SARS-CoV-2-Queries

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Literatura

Estas buscas retornoma os últimos 10 artigos sobre uma série de temas.Não é um substituto para o Scholia [1], que tem uma visão muito mais rica da literatura sobre el tema. Cada seção inclui uma ligação à página do Scholia para esse tema. As consultas feitas aqui são básicas e usam somente a propriedade “tópico principal da obra”.

Literatura sobre SARS-CoV-2

SARS-CoV-2 es el nombre del virus.

SPARQL sparql/litSARSCoV2.rq (run, edit)

SELECT (MAX(?dates) as ?date) ?work ?workLabel ?doi WHERE {
  ?work wdt:P921 wd:Q82069695 .
  OPTIONAL { ?work wdt:P577 ?dates . }
  OPTIONAL { ?work wdt:P356 ?doi . }
  SERVICE wikibase:label { bd:serviceParam wikibase:language "pt,en". }
} GROUP BY ?work ?workLabel ?doi ORDER BY DESC(?date) ?work

Isto te fornece 10 documentos:

date work doi
2021-03-01 Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo (edit) 10.1084/JEM.20201993
2021-03-01 Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients (edit) 10.1084/JEM.20201707
2021-03-01 Urological tumors treatment in Brazil during the SARS-Cov-2 outbrake (edit) 10.1590/S1677-5538.IBJU.2020.0479.1
2021-02-24 The British variant of the new coronavirus-19 (Sars-Cov-2) should not create a vaccine problem (edit)
2021-02-01 Targeting host cell proteases as a potential treatment strategy to limit the spread of SARS-CoV-2 in the respiratory tract (edit) 10.1002/PRP2.698
2021-01-08 Beschluss der STIKO zur 1. Aktualisierung der COVID-19-Impfempfehlung und die dazugehörige wissenschaftliche Begründung (edit) 10.25646/7820
2021-01-07 Exploration of natural compounds with anti-SARS-CoV-2 activity via inhibition of SARS-CoV-2 Mpro (edit) 10.1093/BIB/BBAA382
2021-01-07 Critical role of neutralizing antibody for SARS-CoV-2 reinfection and transmission (edit) 10.1080/22221751.2021.1872352
null sparql/litSARSCoV2.rq

Literatura sobre genes do SARS-CoV-2

Também podemos consultar artigos sobre os genes relacionados à COVID-19:

SPARQL sparql/litSARSCoV2Genes.rq (run, edit)

SELECT (MAX(?dates) as ?date) ?work ?workLabel ?doi WHERE {
  ?gene wdt:P703 wd:Q82069695 ; wdt:P31 wd:Q7187 .
  ?work wdt:P921 ?gene .
  OPTIONAL { ?work wdt:P577 ?dates . }
  OPTIONAL { ?work wdt:P356 ?doi . }
  SERVICE wikibase:label { bd:serviceParam wikibase:language "pt,en". }
} GROUP BY ?work ?workLabel ?doi ORDER BY DESC(?date)

Que atualmente dá:

date work doi
2020-08-18 Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study (edit) 10.1016/S0140-6736(20)31757-8
2020-07-21 Discovery and Genomic Characterization of a 382-Nucleotide Deletion in ORF7b and ORF8 during the Early Evolution of SARS-CoV-2 (edit) 10.1128/MBIO.01610-20
2020-06-22 A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2 (edit) 10.1126/SCIENCE.ABC6952
2020-06-16 SARS-CoV-2 genomic surveillance in Taiwan revealed novel ORF8-deletion mutant and clade possibly associated with infections in Middle East (edit) 10.1080/22221751.2020.1782271
2020-05-25 Genomic surveillance of SARS-CoV-2 in Thailand reveals mixed imported populations, a local lineage expansion and a virus with truncated ORF7a (edit) 10.1101/2020.05.22.20108498
2020-05-18 Molecular conservation and Differential mutation on ORF3a gene in Indian SARS-CoV2 genomes (edit) 10.1101/2020.05.14.096107
2020-04-30 A SARS-CoV-2 protein interaction map reveals targets for drug repurposing (edit) 10.1038/S41586-020-2286-9
2020-04-20 Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites (edit) 10.1016/J.APSB.2020.04.009
null sparql/litSARSCoV2Genes.rq

