog and sulfates bound reveals new strategies for structure-based inhibitor design (edit) 10.1101/2020.08.03.234716
2020-08-03 SARS-CoV-2 ORF6 disrupts nucleocytoplasmic transport through interactions with Rae1 and Nup98 (edit) 10.1101/2020.08.03.234559
2020-08-02 A Systemic and Molecular Study of Subcellular Localization of SARS-CoV-2 Proteins (edit) 10.1101/2020.08.02.233023
2020-08-01 In Silico Screening of Potential Spike Glycoprotein Inhibitors of SARS-CoV-2 with Drug Repurposing Strategy (edit) 10.1007/S11655-020-3427-6
2020-08-01 Genomic variance of Open Reading Frames (ORFs) and Spike protein in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (edit) 10.1097/JCMA.0000000000000387
2020-07-31 Antibody response against SARS-CoV-2 spike protein and nucleoprotein evaluated by 4 automated immunoassays and 3 ELISAs (edit) 10.1016/J.CMI.2020.07.038
2020-07-31 The SARS-CoV-2 Nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein (edit) 10.1101/2020.07.30.228023
2020-07-31 A thermostable, closed SARS-CoV-2 spike protein trimer (edit) 10.1038/S41594-020-0478-5
2020-07-31 Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase (edit) 10.1101/2020.07.31.231274
2020-07-30 Substrate specificity of SARS-CoV-2 nsp10-nsp16 methyltransferase (edit) 10.1101/2020.07.30.228478
2020-07-30 Transcriptome & viral growth analysis of SARS-CoV-2-infected Vero CCL-81 cells (edit) 10.4103/IJMR.IJMR_2257_20
2020-07-30 A dynamic regulatory interface on SARS-CoV-2 RNA polymerase (edit) 10.1101/2020.07.30.229187
2020-07-29 Crystal structure of SARS-CoV-2 nsp10/nsp16 2'-O-methylase and its implication on antiviral drug design (edit) 10.1038/S41392-020-00241-4
2020-07-29 Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity (edit) 10.1038/S41586-020-2601-5
2020-07-29 SARS-CoV-2 Orf9b suppresses type I interferon responses by targeting TOM70 (edit) 10.1038/S41423-020-0514-8
2020-07-28 Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein (edit) 10.1186/S13073-020-00763-0
2020-07-28 Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex (edit) 10.1016/J.CELL.2020.07.033
2020-07-27 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Membrane (M) Protein Inhibits Type I and III Interferon Production by Targeting RIG-I/MDA-5 Signaling (edit) 10.1101/2020.07.26.222026
2020-07-26 No evidence for basigin/CD147 as a direct SARS-CoV-2 spike binding receptor (edit) 10.1101/2020.07.25.221036
2020-07-24 Structural basis of RNA cap modification by SARS-CoV-2 (edit) 10.1038/S41467-020-17496-8
2020-07-24 Identification, Mapping and Relative Quantitation of SARS-CoV-2 Spike Glycopeptides by Mass-Retention Time Fingerprinting (edit) 10.1101/2020.07.24.217562
2020-07-24 Computational drug repurposing for the identification of SARS-CoV-2 main protease inhibitors (edit) 10.1080/07391102.2020.1796805
2020-07-24 SARS-CoV-2 ORF8 and SARS-CoV ORF8ab: Genomic Divergence and Functional Convergence (edit) 10.20944/PREPRINTS202007.0587.V1
2020-07-23 TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells (edit) 10.26508/LSA.202000786
2020-07-22 Linear B-cell epitopes in the spike and nucleocapsid proteins as markers of SARS-CoV-2 exposure and disease severity (edit) 10.1016/J.EBIOM.2020.102911
2020-07-22 Controlling the SARS-CoV-2 spike glycoprotein conformation (edit) 10.1038/S41594-020-0479-4
2020-07-21 Distinct conformational states of SARS-CoV-2 spike protein (edit) 10.1126/SCIENCE.ABD4251
2020-07-18 Structural basis for the inhibition of the papain-like protease of SARS-CoV-2 by small molecules (edit) 10.1101/2020.07.17.208959
2020-07-17 Crystal structures of SARS-CoV-2 ADP-ribose phosphatase: from the apo form to ligand complexes (edit) 10.1107/S2052252520009653