Literatura sobre proteínas do SARS-CoV-2

E sobre as proteínas do virus:

SPARQL sparql/litSARSCoV2Proteins.rq (run, edit)

SELECT (MAX(?dates) as ?date) ?work ?workLabel ?doi WHERE {
  ?protein wdt:P703 wd:Q82069695 ; wdt:P31 wd:Q8054 .
  ?work wdt:P921 ?protein .
  OPTIONAL { ?work wdt:P577 ?dates . }
  OPTIONAL { ?work wdt:P356 ?doi . }
  SERVICE wikibase:label { bd:serviceParam wikibase:language "pt,en". }
} GROUP BY ?work ?workLabel ?doi ORDER BY DESC(?date)

Que atualmente dá:

date work doi
2021-01-01 Overexpression of SARS-CoV-2 protein ORF6 dislocates RAE1 and NUP98 from the nuclear pore complex (edit) 10.1016/J.BBRC.2020.11.115
2020-12-31 A novel virtual screening procedure identifies Pralatrexate as inhibitor of SARS-CoV-2 RdRp and it reduces viral replication in vitro (edit) 10.1371/JOURNAL.PCBI.1008489
2020-12-16 Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase (edit) 10.1016/J.BPJ.2020.11.2276
2020-12-11 High-Throughput Screening and Quantum Mechanics for Identifying Potent Inhibitors against Mac1 Domain of SARS-CoV-2 Nsp3 (edit) 10.1109/TCBB.2020.3037136
2020-12-10 SARS-CoV-2 Nsp16 activation mechanism and a cryptic pocket with pan-coronavirus antiviral potential (edit) 10.1101/2020.12.10.420109
2020-12-09 Ritonavir may inhibit exoribonuclease activity of nsp14 from the SARS-CoV-2 virus and potentiate the activity of chain terminating drugs (edit) 10.1016/J.IJBIOMAC.2020.12.038
2020-12-07 Spike Protein of SARS-CoV-2 Activates Macrophages and Contributes to Induction of Acute Lung Inflammations in Mice (edit) 10.1101/2020.12.07.414706
2020-12-03 1H, 13C, and 15N backbone chemical shift assignments of the C-terminal dimerization domain of SARS-CoV-2 nucleocapsid protein (edit) 10.1007/S12104-020-09995-Y
null sparql/litSARSCoV2Proteins.rq

Literatura sobre os coronavírus

Como descrevemos no capítulo ??,, o SARS-Cov-2 é somente um dos coronavirus que podem infectar seres humanos.

SPARQL sparql/litCoronaviruses.rq (run, edit)

SELECT (MAX(?dates) as ?date) ?work ?workLabel ?doi WHERE {
  ?work wdt:P921 wd:Q57751738 .
  OPTIONAL { ?work wdt:P577 ?dates . }
  OPTIONAL { ?work wdt:P356 ?doi . }
  SERVICE wikibase:label { bd:serviceParam wikibase:language "pt,en". }
} GROUP BY ?work ?workLabel ?doi ORDER BY DESC(?date)

A busca te dá estes 10 documentos:

date work doi
2020-04-01 [Recommendations for critically ill patients with COVID-19] (edit) 10.1007/S00063-020-00674-3
2020-03-27 A new threat from an old enemy: Re‑emergence of coronavirus (Review) (edit) 10.3892/IJMM.2020.4555
2020-02-26 Potential Rapid Diagnostics, Vaccine and Therapeutics for 2019 Novel Coronavirus (2019-nCoV): A Systematic Review (edit) 10.3390/JCM9030623
2020-02-14 The First Disease X is Caused by a Highly Transmissible Acute Respiratory Syndrome Coronavirus (edit) 10.1007/S12250-020-00206-5

Literatura sobre os coronavírus humanos

Há mais de 6000 artigos sobre os sete coronavírus humanos em Wikidata. Por isso, a consulta está ajustada para desempenho e, por isso, tem uma estrutura mais complexa. Além disso, a lista é enorme e não cabe na página. Para ver o resultado, clique na continuação no nome do arquivo litHumanCoronaviruses.rq:

SPARQL sparql/litHumanCoronaviruses.rq (run, edit)

SELECT ?date ?work ?workLabel ?virus ?virusLabel ?doi ?pubmed WITH {
  SELECT (MAX(?dates) as ?date) ?work ?doi ?virus WHERE {
    VALUES ?virus {
      wd:Q82069695 # SARS-CoV-2
      wd:Q16983360 # HKU1
      wd:Q16991954 # OC43
      wd:Q8351095  # NL63 
      wd:Q16983356 # 229E 
      wd:Q4902157  # MERS-CoV
      wd:Q278567   # SARS-CoV
    }
    ?work wdt:P577 ?dates ;
          wdt:P921 ?virus .
  } GROUP BY ?work ?doi ?virus
    ORDER BY DESC(?date)
    LIMIT 5000
} AS %ARTICLES WHERE {
  INCLUDE %ARTICLES
  OPTIONAL { ?work wdt:P356 ?doi . }
  OPTIONAL { ?work wdt:P698 ?pubmed . }
  SERVICE wikibase:label { bd:serviceParam wikibase:language "pt,en". }
}
ORDER BY DESC(?date) ?doi ?pubmed ?virus

Além disso, o número de artigos para cada vírus varia notavelmnte, o que pode ser visualizado com essa consulta:

SPARQL sparql/litHumanCoronavirusesCounts.rq (run, edit)

SELECT ?virus ?virusLabel ?count WITH {
  SELECT ?virus (COUNT(DISTINCT ?work) AS ?count) WHERE {
    VALUES ?virus {
      wd:Q82069695 # SARS-CoV-2
      wd:Q16983360 # HKU1
      wd:Q16991954 # OC43
      wd:Q8351095  # NL63 
      wd:Q16983356 # 229E 
      wd:Q4902157  # MERS-CoV
      wd:Q278567   # SARS-CoV
    }
    ?work wdt:P921 ?virus .
  } GROUP BY ?virus
} AS %ARTICLES WHERE {
  INCLUDE %ARTICLES
  SERVICE wikibase:label { bd:serviceParam wikibase:language "pt,en". }
}
ORDER BY DESC(?count)

O que nos diz:

virus count
coronavírus da síndrome respiratória aguda grave 2 (edit) 18286
SARS-CoV (edit) 2480
Síndrome respiratória por coronavírus do Oriente Médio (edit) 1041
Coronavírus humano OC43 (edit) 91
Coronavírus humano 229E (edit) 84
Coronavírus humano NL63 (edit) 79
Coronavírus humano HKU1 (edit) 21

e seus genes

SPARQL sparql/litHumanCoronavirusesGeneCounts.rq (run, edit)

SELECT ?virus ?virusLabel ?gene ?geneLabel ?count WITH {
  SELECT ?virus ?gene (COUNT(DISTINCT ?work) AS ?count) WHERE {
    VALUES ?virus {
      wd:Q82069695 # SARS-CoV-2
      wd:Q16983360 # HKU1
      wd:Q16991954 # OC43
      wd:Q8351095  # NL63 
      wd:Q16983356 # 229E 
      wd:Q4902157  # MERS-CoV
      wd:Q278567   # SARS-CoV
    }
    ?gene wdt:P703 ?virus ; wdt:P31 wd:Q7187 .
    ?work wdt:P921 ?gene .
  } GROUP BY ?virus ?gene
} AS %ARTICLES WHERE {
  INCLUDE %ARTICLES
  SERVICE wikibase:label { bd:serviceParam wikibase:language "pt,en". }
}
ORDER BY DESC(?count)