2020-07-17 Cryo-EM analysis of the post-fusion structure of the SARS-CoV spike glycoprotein (edit) 10.1038/S41467-020-17371-6
2020-07-17 Natural Polymorphisms Are Present in the Furin Cleavage Site of the SARS-CoV-2 Spike Glycoprotein (edit) 10.3389/FGENE.2020.00783
2020-07-17 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2 (edit) 10.1126/SCIENCE.ABC8665
2020-07-15 Bivalent binding of a fully human IgG to the SARS-CoV-2 spike proteins reveals mechanisms of potent neutralization (edit) 10.1101/2020.07.14.203414
2020-07-15 A putative new SARS-CoV protein, 3c, encoded in an ORF overlapping ORF3a (edit) 10.1099/JGV.0.001469
2020-07-13 Cold sensitivity of the SARS-CoV-2 spike ectodomain (edit) 10.1101/2020.07.12.199588
2020-07-13 Identification of potential drugs against SARS-CoV-2 non-structural protein 1 (nsp1) (edit) 10.1080/07391102.2020.1792992
2020-07-13 Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex (edit) 10.1101/2020.07.08.194084
2020-07-12 Architecture and self-assembly of the SARS-CoV-2 nucleocapsid protein (edit) 10.1002/PRO.3909
2020-07-10 Stabilizing the Closed SARS-CoV-2 Spike Trimer (edit) 10.1101/2020.07.10.197814
2020-07-09 Molecular architecture of the SARS-CoV-2 virus (edit) 10.1101/2020.07.08.192104
2020-07-09 Characterization of heparin and severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) spike glycoprotein binding interactions (edit) 10.1016/J.ANTIVIRAL.2020.104873
2020-07-09 Decline of humoral responses against SARS-CoV-2 Spike in convalescent individuals (edit) 10.1101/2020.07.09.194639
2020-07-08 Room Temperature Structure of SARS-CoV-2 NSP10/NSP16 Methyltransferase in a Complex with SAM Determined by Fixed-Target Serial Crystallography (edit) 10.2210/PDB6XKM/PDB
2020-07-07 SARS-CoV-2 Nsp1 binds ribosomal mRNA channel to inhibit translation (edit) 10.1101/2020.07.07.191676
2020-07-06 Discovery of Drug-like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3 (edit) 10.1101/2020.07.06.190413
2020-07-06 N and O glycosylation of the SARS-CoV-2 spike protein (edit) 10.1101/2020.07.05.187344
2020-07-04 A pH-dependent switch mediates conformational masking of SARS-CoV-2 spike (edit) 10.1101/2020.07.04.187989
2020-07-03 Tracking changes in SARS-CoV-2 Spike: evidence that D614G increases infectivity of the COVID-19 virus (edit) 10.1016/J.CELL.2020.06.043
2020-07-02 6-Thioguanine blocks SARS-CoV-2 replication by inhibition of PLpro protease activities (edit) 10.1101/2020.07.01.183020
2020-07-01 The 1.5 A Crystal Structure of the Co-factor Complex of NSP7 and the C-terminal Domain of NSP8 from SARS CoV-2 (edit) 10.2210/PDB6XIP/PDB
2020-06-30 Glycans on the SARS-CoV-2 Spike Control the Receptor Binding Domain Conformation (edit) 10.1101/2020.06.26.173765
2020-06-30 Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM (edit) 10.1101/2020.06.30.177097
2020-06-29 Phosphorylation modulates liquid-liquid phase separation of the SARS-CoV-2 N protein (edit) 10.1101/2020.06.28.176248
2020-06-29 A sequence alignment and analysis of SARS-CoV-2 spike glycoprotein (edit)
2020-06-29 SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damage and constitutes an antiviral target (edit) 10.1101/2020.06.27.174953
2020-06-29 Proteins Nsp12 and 13 of SARS-CoV-2 Have Mitochondrial Recognition Signal: A Connection with Cellular Mitochondrial Dysfunction and Disease Manifestation (edit) 10.20944/PREPRINTS202006.0352.V1
2020-06-28 The Global Phosphorylation Landscape of SARS-CoV-2 Infection (edit) 10.1016/J.CELL.2020.06.034
2020-06-27 Structures, conformations and distributions of SARS-CoV-2 spike protein trimers on intact virions (edit) 10.1101/2020.06.27.174979
2020-06-26 Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2 (edit) 10.1101/2020.06.26.173872