O que nos mostra:

virus gene count
coronavírus da síndrome respiratória aguda grave 2 (edit) ORF8 protein (edit) 6
Coronavírus humano NL63 (edit) membrane protein (edit) 3
Coronavírus humano NL63 (edit) nucleocapsid protein (edit) 3
Coronavírus humano NL63 (edit) envelope protein (edit) 3
Coronavírus humano NL63 (edit) spike protein (edit) 3
Coronavírus humano NL63 (edit) replicase polyprotein 1ab (edit) 2
Coronavírus humano NL63 (edit) protein 3 (edit) 2
Coronavírus humano 229E (edit) nucleocapsid protein (edit) 2
Coronavírus humano 229E (edit) surface glycoprotein (edit) 2
Coronavírus humano OC43 (edit) spike surface glycoprotein (edit) 2
coronavírus da síndrome respiratória aguda grave 2 (edit) nucleocapsid phosphoprotein (edit) 2
coronavírus da síndrome respiratória aguda grave 2 (edit) ORF7b (edit) 2
coronavírus da síndrome respiratória aguda grave 2 (edit) ORF3a protein (edit) 2
coronavírus da síndrome respiratória aguda grave 2 (edit) surface glycoprotein (edit) 2
Coronavírus humano 229E (edit) envelope protein (edit) 1
Coronavírus humano 229E (edit) membrane protein (edit) 1
Coronavírus humano 229E (edit) 4b protein (edit) 1
Coronavírus humano 229E (edit) 4a protein (edit) 1
Coronavírus humano OC43 (edit) membrane protein (edit) 1
Coronavírus humano OC43 (edit) nucleocapsid protein (edit) 1
Coronavírus humano OC43 (edit) ns2 (edit) 1
Coronavírus humano HKU1 (edit) membrane glycoprotein (edit) 1
Coronavírus humano HKU1 (edit) hemagglutinin-esterase glycoprotein (edit) 1
Coronavírus humano HKU1 (edit) orf1ab polyprotein (edit) 1
Coronavírus humano HKU1 (edit) nucleocapsid phosphoprotein (edit) 1
Coronavírus humano HKU1 (edit) small membrane protein (edit) 1
Coronavírus humano HKU1 (edit) spike glycoprotein (edit) 1
coronavírus da síndrome respiratória aguda grave 2 (edit) ORF7a protein (edit) 1
coronavírus da síndrome respiratória aguda grave 2 (edit) membrane glycoprotein (edit) 1
coronavírus da síndrome respiratória aguda grave 2 (edit) envelope protein (edit) 1
coronavírus da síndrome respiratória aguda grave 2 (edit) ORF1a polyprotein;ORF1ab polyprotein (edit) 1

e sua proteínas

SPARQL sparql/litHumanCoronavirusesProteinCounts.rq (run, edit)

SELECT ?virus ?virusLabel ?protein ?proteinLabel ?count WITH {
  SELECT ?virus ?protein (COUNT(DISTINCT ?work) AS ?count) WHERE {
    VALUES ?virus {
      wd:Q82069695 # SARS-CoV-2
      wd:Q16983360 # HKU1
      wd:Q16991954 # OC43
      wd:Q8351095  # NL63 
      wd:Q16983356 # 229E 
      wd:Q4902157  # MERS-CoV
      wd:Q278567   # SARS-CoV
    }
    ?protein wdt:P31 wd:Q8054 .
    { ?protein wdt:P703 ?virus }
    UNION
    { ?protein wdt:P702 | ^wdt:P688 ?gene . ?gene wdt:P703 ?virus }
    ?work wdt:P921 ?protein .
  } GROUP BY ?virus ?protein
} AS %ARTICLES WHERE {
  INCLUDE %ARTICLES
  SERVICE wikibase:label { bd:serviceParam wikibase:language "pt,en". }
}
ORDER BY DESC(?count) ?virus ?protein