2020-06-26 In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges (edit) 10.1101/2020.06.26.173476
2020-06-24 Structural plasticity of SARS-CoV-2 3CL Mpro active site cavity revealed by room temperature X-ray crystallography (edit) 10.1038/S41467-020-16954-7
2020-06-24 Molecular Basis for ADP-ribose Binding to the Mac1 Domain of SARS-CoV-2 Nsp3 (edit) 10.1021/ACS.BIOCHEM.0C00309
2020-06-24 Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 By Disrupting The Spike-ACE2 interaction (edit) 10.1101/2020.06.24.169334
2020-06-24 SARS-CoV-2 and SARS-CoV: Virtual Screening of Potential inhibitors targeting RNA-dependent RNA polymerase activity (NSP12) (edit) 10.1002/JMV.26222
2020-06-23 Targeting SARS-COV-2 non-structural protein 16: a virtual drug repurposing study (edit) 10.1080/07391102.2020.1779133
2020-06-23 The ORF6, ORF8 and nucleocapsid proteins of SARS-CoV-2 inhibit type I interferon signaling pathway (edit) 10.1016/J.VIRUSRES.2020.198074
2020-06-23 CD209L/L-SIGN and CD209/DC-SIGN act as receptors for SARS-CoV-2 and are differentially expressed in lung and kidney epithelial and endothelial cells (edit) 10.1101/2020.06.22.165803
2020-06-23 SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography (edit) 10.1101/2020.06.23.167064
2020-06-23 Biochemical evidence of furin specificity and potential for phospho-regulation at Spike protein S1/S2 cleavage site in SARS-CoV2 but not in SARS-CoV1 or MERS-CoV (edit) 10.1101/2020.06.23.166900
2020-06-23 Identification of multiple large deletions in ORF7a resulting in in-frame gene fusions in clinical SARS-CoV-2 isolates (edit) 10.1016/J.JCV.2020.104523
2020-06-22 Structure-based virtual screening and molecular dynamics simulation of SARS-CoV-2 Guanine-N7 methyltransferase (nsp14) for identifying antiviral inhibitors against COVID-19 (edit) 10.1080/07391102.2020.1778535
2020-06-20 SARS-CoV-2 E protein is a potential ion channel that can be inhibited by Gliclazide and Memantine (edit) 10.1016/J.BBRC.2020.05.206
2020-06-19 Nucleocapsid protein of SARS-CoV-2 phase separates into RNA-rich polymerase-containing condensates (edit) 10.1101/2020.06.18.160648
2020-06-19 Mechanism and inhibition of SARS-CoV-2 PLpro (edit) 10.1101/2020.06.18.160614
2020-06-18 Identification of bioactive compounds from Glycyrrhiza glabra as possible inhibitor of SARS-CoV-2 spike glycoprotein and non-structural protein-15: a pharmacoinformatics study (edit) 10.1080/07391102.2020.1779132
2020-06-18 The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA (edit) 10.1101/2020.06.17.158121
2020-06-18 The ORF3a protein of SARS-CoV-2 induces apoptosis in cells (edit) 10.1038/S41423-020-0485-9
2020-06-18 Cryo-EM structure of the SARS-CoV-2 3a ion channel in lipid nanodiscs (edit) 10.1101/2020.06.17.156554
2020-06-18 Unexpected free fatty acid binding pocket in the cryo-EM structure of SARS-CoV-2 spike protein (edit) 10.1101/2020.06.18.158584
2020-06-17 Crystal structure of 2019-nCoV nsp16-nsp10 complex (edit) 10.2210/PDB7BQ7/PDB
2020-06-17 Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis (edit) 10.1101/2020.06.14.150607
2020-06-17 A thermostable, closed, SARS-CoV-2 spike protein trimer (edit) 10.1101/2020.06.15.152835
2020-06-17 X-ray Crystallographic Structure of Orf9b from SARS-CoV-2 (edit) 10.2210/PDB6Z4U/PDB
2020-06-16 Proteasome activator PA28γ-dependent degradation of coronavirus disease (COVID-19) nucleocapsid protein (edit) 10.1016/J.BBRC.2020.06.058
2020-06-15 A Putative Role of de-Mono-ADP-Ribosylation of STAT1 by the SARS-CoV-2 Nsp3 Protein in the Cytokine Storm Syndrome of COVID-19 (edit) 10.3390/V12060646
2020-06-12 SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists (edit) 10.1080/22221751.2020.1780953
2020-06-12 Specific viral RNA drives the SARS CoV-2 nucleocapsid to phase separate (edit) 10.1101/2020.06.11.147199
2020-06-12 The role of furin cleavage site in SARS-CoV-2 spike protein-mediated membrane fusion in the presence or absence of trypsin (edit) 10.1038/S41392-020-0184-0
2020-06-12 The D614G mutation in the SARS-CoV-2 spike protein reduces S1 shedding and increases infectivity (edit) 10.1101/2020.06.12.148726
2020-06-11 Shielding and Beyond: The Roles of Glycans in SARS-CoV-2 Spike Protein (edit) 10.1101/2020.06.11.146522
2020-06-11 Structural analysis of the putative SARS-CoV-2 primase complex (edit) 10.1016/J.JSB.2020.107548
2020-06-10 SARS-CoV-2 nucleocapsid protein undergoes liquid-liquid phase separation stimulated by RNA and partitions into phases of human ribonucleoproteins (edit) 10.1101/2020.06.09.141101
2020-06-10 Identification of 22 N-glycosites on spike glycoprotein of SARS-CoV-2 and accessible surface glycopeptide motifs: implications for vaccination and antibody therapeutics (edit) 10.1093/GLYCOB/CWAA052
2020-06-10 The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S Protein-Mediated Fusion in a Cell Fusion Assay System and Viral Infection In Vitro in a Cell-Type-Dependent Manner (edit) 10.3390/V12060629
2020-06-10 A Rare Deletion in SARS-CoV-2 ORF6 Dramatically Alters the Predicted Three-Dimensional Structure of the Resultant Protein (edit) 10.1101/2020.06.09.134460
2020-06-09 Crystal Structure of the SARS-CoV-2 Non-structural Protein 9, Nsp9 (edit) 10.1016/J.ISCI.2020.101258
2020-06-08 Antibody signature induced by SARS-CoV-2 spike protein immunogens in rabbits (edit) 10.1126/SCITRANSLMED.ABC3539
2020-06-07 Neuropilin-1 facilitates SARS-CoV-2 cell entry and provides a possible pathway into the central nervous system (edit) 10.1101/2020.06.07.137802
2020-06-05 SARS-CoV-2 proteases cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species and the search for reservoir hosts (edit) 10.1101/2020.06.05.135699
2020-06-05 Neuropilin-1 is a host factor for SARS-CoV-2 infection (edit) 10.1101/2020.06.05.134114
2020-06-05 Identification of nsp1 gene as the target of SARS-CoV-2 real-time RT-PCR using nanopore whole genome sequencing (edit) 10.1002/JMV.26140
2020-06-05 Immune evasion via SARS-CoV-2 ORF8 protein? (edit) 10.1038/S41577-020-0360-Z
2020-06-04 SARS-Coronavirus-2 Nsp13 Possesses NTPase and RNA Helicase Activities That Can Be Inhibited by Bismuth Salts (edit) 10.1007/S12250-020-00242-1
2020-06-01 Virtual screening, ADME/T, and binding free energy analysis of anti-viral, anti-protease, and anti-infectious compounds against NSP10/NSP16 methyltransferase and main protease of SARS CoV-2 (edit) 10.1080/10799893.2020.1772298
2020-06-01 The pivotal link between ACE2 deficiency and SARS-CoV-2 infection (edit) 10.1016/J.EJIM.2020.04.037
2020-06-01 Comparing the Binding Interactions in the Receptor Binding Domains of SARS-CoV-2 and SARS-CoV (edit) 10.1021/ACS.JPCLETT.0C01064
2020-06-01 Discovery of G-quadruplex-forming sequences in SARS-CoV-2 (edit) 10.1093/BIB/BBAA114
2020-05-30 Structural and Biochemical Characterization of the nsp12-nsp7-nsp8 Core Polymerase Complex from SARS-CoV-2 (edit) 10.1016/J.CELREP.2020.107774
2020-05-30 Evaluation of RdRp & ORF-1b-nsp14-based real-time RT-PCR assays for confirmation of SARS-CoV-2 infection: An observational study (edit) 10.4103/IJMR.IJMR_1256_20
2020-05-29 Optimized pseudotyping conditions for the SARS-COV2 Spike glycoprotein (edit) 10.1101/2020.05.28.122671
2020-05-28 Proteolytic Cleavage of the SARS-CoV-2 Spike Protein and the Role of the Novel S1/S2 Site (edit) 10.1016/J.ISCI.2020.101212
2020-05-26 SARS-CoV-2 strategically mimics proteolytic activation of human ENaC (edit) 10.7554/ELIFE.58603