Onde encontramos:

virus protein count
coronavírus da síndrome respiratória aguda grave 2 (edit) spike glycoprotein [SARS-CoV-2] (edit) 94
SARS-CoV (edit) spike glycoprotein [SARS-Cov] (edit) 83
SARS-CoV (edit) nucleoprotein [SARS-Cov] (edit) 60
SARS-CoV (edit) 3C-like proteinase [SARS-Cov] (edit) 56
SARS-CoV (edit) Protein 3a [SARS-Cov] (edit) 39
SARS-CoV (edit) papain-like proteinase [SARS-Cov] (edit) 37
coronavírus da síndrome respiratória aguda grave 2 (edit) nucleocapsid protein [SARS-CoV-2] (edit) 37
SARS-CoV (edit) Envelope small membrane protein [SARS-Cov] (edit) 36
coronavírus da síndrome respiratória aguda grave 2 (edit) Non-structural protein 10 [SARS CoV-2] (edit) 25
coronavírus da síndrome respiratória aguda grave 2 (edit) Host translation inhibitor nsp1 [SARS-CoV-2] (edit) 25
coronavírus da síndrome respiratória aguda grave 2 (edit) non-structural protein 16 [SARS-CoV-2] (edit) 24
SARS-CoV (edit) Membrane protein [SARS-Cov] (edit) 23
coronavírus da síndrome respiratória aguda grave 2 (edit) RNA-directed RNA polymerase [SARS-CoV-2] (edit) 23
coronavírus da síndrome respiratória aguda grave 2 (edit) Papain-like proteinase [SARS-CoV-2] (edit) 22
coronavírus da síndrome respiratória aguda grave 2 (edit) non-structural protein 5 [SARS-CoV-2] (edit) 19
SARS-CoV (edit) Non-structural protein NS6 [SARS-Cov] (edit) 14
SARS-CoV (edit) Protein 7a [SARS-Cov] (edit) 14
coronavírus da síndrome respiratória aguda grave 2 (edit) Helicase [SARS-CoV-2] (edit) 14
SARS-CoV (edit) host translation inhibitor nsp1 [SARS-Cov] (edit) 12
coronavírus da síndrome respiratória aguda grave 2 (edit) non-structural protein 15 [SARS-CoV-2] (edit) 12
coronavírus da síndrome respiratória aguda grave 2 (edit) Non-structural protein 14 [SARS-CoV-2] (edit) 12
coronavírus da síndrome respiratória aguda grave 2 (edit) Non-structural protein nsp8 [SARS-CoV-2] (edit) 12
coronavírus da síndrome respiratória aguda grave 2 (edit) Non-structural protein 7 [SARS-CoV-2] (edit) 11
SARS-CoV (edit) Guanine-N7 methyltransferase [SARS-Cov] (edit) 10
Síndrome respiratória por coronavírus do Oriente Médio (edit) spike glycoprotein (edit) 10
SARS-CoV (edit) Non-structural protein 3b [SARS-Cov] (edit) 9
SARS-CoV (edit) 2'-O-methyltransferase [SARS-Cov] (edit) 9
coronavírus da síndrome respiratória aguda grave 2 (edit) envelope protein [SARS-CoV-2] (edit) 9
SARS-CoV (edit) Protein 9b [SARS-Cov] (edit) 8
SARS-CoV (edit) uridylate-specific endoribonuclease [SARS-Cov] (edit) 8
SARS-CoV (edit) protein non-structural 8a [SARS-Cov] (edit) 8
SARS-CoV (edit) protein non-structural 8b [SARS-Cov] (edit) 8
coronavírus da síndrome respiratória aguda grave 2 (edit) Non-structural protein 9 [SARS-CoV-2] (edit) 8
SARS-CoV (edit) non-structural protein 10 [SARS-Cov] (edit) 7
SARS-CoV (edit) RNA-directed RNA polymerase [SARS-Cov] (edit) 7
coronavírus da síndrome respiratória aguda grave 2 (edit) Viroporin 3a [SARS-CoV-2] (edit) 7
coronavírus da síndrome respiratória aguda grave 2 (edit) membrane protein [SARS-CoV-2] (edit) 7
coronavírus da síndrome respiratória aguda grave 2 (edit) ORF8 protein [SARS-CoV-2] (edit) 7
SARS-CoV (edit) replicase polyprotein 1ab [SARS-Cov] (edit) 6
SARS-CoV (edit) non-structural protein 7 [SARS-Cov] (edit) 6