2020-05-26 A human neutralizing antibody targets the receptor binding site of SARS-CoV-2 (edit) 10.1038/S41586-020-2381-Y
2020-05-24 The ORF8 Protein of SARS-CoV-2 Mediates Immune Evasion through Potently Downregulating MHC-I (edit) 10.1101/2020.05.24.111823
2020-05-22 Chemistry and Biology of SARS-CoV-2 (edit) 10.1016/J.CHEMPR.2020.04.023
2020-05-22 Structural basis for RNA replication by the SARS-CoV-2 polymerase (edit) 10.1016/J.CELL.2020.05.034
2020-05-21 Structure of replicating SARS-CoV-2 polymerase (edit) 10.1038/S41586-020-2368-8
2020-05-21 Trimeric SARS-CoV-2 Spike interacts with dimeric ACE2 with limited intra-Spike avidity (edit) 10.1101/2020.05.21.109157
2020-05-20 SARS-CoV-2 Nsp9 RNA-replicase (edit) 10.2210/PDB6WXD/PDB
2020-05-19 Characterization and noncovalent inhibition of the deubiquitinase and deISGylase activity of SARS-CoV-2 papain-like protease (edit) 10.1021/ACSINFECDIS.0C00168
2020-05-19 Controlling the SARS-CoV-2 Spike Glycoprotein Conformation (edit) 10.1101/2020.05.18.102087
2020-05-19 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2 (edit) 10.1101/2020.05.18.102467
2020-05-18 Architecture and self-assembly of the SARS-CoV-2 nucleocapsid protein (edit) 10.1101/2020.05.17.100685
2020-05-18 Potent neutralizing antibodies against SARS-CoV-2 identified by high-throughput single-cell sequencing of convalescent patients' B cells (edit) 10.1016/J.CELL.2020.05.025
2020-05-18 Ebselen as a highly active inhibitor of PLProCoV2 (edit) 10.1101/2020.05.17.100768
2020-05-18 Distinct conformational states of SARS-CoV-2 spike protein (edit) 10.1101/2020.05.16.099317
2020-05-15 Crystal structures of SARS-CoV-2 ADP-ribose phosphatase (ADRP): from the apo form to ligand complexes (edit) 10.1101/2020.05.14.096081
2020-05-14 Highly Conserved Homotrimer Cavity Formed by the SARS-CoV-2 Spike Glycoprotein: A Novel Binding Site (edit) 10.3390/JCM9051473
2020-05-13 Crystal Structure of Nsp16-Nsp10 Heterodimer from SARS-CoV-2 with 7-methyl-GpppA and S-adenosyl-L-homocysteine in the Active Site and Sulfates in the mRNA Binding Groove (edit) 10.2210/PDB6WRZ/PDB
2020-05-13 Crystal Structure of the Second Form of the Co-factor Complex of NSP7 and the C-terminal Domain of NSP8 from SARS CoV-2 (edit) 10.2210/PDB6WTC/PDB
2020-05-12 SARS-CoV-2 ORF3b is a potent interferon antagonist whose activity is further increased by a naturally occurring elongation variant (edit) 10.1101/2020.05.11.088179
2020-05-11 SARS-CoV-2 spike protein binds heparan sulfate in a length- and sequence-dependent manner (edit) 10.1101/2020.05.10.087288
2020-05-10 Human Intestinal Defensin 5 Inhibits SARS-CoV-2 Invasion by Cloaking ACE2 (edit) 10.1053/J.GASTRO.2020.05.015
2020-05-06 Structure of SARS-CoV-2 nsp16/nsp10 ternary complex (edit) 10.2210/PDB6WKS/PDB
2020-05-06 The anti-HIV Drug Nelfinavir Mesylate (Viracept) is a Potent Inhibitor of Cell Fusion Caused by the SARS-CoV-2 Spike (S) Glycoprotein Warranting further Evaluation as an Antiviral against COVID-19 infections (edit) 10.1002/JMV.25985
2020-05-06 Cell entry mechanisms of SARS-CoV-2 (edit) 10.1073/PNAS.2003138117
2020-05-06 The 1.95 A Crystal Structure of the Co-factor Complex of NSP7 and the C-terminal Domain of NSP8 from SARS-CoV-2 (edit) 10.2210/PDB6WQD/PDB
2020-05-05 Proteolytic Cleavage of the SARS-CoV-2 Spike Protein and the Role of the Novel S1/S2 Site (edit) 10.2139/SSRN.3581359
2020-05-05 SARS-CoV-2 and ORF3a: Nonsynonymous Mutations, Functional Domains, and Viral Pathogenesis (edit) 10.1128/MSYSTEMS.00266-20
2020-05-05 Nsp7 and Spike Glycoprotein of SARS-CoV-2 Are Envisaged as Potential Targets of Vitamin D and Ivermectin (edit) 10.20944/PREPRINTS202005.0084.V1
2020-05-04 Deducing the N- and O- glycosylation profile of the spike protein of novel coronavirus SARS-CoV-2 (edit) 10.1093/GLYCOB/CWAA042
2020-05-04 Site-specific glycan analysis of the SARS-CoV-2 spike (edit) 10.1126/SCIENCE.ABB9983
2020-05-01 Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir (edit) 10.1126/SCIENCE.ABC1560
2020-04-30 A SARS-CoV-2 protein interaction map reveals targets for drug repurposing (edit) 10.1038/S41586-020-2286-9
2020-04-30 Biochemical characterization of SARS-CoV-2 nucleocapsid protein (edit) 10.1016/J.BBRC.2020.04.136
2020-04-30 SARS-CoV-2 Spike S1 Receptor Binding Domain undergoes Conformational Change upon Interaction with Low Molecular Weight Heparins (edit) 10.1101/2020.04.29.068486
2020-04-30 Glycosaminoglycans induce conformational change in the SARS-CoV-2 Spike S1 Receptor Binding Domain (edit) 10.1101/2020.04.29.068767
2020-04-29 An in-silico evaluation of different Saikosaponins for their potency against SARS-CoV-2 using NSP15 and fusion spike glycoprotein as targets (edit) 10.1080/07391102.2020.1762741
2020-04-29 High-resolution structure of the SARS-CoV-2 NSP3 Macro X domain (edit) 10.2210/PDB6WEY/PDB
2020-04-29 STRUCTURE OF THE SARS-CoV-2 ORF7A ENCODED ACCESSORY PROTEIN (edit) 10.2210/PDB6W37/PDB
2020-04-28 A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells (edit) 10.1016/J.MOLCEL.2020.04.022
2020-04-28 Structural elucidation of SARS-CoV-2 vital proteins: Computational methods reveal potential drug candidates against main protease, Nsp12 polymerase and Nsp13 helicase (edit) 10.1016/J.JPHA.2020.04.008
2020-04-27 Structural Basis of RNA Cap Modification by SARS-CoV-2 Coronavirus (edit) 10.1101/2020.04.26.061705
2020-04-25 Validation of a SARS-CoV-2 spike protein ELISA for use in contact investigations and sero-surveillance (edit) 10.1101/2020.04.24.057323
2020-04-22 Crystal structure of the co-factor complex of NSP7 and the C-terminal domain of NSP8 from SARS CoV-2 (edit) 10.2210/PDB6WIQ/PDB
2020-04-20 The crystal structure of nsp10-nsp16 heterodimer from SARS-CoV-2 in complex with S-adenosylmethionine (edit) 10.1101/2020.04.17.047498
2020-04-17 Crystal structure of Nsp15 endoribonuclease NendoU from SARS-CoV-2 (edit) 10.1002/PRO.3873
2020-04-15 Discovery of baicalin and baicalein as novel, natural product inhibitors of SARS-CoV-2 3CL protease in vitro (edit) 10.1101/2020.04.13.038687
2020-04-11 On the interactions of the receptor-binding domain of SARS-CoV-1 and SARS-CoV-2 spike proteins with monoclonal antibodies and the receptor ACE2 (edit) 10.1101/2020.04.05.026377
2020-04-10 SARS-CoV-2-encoded nucleocapsid protein acts as a viral suppressor of RNA interference in cells (edit) 10.1007/S11427-020-1692-1
2020-04-10 Evolutionary analysis of SARS-CoV-2: how mutation of Non-Structural Protein 6 (NSP6) could affect viral autophagy (edit) 10.1016/J.JINF.2020.03.058
2020-04-10 Structure of the RNA-dependent RNA polymerase from COVID-19 virus (edit) 10.1126/SCIENCE.ABB7498
2020-04-10 Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites (edit) 10.1016/J.ANTIVIRAL.2020.104793
2020-04-09 Structure of Mpro from COVID-19 virus and discovery of its inhibitors (edit) 10.1038/S41586-020-2223-Y
2020-04-08 Development of a Novel, Genome Subtraction-Derived, SARS-CoV-2-Specific COVID-19-nsp2 Real-Time RT-PCR Assay and Its Evaluation Using Clinical Specimens (edit) 10.3390/IJMS21072574
2020-04-06 Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein (edit) 10.1101/2020.04.02.022194
2020-04-02 Molecular Basis for ADP-ribose Binding to the Macro-X Domain of SARS-CoV-2 Nsp3 (edit) 10.1101/2020.03.31.014639
2020-04-01 The crystal structure of papain-like protease of SARS CoV-2 (edit) 10.2210/PDB6W9C/PDB
2020-03-31 Crystal structure of the SARS-CoV-2 non-structural protein 9, Nsp9 (edit) 10.1101/2020.03.28.013920