SARS-CoV (edit) non-structural protein 8 [SARS-Cov] (edit) 6
SARS-CoV (edit) helicase [SARS-Cov] (edit) 6
coronavírus da síndrome respiratória aguda grave 2 (edit) Non-structural protein 2 [SARS CoV-2] (edit) 6
coronavírus da síndrome respiratória aguda grave 2 (edit) ORF6 protein [SARS-CoV-2] (edit) 6
Coronavírus humano OC43 (edit) nucleocapsid protein (edit) 5
SARS-CoV (edit) Protein non-structural 7b [SARS-Cov] (edit) 5
SARS-CoV (edit) non-structural protein 9 [SARS-Cov] (edit) 5
coronavírus da síndrome respiratória aguda grave 2 (edit) ORF3b protein [SARS-CoV-2] (edit) 5
Coronavírus humano NL63 (edit) Spike glycoprotein [NL63] (edit) 5
Coronavírus humano OC43 (edit) spike surface glycoprotein (edit) 4
SARS-CoV (edit) non-structural protein 4 [SARS-Cov] (edit) 4
coronavírus da síndrome respiratória aguda grave 2 (edit) non-structural protein 6 [SARS-CoV-2] (edit) 4
Coronavírus humano HKU1 (edit) Spike glycoprotein (edit) 3
SARS-CoV (edit) non-structural protein 6 [SARS-Cov] (edit) 3
Síndrome respiratória por coronavírus do Oriente Médio (edit) nucleoprotein (edit) 3
coronavírus da síndrome respiratória aguda grave 2 (edit) Protein 7a [SARS-CoV-2] (edit) 3
coronavírus da síndrome respiratória aguda grave 2 (edit) ORF10 protein [SARS-CoV-2] (edit) 3
coronavírus da síndrome respiratória aguda grave 2 (edit) Protein ORF9b [SARS-CoV-2] (edit) 3
coronavírus da síndrome respiratória aguda grave 2 (edit) Non-structural protein 4 [SARS-CoV-2] (edit) 3
Coronavírus humano 229E (edit) Non-structural protein 4b (edit) 2
Coronavírus humano 229E (edit) Spike glycoprotein (edit) 2
Coronavírus humano HKU1 (edit) Replicase polyprotein 1ab (edit) 2
Coronavírus humano OC43 (edit) ns12.9 (edit) 2
Coronavírus humano OC43 (edit) hemagglutinin-esterase (edit) 2
SARS-CoV (edit) non-structural protein 2 [SARS-Cov] (edit) 2
coronavírus da síndrome respiratória aguda grave 2 (edit) orf1ab polyprotein [SARS-Cov 2] (edit) 2
Coronavírus humano NL63 (edit) Nucleoprotein (edit) 2
Coronavírus humano 229E (edit) Non-structural protein 4a (edit) 1
Coronavírus humano 229E (edit) Nucleoprotein (edit) 1
Coronavírus humano 229E (edit) Replicase polyprotein 1ab (edit) 1
Coronavírus humano HKU1 (edit) Spike glycoprotein (edit) 1
Coronavírus humano HKU1 (edit) Membrane protein (edit) 1
Coronavírus humano OC43 (edit) ns2 (edit) 1
Coronavírus humano OC43 (edit) membrane protein (edit) 1
SARS-CoV (edit) spike protein S2 [SARS-Cov] (edit) 1
SARS-CoV (edit) Replicase polyprotein 1a (edit) 1
Síndrome respiratória por coronavírus do Oriente Médio (edit) NS4B protein (edit) 1
coronavírus da síndrome respiratória aguda grave 2 (edit) putative protein ORF3c (edit) 1
coronavírus da síndrome respiratória aguda grave 2 (edit) Non-structural protein 11 [SARS CoV-2] (edit) 1
coronavírus da síndrome respiratória aguda grave 2 (edit) ORF9c protein [SARS CoV-2] (edit) 1
Coronavírus humano NL63 (edit) Membrane protein (edit) 1

Referências

  1. Rasberry L, Willighagen E, Nielsen FÅ, Mietchen D. Robustifying Scholia: paving the way for knowledge discovery and research assessment through Wikidata. RIO Journal [Internet]. 2019 May 2;5. Available from: https://riojournal.com/article/35820/ doi:10.3897/RIO.5.E35820 (Scholia)