2020-03-30 Structural basis of receptor recognition by SARS-CoV-2 (edit) 10.1038/S41586-020-2179-Y
2020-03-30 Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor (edit) 10.1038/S41586-020-2180-5
2020-03-30 Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion (edit) 10.1038/S41422-020-0305-X
2020-03-30 Site-specific N-glycosylation Characterization of Recombinant SARS-CoV-2 Spike Proteins (edit) 10.1101/2020.03.28.013276
2020-03-29 The Nucleocapsid Protein of SARS-CoV-2 Abolished Pluripotency in Human Induced Pluripotent Stem Cells (edit) 10.1101/2020.03.26.010694
2020-03-28 Molecular characterization of SARS-CoV-2 in the first COVID-19 cluster in France reveals an amino acid deletion in nsp2 (Asp268del) (edit) 10.1016/J.CMI.2020.03.020
2020-03-27 Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV (edit) 10.1038/S41467-020-15562-9
2020-03-25 Crystal Structure of the methyltransferase-stimulatory factor complex of NSP16 and NSP10 from SARS CoV-2 (edit) 10.2210/PDB6W61/PDB
2020-03-22 Molecular characterization of SARS-CoV-2 in the first COVID-19 cluster in France reveals an amino-acid deletion in nsp2 (Asp268Del) (edit) 10.1101/2020.03.19.998179
2020-03-20 Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors (edit) 10.1126/SCIENCE.ABB3405
2020-03-20 The first-in-class peptide binder to the SARS-CoV-2 spike protein (edit) 10.1101/2020.03.19.999318
2020-03-18 1.80 Angstrom Resolution Crystal Structure of NSP16 - NSP10 Complex from SARS-CoV-2 (edit) 10.2210/PDB6W4H/PDB
2020-03-18 Crystal structure of SARS-CoV-2 nucleocapsid protein N-terminal RNA binding domain (edit) 10.2210/PDB6M3M/PDB
2020-03-18 Crystal structure of SARS-CoV-2 spike receptor-binding domain bound with ACE2 (edit) 10.2210/PDB6M0J/PDB
2020-03-18 The crystal structure of Nsp9 RNA binding protein of SARS CoV-2 (edit) 10.2210/PDB6W4B/PDB
2020-03-18 Structure of RNA-dependent RNA polymerase from 2019-nCoV, a major antiviral drug target (edit) 10.1101/2020.03.16.993386
2020-03-15 SARS-CoV-2 invades host cells via a novel route: CD147-spike protein (edit) 10.1101/2020.03.14.988345
2020-03-13 The inhaled corticosteroid ciclesonide blocks coronavirus RNA replication by targeting viral NSP15 (edit) 10.1101/2020.03.11.987016
2020-03-11 The crystal structure of COVID-19 main protease in apo form (edit) 10.2210/PDB6M03/PDB
2020-03-11 COVID-19 main protease with unliganded active site (2019-nCoV, coronavirus disease 2019, SARS-CoV-2) (edit) 10.2210/PDB6Y84/PDB
2020-03-11 PanDDA analysis group deposition -- Crystal Structure of COVID-19 main protease in complex with Z1367324110 (edit) 10.2210/PDB5R81/PDB
2020-03-11 PanDDA analysis group deposition -- Crystal Structure of COVID-19 main protease in complex with Z219104216 (edit) 10.2210/PDB5R82/PDB
2020-03-11 PanDDA analysis group deposition -- Crystal Structure of COVID-19 main protease in complex with Z44592329 (edit) 10.2210/PDB5R83/PDB
2020-03-11 Crystal Structure of ADP ribose phosphatase of NSP3 from SARS CoV-2 in the complex with ADP ribose (edit) 10.2210/PDB6W02/PDB
2020-03-10 Whole Genome Sequence Analysis and Homology Modelling of a 3C Like Peptidase and a Non-Structural Protein 3 of the SARS-CoV-2 Shows Protein Ligand Interaction with an Aza-Peptide and a Noncovalent Lead Inhibitor with Possible Antiviral Properties (edit) 10.26434/CHEMRXIV.11846943
2020-03-09 Substrate specificity profiling of SARS-CoV-2 Mpro protease provides basis for anti-COVID-19 drug design (edit) 10.1101/2020.03.07.981928
2020-03-06 Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein (edit) 10.1016/J.CELL.2020.02.058
2020-03-04 Crystal structure of the free enzyme of the SARS-CoV-2 (2019-nCoV) main protease (edit) 10.2210/PDB6Y2E/PDB
2020-03-04 Crystal structure (monoclinic form) of the complex resulting from the reaction between SARS-CoV-2 (2019-nCoV) main protease and tert-butyl (1-((S)-1-(((S)-4-(benzylamino)-3,4-dioxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2-yl)amino)-3-cyclopropyl-1-oxoprop (edit) 10.2210/PDB6Y2F/PDB
2020-03-04 Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2 (edit) 10.1126/SCIENCE.ABB2762
2020-03-04 SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor (edit) 10.1016/J.CELL.2020.02.052
2020-03-04 Crystal Structure of ADP ribose phosphatase of NSP3 from SARS CoV-2 (edit) 10.2210/PDB6VXS/PDB
2020-03-03 Crystal structure of Nsp15 endoribonuclease NendoU from SARS-CoV-2 (edit) 10.1101/2020.03.02.968388
2020-03-02 Potential Inhibitors Targeting RNA-Dependent RNA Polymerase Activity (NSP12) of SARS-CoV-2 (edit) 10.20944/PREPRINTS202003.0024.V1
2020-02-28 Anti-HCV, nucleotide inhibitors, repurposing against COVID-19 (edit) 10.1016/J.LFS.2020.117477
2020-02-27 Structure of Mpro from COVID-19 virus and discovery of its inhibitors (edit) 10.1101/2020.02.26.964882
2020-02-21 COVID-2019: The role of the nsp2 and nsp3 in its pathogenesis (edit) 10.1002/JMV.25719
2020-02-20 Structure, function and antigenicity of the SARS-CoV-2 spike glycoprotein (edit) 10.1101/2020.02.19.956581
2020-02-19 Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation (edit) 10.1126/SCIENCE.ABB2507
2020-02-17 Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody (edit) 10.1080/22221751.2020.1729069
2020-02-16 Cryo-EM Structure of the 2019-nCoV Spike in the Prefusion Conformation (edit) 10.1101/2020.02.11.944462
2020-02-12 The insert sequence in SARS-CoV-2 enhances spike protein cleavage by TMPRSS (edit) 10.1101/2020.02.08.926006
2020-02-11 Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein (edit) 10.1038/S41423-020-0374-2
2020-02-05 The crystal structure of COVID-19 main protease in complex with an inhibitor N3 (edit) 10.2210/PDB6LU7/PDB
2020-01-31 Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag (edit) 10.1101/2020.01.30.927871
2020-01-22 Homologous recombination within the spike glycoprotein of the newly identified coronavirus may boost cross‐species transmission from snake to human (edit) 10.1002/JMV.25682
2020-01-01 The Nucleocapsid Protein of SARS-CoV-2 Abolished Pluripotency in Human Induced Pluripotent Stem Cells (edit) 10.2139/SSRN.3561932
2020-01-01 Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties (edit) 10.1039/D0NJ00974A
2020-01-01 3-Hydroxyphthalic Anhydride-Modified Chicken Ovalbumin as a Potential Candidate Inhibits SARS-CoV-2 Infection by Disrupting the Interaction of Spike Protein With Host ACE2 Receptor (edit) 10.3389/FPHAR.2020.603830
2020-01-01 Structural Insight  Reveals SARS-CoV-2 Orf7a as an Immunomodulating Factor for Human CD14+ Monocytes (edit) 10.2139/SSRN.3699795
2006-06-14 Accelerated induction of apoptosis in insect cells by baculovirus-expressed SARS-CoV membrane protein (edit) 10.1016/J.FEBSLET.2006.06.003
Crystal Structure of NSP15 Endoribonuclease from SARS CoV-2 (edit) 10.2210/PDB6VWW/PDB
SARS-CoV-2 infects cells after viral entry via clathrin-mediated endocytosis (edit) 10.1016/J.JBC.2021.100306
The chaperone GRP78 is a host auxiliary factor for SARS-CoV-2 and GRP78 depleting antibody blocks viral entry and infection (edit) 10.1016/J.JBC.2021.100759

Code examples

curl

curl -s https://raw.githubusercontent.com/egonw/SARS-CoV-2-Queries/master/sparql/litSARSCoV2Proteins.rq | sed 's+<lang/>+en+' > litSARSCoV2Proteins.rq

curl -H "Accept: text/tab-separated-values" -G https://query.wikidata.org/bigdata/namespace/wdq/sparql --data-urlencode query@litSARSCoV2Proteins.rq

This SPARQL query is available under CCZero.